Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm myr5a peptide hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo myr5a peptide los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | Myr5A peptide |
| Kev piav qhia | Myr5A peptide (Myr5A peptide) yog myristoylated derivative ntawm apolipoprotein A1 (ApoA1) mimetic peptide 5A, ib qho amphipathic -helical lipopeptide. Peptide 5A yog ib qho rationally tsim ApoA1 mimetic peptide muaj li ntawm 22 amino acids, nrog ib tug amphipathic -helical qauv uas mimics lipid{11}}binding thiab reconstituted siab- ntom lipoprotein (rHDL) tsim muaj peev xwm ntawm ApoA1. Myr5A qhia txog hydrophobic lipid tail los ntawm covalently txuas myristic acid (tetradecanoic acid, C14) mus rau sab -chain carboxyl pawg ntawm N-terminal aspartic acid ntawm peptide 5A, tsim ib qho amphipathic molecule tsim los ntawm ib pawg hydrosphoegyl peptide. Circular dichroism (CD) kev ntsuas qhia tias myristic acid conjugation tsis hloov -helical theem nrab qauv ntawm peptide 5A. Hauv cov tshuaj aqueous, Myr5A tuaj yeem ua tus kheej - sib dhos los ntawm kev sib cuam tshuam hydrophobic thiab -helical packing peptide chains los ua discoidal lossis kheej kheej siab- ntom lipoprotein (HDL)-mimetic lipid nanostructures, lipid cores zoo ib yam li cov lipid core. peptide plhaub. Cov HDL-mimetic nanoparticles no tuaj yeem siv los encapsulate hydrophobic tshuaj, tshwj xeeb yog anthracycline chemotherapeutics xws li doxorubicin thiab valrubicin, los ntawm kev sib cuam tshuam ntawm cov tshuaj thiab hydrophobic core ntawm nanoparticle, thiab rau hauv vitro tshuaj tso tawm kev tshawb fawb kinetics. Myr5A tus kheej- sib sau ua ke nanoparticles tuaj yeem siv HDL receptor (xws li SR-BI, ABCA1)-txoj kev kho cov cellular uptake pathways rau lub hom phiaj xa tshuaj, nrog rau cov kev siv hauv kev kho kab mob plawv (xws li kev tiv thaiv-} kab mob qog noj ntshav, cholesterol, kev kho mob. Tsis tas li ntawd, cov fluorescence intrinsic ntawm tryptophan thiab tyrosine residues hauv Myr5A peptide tuaj yeem siv los soj ntsuam cov txheej txheem sib dhos thiab kev hloov pauv ntawm cov nanoparticles. |
| Peptide Purity (HPLC, %) | Ntau dua lossis sib npaug li 95% |
| Cov mis mos molecular | C₂₁₁H₃₂₁N₄₇O₅₇ |
| Molecular Luj (Da) | 4428.09 |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Myr5A peptide | Myristoyl pentaalanine peptide; daim nyias nyias -anchoring peptide Myr5A | Membrane localization peptide, protein membrane anchoring, liposome hloov, cell membrane engineering | N-terminal myristoylated (C14 saturated fatty acid) pentaalanine; myristoyl yog lub ntuj daim nyias nyias- cov pab pawg neeg uas nkag mus rau hauv phospholipid bilayers rau protein anchoring, liposome functionalization thiab membrane engineering | C₂₈H₅₃N₅O₆ | 555.4 | ~555.7 | Dawb peptide (lipid{0}} hloov kho) | 5 (pentapeptide + myristoyl) |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-MY5001 | Dawb rau tawm -dawb crystalline hmoov | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau shipping ntawm ambient kub. | ruaj khov rau 7 hnub ntawm 4 degree. Lipid- hloov pauv peptide yog soluble hauv chloroform, DMSO, ethanol thiab lipid systems. Yuav luag insoluble hauv dej; inserts rau hauv phospholipid bilayers nrog muaj zog membrane- khi kev ua si. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-MY5001 | Myristoyl pentapeptide Myr5A, natural membrane thauj tog rau nkoj rau cell membrane & liposome | Myr5A yog myristoylated pentaalanine peptide. Myristoyl yog ib txwm tshwm sim tom qab- kev hloov pauv hauv eukaryotes uas ruaj khov rau hauv phospholipid bilayers los ntawm kev sib cuam tshuam hydrophobic kom ua tiav daim nyias nyias ntawm cov proteins lossis nanoparticles. Nws yog dav siv nyob rau hauv protein membrane localization hloov kho, liposome nto functionalization, cell membrane engineering thiab membrane protein reconstitution research. | Cell membrane engineering, protein lipid hloov kho, liposome technology, membrane protein kev tshawb fawb, biomembrane biomimetics | Phospholipid bilayer hydrophobic insertion; kev hloov kho ntawm daim nyias nyias; liposome nto functionalization |
Cim npe nrov: myr5a peptide, Tuam Tshoj myr5a peptide manufacturers, lwm tus neeg, Hoobkas
