Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov chaw muag khoom ntawm tat-peptide 190-208 tfa hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau kev lag luam wholesale bulk zoo tat-peptide 190-208 tfa los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | Tat-peptide 190-208 TFA |
| Kev piav qhia | Tat-peptide 190-208 TFA yog ib qho hluavtaws peptide sib raug rau cov seem 190–208 cheeb tsam (nrog txuas txuas ntxiv, suav nrog 30 amino acids) ntawm HIV-1 trans- ua kom muaj cov protein ntau, nrog sequence YGNKKNNQNNNVEPEPDPEPEPEQEPVSE, muab ua ib qho ntsev trifluoroacetate (TFA). Tus kab mob HIV-1 Tat protein yog ib qho tseem ceeb transcriptional activator ntawm tus kab mob gene qhia, ua lub luag haujlwm tseem ceeb hauv tus kab mob sib kis thiab kab mob. Cov peptide no yog nplua nuj nyob rau hauv asparagine (N), glutamic acid (E), thiab proline (P) residues, muaj ntau yam sib law liag Glu-Pro (EP) rov units thiab acidic amino acid pawg nrog tag nrho cov nqi tsis zoo, sib xws rau cov qauv nta ntawm C-terminal cheeb tsam ntawm Tat protein. Cov cheeb tsam no koom nrog Tat protein kev sib cuam tshuam nrog cov tswv cuab ntawm cov xov tooj ntawm tes, kev ua haujlwm ntawm immunomodulatory, thiab kev paub txog molecular ntawm tus kab mob-tus tswv interface. Daim ntawv TFA ntsev txhim kho peptide purity stability thiab dej solubility, ua kom yooj yim rau kev sim. Cov peptide no tuaj yeem siv rau hauv kev tshawb fawb txog kab mob HIV, Tat protein cov qauv-kev tsom xam, kev tshawb fawb txog tus kab mob-tus tswv tsev, cov tshuaj tiv thaiv kab mob epitope, thiab kev tsim tshuaj tiv thaiv. |
| Peptide Purity (HPLC, %) | Ntau dua lossis sib npaug li 98% |
| Cov mis mos molecular | C₁₄₂H₂₁₄N₄₀O₅₇·xC₂HF₃O₂ (TFA ntsev; dawb puag C₁₄₂H₂₁₄N₄₀O₅₇) |
| Molecular Luj (Da) | 3393.45 (dawb puag; TFA ntsev molecular hnyav nce nrog TFA molar piv) |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Tat-peptide 190-208 TFA | Tat peptide 190-208; HIV trans-activator peptide; Classic CPP | Cell- nkag mus rau peptide, ua tau zoo heev intracellular xa, gene transfection, nuclear xa, biomacromolecule ntshuam | Arginine-nplua nuj cationic peptide fragment los ntawm HIV-1 Tat trans-activator domain, TFA ntsev; Nws nkag mus rau hauv cov cell thiab nuclear daim nyias nyias ntawm electrostatic kev sib cuam tshuam, xa nucleic acids, proteins thiab tshuaj mus rau hauv cytoplasm thiab nucleus. | C₉₆H₁₆₅N₃₃O₁₅·xTFA | 2095.27 (dawb peptide) | ~ 2096.7 (peptide dawb) | Trifluoroacetate (TFA) | 19 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-TAT002 | Dawb hmoov | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau shipping ntawm ambient kub. | ruaj khov rau 7 hnub ntawm 4 degree. TFA ntsev yog dawb do soluble nyob rau hauv dej, dilute acetic acid thiab acidic buffers. Zoo stability ntawm cationic peptide nyob rau hauv acidic rau nruab nrab tej yam kev mob; tsub nqi neutralization thiab poob kev ua si nyob rau hauv muaj zog alkaline tej yam kev mob. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-TAT002 | Tat peptide 190-208 TFA, muaj txiaj ntsig zoo CPP rau kev xa tawm nuclear ntawm nucleic acids & proteins | Tat peptide yog ib qho ntawm cov xov tooj ntawm tes siv dav tshaj plaws -peptides, muab los ntawm HIV-1 trans- activator protein. Nws cov arginine-nplua nuj muaj zog cationic qauv enables tsis tshua muaj siab transmembrane efficiency thiab mediates nuclear localization, xa cargoes mus rau lub cell nucleus. Nws muaj txiaj ntsig zoo xa cov plasmid DNA, antisense nucleic acids, protein co toxins thiab cov tshuaj tiv thaiv kab mob rau hauv cov hlwb, thiab tau siv dav hauv kev kho noob, kho cov protein thiab kev tshawb fawb txog tshuaj. | Kev xa cov noob & kev kho noob, kev xa cov protein hauv lub cev, kev tshawb fawb tshuaj, CPP thev naus laus zis, kev xa tawm nuclear | Phospholipid bilayer; nuclear localization signal (NLS) txoj kev; endocytosis / direct translocation |
Cim npe nrov: Tuam Tshoj tat-peptide 190-208 tfa manufacturers, lwm tus neeg, Hoobkas
