Shanghai Sunite Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm melanotan i acetate cas 1566590-77-9 hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo melanotan i acetate cas 1566590-77-9 los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 1566590-77-9; Melanotan I acetate CAS TSIS TAU |
| Ib ntus | Ac-SYS-{Nle}-EH-{d-Phe}-RWGKPV-NH2 |
| Peb tsab ntawv ib ntus | |
| Peptide purity (HPLC, %) | 95%/98% |
| Cov mis mos molecular | C78H111N21O19.xC2H4O2 |
| Molecular Luj (Da) |
Product Basic Information Table
|
Khoom Lub Npe Lus Askiv |
Product Abbreviation / Alias |
Function Tags (comma-sib cais) |
Amino Acid Tag Nrho Lub Npe Sequence |
Molecular Formula |
Qhov hnyav Molecular (Da) |
Qhov Nruab Nrab Molecular Luj (Da) |
Terminal Hloov kho - N-terminus |
Terminal Hloov kho - C-terminus |
Qhov ntev (aa) |
|
Melanotan kuv acetate |
# Melanotan kuv acetate; CAS 1566590-77-9; MT-Kuv; NDP- -MSH; Afamelanotide; [Nle4,D-Phe7]- -MSH acetate |
Melanocortin receptor agonist, Melanogenesis inducer, Photoprotection, Porphyria tshawb fawb, Cov tawv nqaij xim kev cai, MC1R agonist, Sun- tiv thaiv peptide, Vitiligo qauv kev tshawb fawb |
Acetyl-Ser-Tyr-Ser-Nle-Glu-His-D-Phe-Arg-Trp-Gly-Lys{{12}1}V{13}V |
C₈₀H₁₁₅N₂₁O₂₁ |
1645.83 |
1646.93 |
Acetylation (Ac{0}}) |
C-terminal amidation (-NH₂) |
13 |
Physicochemical Solubility & Cia Parameters
|
Khoom Code |
Qhov tshwm sim |
Pom zoo Dissolution Protocol (los ntawm hnyav) |
Solubility Reference |
Tsis pom zoo Solvents |
Ntev - Lub Sij Hawm Cia Cov Cai |
Luv -Lub Sijhawm Cia Cov Cai |
Kua Stability |
Khoom hmoov ruaj khov |
Muaj feem xyuam pH Range |
|
PEB-MT001 |
Dawb lyophilized hmoov |
Ultrapure dej, PBS (pH7.2), dilute acetic acid; me me ntawm DMSO rau kev pab tshem tawm |
Ntau dua lossis sib npaug li 15 mg / mL (dej / PBS) |
Alkanes, diethyl ether, roj av ether |
-20 degree, kaw thiab lub teeb- pov thawj, aliquot kom tsis txhob rov khov-thaw |
2 ~ 8 degree, siv nyob rau hauv 1 lub hlis, npaj tshiab ua ntej siv |
ruaj khov rau 48 h ntawm 4 degree |
ruaj khov rau 3 xyoos ntawm -20 degree |
5.0~8.0 |
Functional Description
|
Khoom Code |
Frontend Short Summary (rau kev tshawb nrhiav cov npe zaub) |
Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg |
Cov cheeb tsam tshawb fawb (comma- cais) |
Hom phiaj / Receptor |
|
PEB-MT001 |
Melanotan I (Afamelanotide) yog ib qho stabilized hluavtaws analog ntawm -MSH, muaj zog xaiv MC1R agonist uas ua rau melanin synthesis thiab daim tawv nqaij photoprotection rau porphyria & pigmentation teeb meem mechanism kawm |
Melanotan I acetate (Afamelanotide / NDP- -MSH) yog hloov kho 13-amino-acid melanocyte-stimulating hormone analog. Qhov chaw hloov pauv Nle4 & D-Phe7 ua rau txhim kho metabolic stability thiab receptor affinity vs haiv neeg -MSH. Nws xaiv activates melanocortin 1 receptor (MC1R) ntawm melanocytes los txhim kho tyrosinase qhia, txhawb melanin ntau lawm thiab tso nyiaj, txhim kho UV photoprotection ntawm daim tawv nqaij. Nws kuj modulates MC4R los tswj lub zog metabolism thiab kev tiv thaiv kab mob. Dav siv nyob rau hauv erythropoietic protoporphyria phototoxicity tiv thaiv, vitiligo, pigmentation teeb meem, UV daim tawv nqaij puas qauv, melanocortin GPCR tshuaj, photoprotective peptide tshuaj ntsuam xyuas thiab cutaneous immune mechanism kev tshawb fawb. |
Dermatopharmacology, melanocyte biology, kev tshawb fawb photoprotection, tus qauv kab mob porphyria, pigmentation tsis meej, GPCR pharmacology, hnub- tshuaj tiv thaiv peptide, o thiab kev tshawb fawb tiv thaiv kab mob |
Melanocortin receptor MC1R (thawj); MC3R, MC4R, MC5R |
Cov Ntaub Ntawv Tswj Xyuas Zoo
|
Khoom Code |
Purity Detection Method |
Molecular Weight Verification Method |
Kev Tswj Xyuas Qhov Ntsuas |
Impurity Control Standards |
|
PEB-MT001 |
HPLC High Performance Liquid Chromatography |
ESI-MS Mass Spectrometry |
Purity, dej ntsiab lus, Acetate, Heavy hlau, Residual hnyav |
Ib qho impurity Tsawg dua lossis sib npaug li 2%, Tag nrho cov impurities Tsawg dua lossis sib npaug li 5% |
SKU Specifications & Inventory Table
|
SKU Unique Code |
Yam khoom Code |
HPLC Purity |
Ntim Specification |
Lub Sijhawm Ua Haujlwm Ntau Lawm |
Customizable |
Optional Custom Modifications |
Cov ntaub ntawv suav nrog |
|
PEB-MT001-98-1 |
PEB-MT001 |
Ntau dua lossis sib npaug li 98% |
1mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Biotin labeling, Fluorescent labeling, Isotope labeling, Terminal modification |
CoA, HPLC spectrum, MS huab hwm coj spectrum |
|
PEB-MT001-98-5 |
PEB-MT001 |
Ntau dua lossis sib npaug li 98% |
5mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Biotin labeling, Fluorescent labeling, Isotope labeling, Terminal modification |
CoA, HPLC spectrum, MS huab hwm coj spectrum |
|
PEB-MT001-95-1 |
PEB-MT001 |
Ntau dua lossis sib npaug li 95% |
1mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Biotin labeling, Fluorescent labeling, Isotope labeling, Terminal modification |
CoA, HPLC spectrum, MS huab hwm coj spectrum |
Cim npe nrov: Tuam Tshoj melanotan i acetate cas 1566590-77-9 manufacturers, lwm tus neeg, Hoobkas
