Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm dag peptide hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo siab peptide los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | DAG peptide |
| Kev piav qhia | DAG peptide (DAG peptide), nrog cov kab ke Cys-Asp-Ala-Gly-Arg-Lys-Gln-Lys-Cys (CDAGRKQKC), yog ib qho nonapeptide cyclized los ntawm kev sib koom ua ke. Nws muaj ib qho cysteine residue ntawm txhua tus N- thiab C-termini, uas nws pawg thiol oxidize los ua Cys1-Cys9 intramolecular disulfide daim ntawv cog lus, txwv tsis pub cov kab peptide saw txuas mus rau hauv ib qho kev ruaj khov cyclic conformation. Disulfide cyclization ho txhim kho peptide metabolic stability (tsis kam mus rau proteolytic degradation), receptor binding affinity, thiab conformational homogeneity, thiab yog ib tug nquag siv tswv yim nyob rau hauv cyclic peptide tshuaj tsim. DAG peptide muaj ntau hom amino acid muaj pes tsawg leeg: nws muaj ob qho yooj yim amino acids (arginine Arg, ob lysines Lys) nrog rau tag nrho cov nqi zoo, yooj yim khi rau cov cell membranes lossis receptors tsis zoo; ib qho acidic amino acid (aspartic acid Asp) muab cov nqi tsis zoo thiab cov neeg txais nyiaj hydrogen; glycine (Gly) muab kev hloov pauv yooj yim; glutamine (Gln) muab cov hlua khi sab qaum teb; alanine (Ala) koom nrog hydrophobic kev sib cuam tshuam raws li hydrophobic residue. Qhov kev sib xyaw ua ke ntawm zwitterionic thiab multifunctional pawg muab nws cov dej solubility zoo thiab biocompatibility. DAG peptide tuaj yeem siv rau hauv cov protein- kev tshawb fawb ntawm cov protein sib cuam tshuam (PPI), kev nkag mus ntawm tes thiab kev tshawb fawb endosomal khiav, cov neeg xa tshuaj tsom mus rau cov neeg nqa tshuaj, tsim qauv ntawm tes-peptide (CPP), thiab tshuaj peptide tshuaj lead compound tshuaj ntsuam. |
| Peptide Purity (HPLC, %) | Ntau dua lossis sib npaug li 98% |
| Cov mis mos molecular | C₃₈H₆₇N₁₅O₁₃S₂ |
| Molecular Luj (Da) | 1006.16 |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| DAG peptide | DAG daim tawv nqaij tiv thaiv peptide; Antimicrobial peptide DAG | Antimicrobial kho peptide, kho daim tawv nqaij barrier, tiv thaiv -inflammatory soothing, microbiota regulation, kho pob txuv | Endogenous daim tawv nqaij antimicrobial peptide ntawm tsev neeg defensin; cuam tshuam cov kab mob membrane permeability, inhibits pathogen colonization, thiab tswj inflammatory factor tso tawm los txhawb epidermal barrier kho | C₃₃H₅₈N₁₀O₇ | 706.44 | ~707.0 | Acetate | 7 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-DAG001 | Dawb hmoov | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau shipping ntawm ambient kub. | ruaj khov rau 7 hnub ntawm 4 degree. Dawb soluble hauv dej, dilute acetic acid thiab acidic buffers. Zoo stability nyob rau hauv acidic rau nruab nrab tej yam kev mob; rhiab heev rau kub thiab muaj zog lub teeb. Npaj tshiab ua ntej siv. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-DAG001 | DAG daim tawv nqaij tiv thaiv peptide, endogenous antimicrobial peptide rau kev kho thiab tiv thaiv -mob | DAG peptide yog endogenous daim tawv nqaij tiv thaiv antimicrobial peptide thiab ib qho tseem ceeb ntawm daim tawv nqaij tiv thaiv kab mob. Nws ncaj qha cuam tshuam cov kab mob hauv daim nyias nyias, inhibits colonization ntawm daim tawv nqaij kab mob xws li Cutibacterium acnes thiab Staphylococcus aureus, thiab tswj cov kab mob inflammatory hauv keratinocytes. Nws tseem txhawb nqa cov kab mob lipid thiab nruj hlws ris protein synthesis los kho cov tawv nqaij puas, haum rau kev kho pob txuv, kho daim tawv nqaij rhiab thiab kev tshawb fawb qhov txhab. | Kev tshawb fawb ntawm daim tawv nqaij antimicrobial, kho daim tawv nqaij barrier, kho pob txuv kev loj hlob, o kev tswj kev kawm, qhov txhab kho | Cov kab mob membrane permeability; epidermal barrier synthesis txoj kev; inflammatory factor tso tawm txoj kev |
Cim npe nrov: Tuam Tshoj dag peptide manufacturers, lwm tus neeg, Hoobkas
