Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 1251838-01-3 vicatertide hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 1251838-01-3 vicatertide los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 1251838-01-3: Vicatertide |
| Kev piav qhia | Vicatertide yog ib tug tshiab-tiam structurally optimized PTH1 receptor agonist peptide. Nws khi rau cov tshuaj parathyroid hormone 1 receptor (PTH1R) nrog kev sib raug zoo siab thiab ua rau txoj hauv kev qis qis cAMP teeb liab. Kev tswj xyuas tsis tu ncua txhawb nqa osteoblast proliferation thiab tsim cov pob txha, ua rau cov pob txha pob txha muaj zog, thaum tswj cov calcium thiab phosphate thauj hauv lub raum thiab cov hnyuv kom tswj cov ntshav calcium homeostasis. Nrog rau qhov chaw hloov kho, nws nyob rau hauv vivo metabolic ib nrab-lub neej yog ntev dua li PTHrP haiv neeg, nrog cov pob txha muaj zog xaiv cov nqaij mos. Siv rau hauv kev tshawb fawb mechanism ntawm osteoporosis, pob txha metabolic ntshawv siab, parathyroid dysfunction thiab pob txha metabolic peptide tshuaj txhim kho. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Theoretical molecular hnyav (Da) | ~ 4100 (raws li qhov tseeb hluavtaws batch) |
| Hom qauv | Site-modified linear peptide, PTHrP-derived analog |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Hloov kho hom | Ntev (aa) |
| Vicatertide | Vicatertide; PTHrP analog | Kev txhawb nqa pob txha, Calcium-phosphate regulation, PTH1 receptor agonism, Osteoporosis research, Pob txha metabolism, Long-acting peptide | PTHrP homology caj qaum nrog qhov chaw hloov kho rau kev txhim kho receptor affinity thiab metabolic stability | Loj hloov peptide, raug rau cov batch MS | - | ~ 4100 (theoretical) | Amino acid site hloov pauv hloov | ~34 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-VIC001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted; zam rov qab khov-thaw cycles | ruaj khov rau 1 lub hlis ntawm 2-8℃kaw & qhuav; npaj cov tshuaj aqueous tshiab ua ntej siv | ruaj khov rau 7 hnub ntawm 4 degree; ruaj khov rau 1 lub hlis ntawm -20℃hauv aliquots. ** Dej solubility nruab nrab, soluble nyob rau hauv dilute acetic acid los yog weakly acidic tsis **. Cov kev hloov kho ntawm qhov chaw tseem ceeb txhim kho enzymatic tsis kam | ruaj khov rau 3 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-VIC001 | Ntev - ua haujlwm PTH1 receptor agonist peptide uas txhawb nqa pob txha tsim thiab nce BMD nrog kev tswj xyuas tsis tu ncua, tswj cov calcium-phosphate homeostasis | Vicatertide khi PTH1 receptors ntawm osteoblasts thiab lub raum tubular epithelial hlwb nrog kev xaiv siab, ua kom cov G protein-mediated cAMP/PKA teeb liab txoj hauv kev, thiab ua rau cov pob txha metabolic bidirectional: kev tswj xyuas tsis tu ncua feem ntau txhawb nqa osteoblast proliferation thiab sib txawv, txhim kho cov pob txha pob txha, txhim kho cov pob txha pob txha thiab cov pob txha sib txawv. Kev sib txuas tas mus li feem ntau txhawb cov pob txha resorption thiab txhawb cov ntshav calcium. Tom qab kev hloov kho cov qauv, nws evades loj protease cleavage qhov chaw, nrog rau ntev nyob rau hauv vivo ib nrab-lub neej, muaj zog pob txha cov hom phiaj thiab tsawg dua tawm- phiaj cov kev mob tshwm sim tshaj li haiv neeg PTH/PTHrP. | Kev tshawb fawb osteoporosis, Pob txha metabolism mechanism, Calcium-phosphate homeostasis, Parathyroid muaj nuj nqi tshawb fawb, Pob txha pob txha engineering, Peptide tshuaj txhim kho | Parathyroid Hormone 1 Receptor (PTH1R); cAMP/PKA teeb liab txoj kev; Txhim kho pob txha thiab calcium-phosphate metabolism hauv kev tswj hwm txoj hauv kev |
Cim npe nrov: CAS 1251838-01-3 Vicatertide, Tuam Tshoj CAS 1251838-01-3 Vicatertide manufacturers, lwm tus neeg, Hoobkas
