Shanghai Sunite Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov chaw muag khoom ntawm -amyloid (1-34) cas 186359-65-9 hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau kev lag luam wholesale zoo-amyloid (1-34) cas 186359-65-9 los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 186359 -}}65-9; Amyloid (1-34) |
| Ib ntus | DAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGL |
| Peb tsab ntawv ib ntus | Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly- Tyr-Glu-Val-His-His-Gln-Lys-Leu-Va l-Ph-Ph-Ala-Glu-Asp-Val-Gly-Se r-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu |
| Peptide purity (HPLC, %) | 95%/98% |
| Cov mis mos molecular | C170H253N47O52 |
| Molecular Luj (Da) | 3787.20 |
Product Basic Information Table
|
Khoom Lub Npe Lus Askiv |
Product Abbreviation / Alias |
Function Tags (comma-sib cais) |
Amino Acid Tag Nrho Lub Npe Sequence |
Molecular Formula |
Qhov hnyav Molecular (Da) |
Qhov Nruab Nrab Molecular Luj (Da) |
Terminal Hloov kho - N-terminus |
Terminal Hloov kho - C-terminus |
Qhov ntev (aa) |
|
-Amyloid (1-34) |
#A (1-34) #BACE1 cleavage intermediate fragment; #Alzheimer's tus kab mob biomarker peptide; # Kev tshawb nrhiav cov kab mob metabolic |
Neuropathological marker, BACE1 enzyme substrate, Alzheimer's tus kab mob mechanism, amyloid oligomerization, neurotoxicity, cerebral peptide metabolism |
Aspartic acid-Alanine-Glutamic acid-Phenylalanine-Arginine-Histidine-Aspartic acid-Serine-Glycine-Tyrosine-Glutamic acid-Valine-Histidine-Histidine-Glutamine-Lysine-Leucine-Valine-Phenylalanine-Phenylalanine{{19}Alanine{19} acid-aspartic acid-Valine-Glycine-Serine-Asparagine-Lysine-Glycine-Alanine-Isoleucine-Isoleucine{{31}{31}Glycly |
C₁₇₀H₂₅₃N₄₇O₅₂ |
3785.862 |
3787.2 |
Tsis hloov |
Dawb carboxyl pawg |
34 |
Physicochemical Solubility & Cia Parameters
|
Khoom Code |
Qhov tshwm sim |
Pom zoo Dissolution Protocol (los ntawm hnyav) |
Solubility Reference |
Tsis pom zoo Solvents |
Ntev - Lub Sij Hawm Cia Cov Cai |
Luv luv -Lub Sijhawm Cia Cia |
Kua Stability |
Khoom hmoov ruaj khov |
Muaj feem xyuam pH Range |
|
PEB-A 034 |
Dawb lyophilized hmoov |
Dilute acetic acid, dej ultrapure; Tsawg solubility hauv dej nruab nrab, ntxiv glacial acetic acid los txhim kho solubility |
Ntau dua lossis sib npaug li 10mg / mL hauv 0.1% aqueous acetic acid |
Tsis muaj dej ntshiab, alkane organic solvents |
-20℃, lub teeb - pov thawj kaw, aliquoted, tsis txhob rov khov-thaw |
2-8 degree, siv hauv 1 lub hlis; npaj tshiab ua ntej kev sim |
Ruaj khov rau 24 teev ntawm 4 degree |
3 xyoos ntawm -20 degree, 2 xyoos ntawm 4 degree |
3.0-7.0 |
Functional Description
|
Khoom Code |
Frontend Short Summary (rau cov npe tshawb nrhiav) |
Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg |
Cov Cheeb Tsam Tshawb Fawb (comma- cais) |
Hom phiaj / Receptor |
|
PEB-A 034 |
A (1-34) yog soluble intermediate fragment cleaved los ntawm BACE1, core cerebrospinal kua biomarker rau Alzheimer's kab mob |
-Amyloid (1-34) yog lub ntuj soluble peptide tsim los ntawm -secretase BACE1 cleavage ntawm amyloid precursor protein (APP), ib tug tseem ceeb pathological cim nyob rau hauv lub hlwb cov ntaub so ntswg thiab cerebrospinal kua. Nws tsis tuaj yeem sib sau ua ke rau hauv cov neeg laus amyloid fibrils tab sis ua rau kev tsim cov oligomer thaum ntxov, ua rau muaj kev ntxhov siab neuronal oxidative thiab microglia-kev kho mob neuroinflammation. Kev siv dav hauv BACE1 enzyme kev tshuaj ntsuam xyuas, A degradation metabolism, ntxov AD diagnostic biomarker tshawb fawb, neurotoxicity assays thiab anti-Alzheimer tshuaj cell qauv; Feem ntau siv hauv peptidase biochemistry, neuropharmacology thiab kev tshawb fawb biomarker |
Neurobiology, Alzheimer's disease, BACE1 lub hom phiaj tshuaj xyuas tshuaj, cerebrospinal kua biomarker, amyloid metabolism, neuroinflammation |
Amyloid Precursor Protein (APP), -secretase BACE1, microglial TREM2 receptor, neuronal NMDA receptor |
Cov Ntaub Ntawv Tswj Xyuas Zoo
|
Khoom Code |
Purity Detection Method |
Molecular Weight Verification Method |
Kev Tswj Xyuas Qhov Ntsuas |
Impurity Control Standards |
|
PEB-A 034 |
Rov qab-theem HPLC |
ESI-MS Mass Spectrometry |
Purity, dej ntsiab lus, acetate ntsev, hnyav hlau |
Ib qho impurity Tsawg dua lossis sib npaug li 2%, tag nrho impurities Tsawg dua lossis sib npaug li 5% |
SKU Specifications & Inventory Table
|
SKU Unique Code |
Yam khoom Code |
HPLC Purity |
Ntim Specification |
Lub Sijhawm Ua Haujlwm Ntau Lawm |
Customizable |
Optional Custom Modifications |
Cov ntaub ntawv suav nrog |
|
PEB-A 034-98-1 |
PEB-A 034 |
Ntau dua lossis sib npaug li 98% |
1mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Acetylation, amidation, fluorescent labeling, biotin labeling |
CoA, HPLC chromatogram, MS mass spectrum |
|
PEB-A 034-98-5 |
PEB-A 034 |
Ntau dua lossis sib npaug li 98% |
5mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Acetylation, amidation, fluorescent labeling, biotin labeling |
CoA, HPLC chromatogram, MS mass spectrum |
|
PEB-A 034-95-1 |
PEB-A 034 |
Ntau dua lossis sib npaug li 95% |
1mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Acetylation, amidation, fluorescent labeling, biotin labeling |
CoA, HPLC chromatogram, MS mass spectrum |
Cim npe nrov: -amyloid (1-34) cas 186359-65-9, Tuam Tshoj -amyloid (1-34) cas 186359-65-9 manufacturers, lwm tus neeg, Hoobkas
