Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 34765-96-3 alsactide hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 34765-96-3 alsactide los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 34765-96-3: Alsactide |
| Kev piav qhia | Alsactide yog ib qho hluavtaws adrenocorticotropic hormone (ACTH) analog. Nws khi nrog siab affinity rau melanocortin 2 receptors (MC2R) thiab sai sai nkoos adrenocortical cortisol secretion, siv nyob rau hauv kev kuaj mob ntawm adrenocortical insufficiency thiab hypothalamic-pituitary-adrenal axis mechanism tshawb fawb. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Cov mis mos molecular | C₁₀₁H₁₅₈N₃₀O₂₆S |
| Molecular Luj (Da) | 2178.60 |
| Terminal hloov kho | C-terminal amidation |
Khoom Description
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Tag Nrho Amino Acid Sequence | Molecular Formula | Exact Mass (Da) | Nruab nrab MW (Da) | N-Terminal Hloov kho | C-Terminal Hloov kho | Qhov ntev (aa) |
| Alsactide | Alsactide; ACTH(1-18) analog; Adrenal muaj nuj nqi diagnostic peptide; CAS Nr .: 34765-96-3 | MC2R receptor agonist, Adrenocortical function diagnosis, HPA axis kawm, Cortisol secretion stimulation, Luv -acting diagnostic peptide, Stress mechanism kawm | Serine-tyrosine-serine-methionine-glutamic acid-histidine-phenylalanine-arginine-tryptophan-glycine-lysine-proline-valine-glycine-lysine{1{14} arginine{14} arginides | C₁₀₁H₁₅₈N₃₀O₂₆S | 2177.18 | 2178.6 | Dawb amine, tsis muaj kev hloov kho | Amidation | 18 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia Cov Cai | Luv -Lub Sijhawm Cia Cov Cai | Kua Stability | Khoom hmoov ruaj khov |
| PEB-ALS001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, khaws cia hauv nitrogen hauv aliquots; tsis txhob rov qab khov-thaw cycles thiab muaj zog oxidizing tus neeg sawv cev | Khoom hmoov ruaj khov rau 2 xyoos ntawm 2-8℃kaw thiab qhuav; npaj cov tshuaj aqueous tshiab ua ntej siv | ruaj khov rau 48 h ntawm 4 degree; ruaj khov rau 2 lub lis piam ntawm -20℃hauv aliquots. ** Cov dej zoo solubility, dawb do soluble hauv dej thiab acidic tsis **. Methionine residue muaj oxidative inactivation. Linear luv peptide yooj yim degraded los ntawm peptidases nrog kev ua kom sai sai ntawm chav tsev kub | Ruaj khov rau 3 xyoos ntawm -20℃nyob rau hauv qhuav, tsaus nti & nitrogen cua |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-ALS001 | Luv - ua yeeb yam ACTH analog uas tshwj xeeb qhib MC2 receptor los txhawb cortisol secretion rau kev kuaj mob qog noj ntshav | Alsactide yog ib qho hluavtaws 18-peptide ua kom zoo raws li thaj chaw tseem ceeb ntawm cov haiv neeg ACTH. Nws khaws cia ua tiav MC2 receptor binding thiab agonistic ua haujlwm, thaum tshem tawm cov tsis yog - qhov tseem ceeb ua ntu zus kom sai dua hauv vivo pib thiab tswj tau ntau dua cov metabolism. Nws tshwj xeeb khi rau MC2 receptors ntawm adrenocortical cell membranes, activates cAMP/PKA signaling pathway, thiab sai sai txhawb cov cholesterol hloov mus rau cortisol, nce ntshav cortisol. Cov peptide no yog cov tshuaj ntsuam xyuas classic rau adrenocortical insufficiency, ntsuas adrenal cia ua haujlwm los ntawm kev hloov ntshav cortisol tom qab txhaj tshuaj. Nws kuj tseem siv dav hauv kev tshawb fawb txog kev tswj hwm HPA axis, kev ntxhov siab, thiab adrenal physiology thiab pathology. | Adrenal function diagnosis research, HPA axis regulation study, Stress physiology study, Adrenocortical mechanism research, Kev tshawb fawb endocrine pharmacology, Kev tshawb fawb txog tshuaj hormone secretion regulation | Melanocortin 2 Receptor (MC2R); cAMP/PKA teeb liab txoj kev; Adrenocortical steroid hormone synthesis txoj kev |
Cim npe nrov: CAS 34765-96-3 Alsactide, Tuam Tshoj CAS 34765-96-3 Alsactide manufacturers, lwm tus neeg, Hoobkas
