Shanghai Sunite Biotechnology Co., Ltd. yog ib qho ntawm cov tuam txhab ua lag luam thiab cov chaw muag khoom ntawm -cateninpeptide cas 265669-37-2 hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo-cateninpeptide cas 265669-37-2 los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 265669-}37-2; - cateninpeptide |
| Ib ntus | RTYEKL |
| Peb tsab ntawv ib ntus | Arg-Thr-Tyr-Thr-Tyr-Glu-Lys-Leu |
| Peptide purity (HPLC, %) | 95%/98% |
| Cov mis mos molecular | C49H76N12O15 |
| Molecular Luj (Da) | 1073.2 |
Product Basic Information Table
|
Khoom Lub Npe Lus Askiv |
Product Abbreviation / Alias |
Function Tags (comma-sib cais) |
Amino Acid Tag Nrho Lub Npe Sequence |
Molecular Formula |
Qhov hnyav Molecular (Da) |
Qhov Nruab Nrab Molecular Luj (Da) |
Terminal Hloov kho - N-terminus |
Terminal Hloov kho - C-terminus |
Qhov ntev (aa) |
|
-catenin peptide |
# -catenin(1-19) #Wnt pathway peptide; # -catenin khi substrate; # Kev tshawb nrhiav qog nqaij hlav |
Wnt/ -catenin pathway, cell adhesion, tumorigenesis, transcriptional co-activator, protein sib cuam tshuam, teeb liab transduction |
Alanine-Proline-Leucine-Serine-Serine-Threonine-Serine-Serine-Serine-Proli ne-Proline-Proline-Serine-Serine-Serine-Serine-Serine-Serine-Serine |
C₈₅H₁₄₀N₂₈O₄₃ |
2172.965 |
2174.12 |
Tsis hloov |
Dawb carboxyl pawg |
19 |
Physicochemical Solubility & Cia Parameters
|
Khoom Code |
Qhov tshwm sim |
Pom zoo Dissolution Protocol (los ntawm hnyav) |
Solubility Reference |
Tsis pom zoo Solvents |
Ntev - Lub Sij Hawm Cia Cov Cai |
Luv luv -Lub Sijhawm Cia Cia |
Kua Stability |
Khoom hmoov ruaj khov |
Muaj feem xyuam pH Range |
|
PEB-BCAT01 |
Dawb lyophilized hmoov |
Dilute acetic acid, dej ultrapure; Tsawg solubility nyob rau hauv nruab nrab cov dej ntshiab, ntxiv glacial acetic acid los txhim kho solubility |
Ntau dua lossis sib npaug li 10mg / mL hauv 0.1% aqueous acetic acid |
Tsis muaj dej ntshiab, alkane organic solvents |
-20 degree, kaw kom deb ntawm lub teeb, aliquoted, tsis txhob rov khov-thaw |
2-8 degree, siv hauv 1 lub hlis; npaj tshiab ua ntej kev sim |
Ruaj khov rau 24 teev ntawm 4 degree |
3 xyoos ntawm -20 degree, 2 xyoos ntawm 4 degree |
3.0-7.0 |
Functional Description
|
Khoom Code |
Frontend Short Summary (rau cov npe tshawb nrhiav) |
Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg |
Cov Cheeb Tsam Tshawb Fawb (comma- cais) |
Hom phiaj / Receptor |
|
PEB-BCAT01 |
-catenin peptide yog N-terminal functional fragment of -catenin with multiple Ser/Thr phosphorylation sites, thov rau canonical Wnt pathway thiab qog signaling mechanism research |
-catenin peptide yog 19-residue N-terminal fragment ntawm tib neeg -catenin, enriched nyob rau hauv Ser/Thr phosphorylation motifs lees paub los ntawm glycogen synthase kinase GSK-3 . Unphosphorylated {{9} bins rau hauv CF) transcription yam thiab qhib Wnt hom noob, tswj cov cell proliferation, tsiv teb tsaws thiab intercellular adhesion. Aberrant tsub zuj zuj ua rau cov qog nqaij hlav nrog rau cov kab mob hauv plab thiab hepatocellular carcinoma. Nws ua raws li classic hauv vitro substrate rau GSK-3 kinase assay thiab qauv peptide rau -catenin / APC / Axin kev sib cuam tshuam kev kawm. Dav siv rau Wnt pathway inhibitor kev tshuaj ntsuam, qog molecular mechanism, qia cell sib txawv thiab cell adhesion cell qauv, tsim rau qog pharmacology thiab kev loj hlob biology tshawb fawb |
Tumor biology, canonical Wnt signaling pathway, stem cell differentiation, protein kinase substrate, cell adhesion, anti- kuaj mob qog noj ntshav |
GSK-3 , APC, Axin, TCF/LEF transcription factors, -catenin homo-oligomers |
Cov Ntaub Ntawv Tswj Xyuas Zoo
|
Khoom Code |
Purity Detection Method |
Molecular Weight Verification Method |
Kev Tswj Xyuas Qhov Ntsuas |
Impurity Control Standards |
|
PEB-BCAT01 |
Rov qab-theem HPLC |
ESI-MS Mass Spectrometry |
Purity, dej ntsiab lus, acetate ntsev, hnyav hlau |
Ib qho impurity Tsawg dua lossis sib npaug li 2%, tag nrho impurities Tsawg dua lossis sib npaug li 5% |
SKU Specifications & Inventory Table
|
SKU Unique Code |
Yam khoom Code |
HPLC Purity |
Ntim Specification |
Lub Sijhawm Ua Haujlwm Ntau Lawm |
Customizable |
Optional Custom Modifications |
Cov ntaub ntawv suav nrog |
|
PEB-BCAT01-98-1 |
PEB-BCAT01 |
Ntau dua lossis sib npaug li 98% |
1mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Acetylation, amidation, fluorescent labeling, biotin labeling |
CoA, HPLC chromatogram, MS mass spectrum |
|
PEB-BCAT01-98-5 |
PEB-BCAT01 |
Ntau dua lossis sib npaug li 98% |
5mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Acetylation, amidation, fluorescent labeling, biotin labeling |
CoA, HPLC chromatogram, MS mass spectrum |
|
PEB-BCAT01-95-1 |
PEB-BCAT01 |
Ntau dua lossis sib npaug li 95% |
1mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Acetylation, amidation, fluorescent labeling, biotin labeling |
CoA, HPLC chromatogram, MS mass spectrum |
Cim npe nrov: -cateninpeptide cas 265669-}37-2, Tuam Tshoj -cateninpeptide cas 265669-37-2 manufacturers, lwm tus neeg, Hoobkas
