Shanghai Sunite Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm melanotan ii cas 121062-08-6 hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo melanotan ii cas 121062-08-6 los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 121062-08-6; Melanotan (MT)-II |
| Ib ntus | Ac-{Nle}-DH-{d-Phe}-RWK-NH2, (2→7)-lactam |
| Peb tsab ntawv ib ntus | Ac-{Nle}-Asp-Nws-{d-Phe}-Arg-Trp-Lys-NH2, (2→7)-lactam |
| Peptide purity (HPLC, %) | 95%/98% |
| Cov mis mos molecular | C50H69N15O9 |
| Molecular Luj (Da) | 1024.18 |
Product Basic Information Table
|
Khoom Lub Npe Lus Askiv |
Product Abbreviation / Alias |
Function Tags (comma-sib cais) |
Amino Acid Tag Nrho Lub Npe Sequence |
Molecular Formula |
Qhov hnyav Molecular (Da) |
Qhov Nruab Nrab Molecular Luj (Da) |
Terminal Hloov kho - N-terminus |
Terminal Hloov kho - C-terminus |
Qhov ntev (aa) |
|
Melanotan II |
#Melanotan II; CAS 121062-08-6; MT-II; Cyclic melanotropic peptide; Melanogenesis agonist peptide |
Melanocortin dual agonist MC1R / MC4R, Melanin synthesis inducer, Photoprotection, Appetite regulation, Sexual function modulation, Skin pigmentation model, GPCR peptide kev tshawb fawb |
Acetyl-Nle-His-D-Phe-Arg-Trp-Lys-Pro-amide, intramolecular cyclization ntawm thioether bond ntawm Lys1 & Asp4 |
C₅₀H₆₉N₁₅O₉S |
1023.51 |
1024.24 |
Acetylation (Ac{0}}) |
C-terminal amidation (-NH₂) |
7 |
Physicochemical Solubility & Cia Parameters
|
Khoom Code |
Qhov tshwm sim |
Pom zoo Dissolution Protocol (los ntawm hnyav) |
Solubility Reference |
Tsis pom zoo Solvents |
Ntev - Lub Sij Hawm Cia Cov Cai |
Luv -Lub Sijhawm Cia Cov Cai |
Kua Stability |
Khoom hmoov ruaj khov |
Muaj feem xyuam pH Range |
|
PEB-MT2001 |
Dawb lyophilized hmoov |
Dilute acetic acid, dej ultrapure, nruab nrab PBS tsis; Cov dej solubility zoo heev, dilute acetic acid txhim kho lub sijhawm ntev - kua stability |
Ntau dua lossis sib npaug li 12 mg / mL (dej / PBS) |
Alkanes, roj av ether, diethyl ether organic solvents |
-20 degree, kaw thiab lub teeb- pov thawj, aliquot kom tsis txhob rov khov-thaw |
2 ~ 8 degree, siv nyob rau hauv 1 lub hlis, npaj tshiab thiab tsis muaj menyuam - lim nrog 0.22μm membrane |
ruaj khov rau 48 h ntawm 4 degree |
ruaj khov rau 3 xyoos ntawm -20 degree |
4.5~8.0 |
Functional Description
|
Khoom Code |
Frontend Short Summary (rau cov npe tshawb nrhiav) |
Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg |
Cov cheeb tsam tshawb fawb (comma- cais) |
Hom phiaj / Receptor |
|
PEB-MT2001 |
Melanotan II yog cyclized -MSH heptapeptide analog, muaj zog dual agonist ntawm MC1R & MC4R, nrog rau ob qho kev ua ub no suav nrog kev txiav melanogenic photoprotection thiab hauv nruab nrab qab los noj mov / kev sib deev muaj nuj nqi, universal tool peptide rau pigment & neuroendocrine kev tshawb fawb |
Melanotan II yog ib qho khoom siv dag zog ua kom ruaj khov ntawm -MSH, tsim intramolecular thioether cyclic skeleton nrog 7 amino acids. Kev hloov kho dual davhlau ya nyob twg (N-Acetylation + C-amidation) siab tiv thaiv peptidase degradation nyob rau hauv vivo, nrog rhiab heev receptor affinity tshaj haiv neeg -MSH. Nws exerts dual biological teebmeem ntawm txawv txoj kev: 1. Peripheral daim tawv nqaij ua ntawm MC1R: Activates tyrosinase boost melanin synthesis thiab deposition, pab txhawb UV photoprotection, lug siv nyob rau hauv pigmentation teeb meem, vitiligo thiab UV daim tawv nqaij puas qauv; 2. Kev ua haujlwm hauv nruab nrab ntawm MC4R: Modulates hypothalamic qab los noj mov qhov chaw txhawm rau txo qis kev noj zaub mov, lub sijhawm no tswj kev sib deev -txog neuro circuits rau kev tshawb fawb neuroendocrine. Dav siv nyob rau hauv dermatopharmacology, melanocyte biology, melanocortin GPCR kev tshawb fawb, noj tus cwj pwm & kev rog rog, neuroendocrine peptide pharmacology |
Dermatopharmacology, Melanocyte biology, Kev tshawb fawb Photoprotection, Pigmentation disorder kab mob, Metabolic noj kev cai, Neuroendocrinology, GPCR pharmacology, kev sib deev muaj nuj nqi mechanism kev tshawb fawb |
Melanocortin receptors MC1R, MC4R (thawj); MC3R, MC5R (secondary) |
Cov Ntaub Ntawv Tswj Xyuas Zoo
|
Khoom Code |
Purity Detection Method |
Molecular Weight Verification Method |
Kev Tswj Xyuas Qhov Ntsuas |
Impurity Control Standards |
|
PEB-MT2001 |
HPLC High Performance Liquid Chromatography |
ESI-MS Mass Spectrometry |
Purity, dej ntsiab lus, Acetate, Hnyav hlau, Residual hnyav, Cyclization structural integrity |
Ib qho impurity Tsawg dua lossis sib npaug li 2%, Tag nrho cov impurities Tsawg dua lossis sib npaug li 5% |
SKU Specifications & Inventory Table
|
SKU Unique Code |
Yam khoom Code |
HPLC Purity |
Ntim Specification |
Lub Sijhawm Ua Haujlwm Ntau Lawm |
Customizable |
Optional Custom Modifications |
Cov ntaub ntawv suav nrog |
|
PEP-MT2001-98-1 |
PEB-MT2001 |
Ntau dua lossis sib npaug li 98% |
1mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Biotin labeling, Fluorescent labeling, Isotope labeling, Terminal modification |
CoA, HPLC spectrum, MS huab hwm coj spectrum, Cyclization qauv qhia qhia |
|
PEP-MT2001-98-5 |
PEB-MT2001 |
Ntau dua lossis sib npaug li 98% |
5mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Biotin labeling, Fluorescent labeling, Isotope labeling, Terminal modification |
CoA, HPLC spectrum, MS huab hwm coj spectrum, Cyclization qauv qhia qhia |
|
PEP-MT2001-95-1 |
PEB-MT2001 |
Ntau dua lossis sib npaug li 95% |
1mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Biotin labeling, Fluorescent labeling, Isotope labeling, Terminal modification |
CoA, HPLC spectrum, MS huab hwm coj spectrum, Cyclization qauv qhia qhia |
Cim npe nrov: melanotan ii cas 121062-08-6, Tuam Tshoj melanotan ii cas 121062-08-6 manufacturers, lwm tus, Hoobkas
