Shanghai Sunite Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm bcma72-80 cas 2293841-58-2 hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau kev lag luam wholesale bulk zoo bcma72-80 cas 2293841-58-2 los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS Nr .: 2293841-58-2; BCMA72-80 |
| Ib ntus | YLMFLLRKI |
| Peb tsab ntawv ib ntus | Tyr-Leu-Met-Phe-Leu-Leu-Arg-Lys-Ile |
| Peptide purity (HPLC, %) | 95%/98% |
| Cov mis mos molecular | C59H97N13O11S |
| Molecular Luj (Da) | 1196.55 |
Product Basic Information Table
|
Khoom Lub Npe Lus Askiv |
Product Abbreviation / Alias |
Function Tags (comma-sib cais) |
Amino Acid Tag Nrho Lub Npe Sequence |
Molecular Formula |
Qhov hnyav Molecular (Da) |
Qhov Nruab Nrab Molecular Luj (Da) |
Terminal Hloov kho - N-terminus |
Terminal Hloov kho - C-terminus |
Qhov ntev (aa) |
|
PIB (72-80) |
#BCMA72-80 #BCMA qog antigen epitope; #CAR-T phiaj peptide; #MHC chav kawm kuv txwv CTL epitope |
Tumor immunodominant epitope, BCMA targeted therapy, multiple myeloma, CD8+ T cell activation, in vitro CAR-T screening, anti-mob tshuaj tiv thaiv kab mob |
Leucine-Arginine-Glutamine-Tryptophan-Isoleucine-Aspartic acid-Proline-Glutamine-Valine |
C₅₃H₈₄N₂₀O₁₃ |
1244.647 |
1245.36 |
Tsis hloov |
Dawb carboxyl pawg |
9 |
Physicochemical Solubility & Cia Parameters
|
Khoom Code |
Qhov tshwm sim |
Pom zoo Dissolution Protocol (los ntawm hnyav) |
Solubility Reference |
Tsis pom zoo Solvents |
Ntev - Lub Sij Hawm Cia Cov Cai |
Luv luv -Lub Sijhawm Cia Cia |
Kua Stability |
Khoom hmoov ruaj khov |
Muaj feem xyuam pH Range |
|
PEB-BCMA01 |
Dawb lyophilized hmoov |
Dilute acetic acid, dej ultrapure; Tsawg solubility nyob rau hauv nruab nrab cov dej ntshiab, ntxiv glacial acetic acid los txhim kho solubility |
Ntau dua lossis sib npaug li 10mg / mL hauv 0.1% aqueous acetic acid |
Tsis muaj dej ntshiab, alkane organic solvents |
-20 degree, kaw kom deb ntawm lub teeb, aliquoted, tsis txhob rov khov-thaw |
2-8 degree, siv hauv 1 lub hlis; npaj tshiab ua ntej kev sim |
Ruaj khov rau 24 teev ntawm 4 degree |
3 xyoos ntawm -20 degree, 2 xyoos ntawm 4 degree |
3.0-7.0 |
Functional Description
|
Khoom Code |
Frontend Short Summary (rau cov npe tshawb nrhiav) |
Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg |
Cov Cheeb Tsam Tshawb Fawb (comma- cais) |
Hom phiaj / Receptor |
|
PEB-BCMA01 |
BCMA (72-80) yog myeloma- tshwj xeeb MHC-Kuv qog epitope rau hauv vitro functional validation ntawm BCMA CAR-T thiab anti-tumor tiv thaiv kev tshawb fawb |
BCMA (72-80) yog ib qho immunodominant nonapeptide epitope muab los ntawm extracellular domain ntawm B cell maturation antigen, uas ruaj khov khi tib neeg MHC class I molecules thiab tshwj xeeb activates BCMA-reactive CD8⁺ cytotoxic T cells. BCMA yog qhov tshwj xeeb thiab tshwj xeeb tshaj tawm rau ntau lub hlwb qog nqaij hlav myeloma, ua raws li lub hom phiaj tseem ceeb rau CAR-T thiab cov tshuaj tiv thaiv kab mob- tshuaj conjugates. Cov peptide no ua haujlwm raws li tus qauv antigen substrate rau ELISPOT, T cell tua kev soj ntsuam thiab ntws cytometry antigen stimulation. Kev siv dav dav hauv hematological malignancy anti- qog tiv thaiv kab mob, CAR-T kev ntsuas kev ua tau zoo, kev tsim tshuaj tiv thaiv kab mob neoantigen thiab hauv vitro tshuaj ntsuam xyuas ntawm lub cev tiv thaiv kab mob, tsim rau cov qog immunology thiab hematologic oncology kev tshawb fawb tshuaj |
Hematological qog immunology, ntau yam myeloma, BCMA targeted immunotherapy, MHC-I antigen presentation, CTL activation, in vitro CAR-T functional validation |
MHC chav kawm I molecules, CD8⁺ T cell receptor, BCMA- tshwj xeeb TCR / antibody |
Cov Ntaub Ntawv Tswj Xyuas Zoo
|
Khoom Code |
Purity Detection Method |
Molecular Weight Verification Method |
Kev Tswj Xyuas Qhov Ntsuas |
Impurity Control Standards |
|
PEB-BCMA01 |
Rov qab-theem HPLC |
ESI-MS Mass Spectrometry |
Purity, dej ntsiab lus, acetate ntsev, hnyav hlau |
Ib qho impurity Tsawg dua lossis sib npaug li 2%, tag nrho impurities Tsawg dua lossis sib npaug li 5% |
SKU Specifications & Inventory Table
|
SKU Unique Code |
Yam khoom Code |
HPLC Purity |
Ntim Specification |
Lub Sijhawm Ua Haujlwm Ntau Lawm |
Customizable |
Optional Custom Modifications |
Cov ntaub ntawv suav nrog |
|
PEB-BCMA01-98-1 |
PEB-BCMA01 |
Ntau dua lossis sib npaug li 98% |
1mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Acetylation, amidation, fluorescent labeling, biotin labeling |
CoA, HPLC chromatogram, MS mass spectrum |
|
PEB-BCMA01-98-5 |
PEB-BCMA01 |
Ntau dua lossis sib npaug li 98% |
5mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Acetylation, amidation, fluorescent labeling, biotin labeling |
CoA, HPLC chromatogram, MS mass spectrum |
|
PEB-BCMA01-95-1 |
PEB-BCMA01 |
Ntau dua lossis sib npaug li 95% |
1mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Acetylation, amidation, fluorescent labeling, biotin labeling |
CoA, HPLC chromatogram, MS mass spectrum |
Cim npe nrov: bcma72-80 cas 2293841-58-2, Tuam Tshoj bcma72-80 cas 2293841-58-2 manufacturers, lwm tus, Hoobkas
