Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 1883548-85-3 txoj kev-181187 oxalate hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 1883548-85-3 txoj kev-181187 oxalate los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 1883548-85-3:WAY-181187 Oxalate hmoov |
| Kev piav qhia | Txoj kev -181187 yog ib qho kev xaiv serotonin 2C (5-HT2C) receptor agonist nrog cov ntshav-hlwb barrier permeability. Nws ua haujlwm hauv nruab nrab 5-HT2C txoj hauv kev los ua kom qab los noj mov, anxiolytic thiab metabolic txhim kho cov teebmeem, nrog rau qhov tsis tshua muaj kev sib raug zoo rau 5-HT2A / 2B receptors. Siv rau hauv kev tshawb fawb mechanism ntawm kev rog, kev ntxhov siab thiab hauv nruab nrab cov hlab ntsha. |
| Purity (HPLC, %) | 95%/98%/99% |
| Cov mis mos molecular | C₂₆H₃₁ClN₂O₆ (monooxalate) |
| Molecular Luj (Da) | 499.00 |
| Daim ntawv ntsev | Monooxalate |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Puv Amino Acid Sequence | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Hom qauv | Daim ntawv ntsev |
| Txoj Kev-181187 oxalate | WAY-181187 oxalate; KEV 181187; CAS Nr .: 1883548-85-3 | 5-HT2C receptor xaiv agonist, Central qab los noj mov, kev tshawb fawb anxiolytic, kev txhim kho metabolic, tsis tshua muaj kab mob plawv, ntshav-hlwb barrier permeable | Indoleethylamine qaum nrog chloro-methoxy hloov, chiral S- teeb tsa | C₂₆H₃₁ClN₂O₆ (monooxalate) | 498.19 | 499 | Me -molecule indole derivative | Monooxalate |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia Cov Cai | Luv -Lub Sijhawm Cia Cov Cai | Kua Stability | Khoom hmoov ruaj khov |
| PEB-WAY001 | hmoov dawb | Khaws ntawm -20 degree, nruj me ntsis tiv thaiv los ntawm lub teeb, kaw thiab qhuav, aliquoted; zam qhov kub thiab txias thiab lub teeb muaj zog | Khoom hmoov ruaj khov rau 1 xyoos ntawm 2-8℃kaw thiab qhuav; cov kev daws teeb meem tau pom zoo kom npaj rau hauv DMSO | ruaj khov rau 72 h ntawm 4℃hauv qhov tsaus ntuj; ruaj khov rau 1 lub hlis ntawm -20℃hauv aliquots. ** Cov dej tsis zoo solubility, me ntsis soluble hauv dej **, DMSO lossis ethanol xav tau rau solubilization. Photooxidation-nrhiav, nruj lub teeb tiv thaiv yuav tsum tau | ruaj khov rau 2 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-WAY001 | Kev xaiv 5-HT2C receptor agonist siab nrog kev noj qab haus huv hauv nruab nrab thiab cov teebmeem anxiolytic, tsis muaj kev mob plawv. | WAY-181187 is a second-generation highly selective 5-HT2C receptor agonist. The chiral S-configuration precisely matches the receptor binding pocket, with Ki ~1 nM for 5-HT2C, >100-fold selectivity over 5-HT2A and >1000-fold dhau 5-HT2B, txo qis kev pheej hmoo ntawm cov hlab plawv thiab cov kev phiv tshwm sim ntawm cov tshuaj 5-HT agonists. Nws nkag mus rau hauv cov ntshav- lub hlwb teeb meem, ua kom 5-HT2C receptors nyob rau hauv lub hypothalamus thiab limbic system, suppresses lub qab los noj mov chaw, txo tus cwj pwm noj, thiab tswj mus ob peb vas-txog neural circuits rau anxiolytic teebmeem. Cov kev tshawb fawb preclinical qhia pom qhov koob tshuaj ntawm lub cev qhov hnyav txo nyob rau hauv cov qauv kev noj zaub mov uas muaj rog rog uas tsis muaj qhov cuam tshuam loj hauv nruab nrab. Nws ua hauj lwm raws li ib tug classic cuab yeej compound rau rog rog mechanism, ntxhov siab vim, 5-HT txoj kev tshawb fawb thiab tshiab central metabolic tshuaj txoj kev loj hlob. | Kev tshawb fawb txog kev rog rog, kev tshawb fawb txog kev ntxhov siab, kev tshawb fawb serotonin txoj hauv kev, kev txhim kho tshuaj CNS, kev noj qab haus huv tswj kev tshawb fawb, kev tshawb fawb kab mob metabolic | 5-Hydroxytryptamine 2C Receptor (5-HT2CR); Central appetite tswj txoj kev; Mood-regulating neural circuits |
Cim npe nrov: CAS 1883548-85-3 way-181187 oxalate, Tuam Tshoj cas 1883548-85-3 way-181187 oxalate manufacturers, lwm tus, Hoobkas
