Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm cas 2159055-74-8 fr -targeting peptide c7 hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 2159055-74-8 fr -targeting peptide c7 los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | FR -tig peptide C7 |
| Kev piav qhia | FR -targeting peptide C7 (FR -targeting peptide C7), CAS 2159055-74-8, nrog rau kab ke Ntsib-Nws-Thr-Ala-Pro-Gly-Trp-Gly-Tyr-Arg-Leu-Ser (MHTAPGW12}}Aminic acid, FRS, xaiv peptide ligand txheeb xyuas los ntawm phage zaub technology. FR yog glycosylphosphatidylinositol (GPI)-anchored cell membrane protein nrog kev txwv tsis pub nyob rau hauv cov ntaub so ntswg ib txwm (feem ntau yog faib rau hauv lub raum proximal tubules, choroid plexus, thiab ntsws), tab sis ho overexpressed nyob rau hauv ntau yam malignancies (xws li zes qe menyuam, mis, mob qog noj ntshav), thiab ua rau endometrium. qog{23}}kev kho mob thiab kev kuaj mob. C7 peptide tshwj xeeb khi cov ligand-binding domain ntawm FR receptor, xaiv paub thiab khi FR -kev nthuav tawm cov qog hlwb, thiab nthuav tawm cov qog- phiaj xwm ntxiv rau hauv vivo. Piv nrog rau cov tshuaj folic acid tsom ligands, C7 peptide muaj ntau dua FR subtype selectivity, qis immunogenicity, zoo dua dej solubility, thiab yooj yim functionalization. Cov peptide muaj cov ntxhiab tsw qab xws li tryptophan (Trp) thiab tyrosine (Tyr), koom nrog kev khi nrog receptor hydrophobic hnab tshos; arginine (Arg) muab cov nqi zoo thiab kev sib cuam tshuam hydrogen; histidine (Nws) tuaj yeem koom nrog hauv pH-kev sib txuas lus teb. C7 peptide tuaj yeem siv rau hauv qog- cov tshuaj xa mus rau cov tshuaj (xws li tshuaj tiv thaiv kab mob- tshuaj conjugates, peptide-drug conjugates, nanomedicines), qog imaging probes (fluorescence, radionuclide, MRI), qog diagnostic reagent kev loj hlob, thiab FR -mediaway. |
| Peptide Purity (HPLC, %) | Ntau dua lossis sib npaug li 98% |
| Cov mis mos molecular | C₆₂H₉₀N₁₈O₁₆S |
| Molecular Luj (Da) | 1375.55 |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| FR -tig peptide C7 | FR - phiaj peptide C7; FR khi peptide; qog aiming peptide | Cov qog nqaij hlav peptide, FR tshwj xeeb khi, kev xa tshuaj, kev kuaj qog, tus neeg saib xyuas mob | Functional peptide uas tshwj xeeb khi folate receptor (FR), uas yog overexpressed ntawm zes qe menyuam, mob ntsws thiab lub mis; Kev kho kom haum xeeb tsom xa cov kws khomob khomob, cov tshuaj ntsuam xyuas thiab cov nanoparticles rau cov qog nqaij hlav | C₃₈H₅₅N₁₁O₉ | 809.41 | ~810.0 | Acetate | 7 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-FRA007 | Dawb hmoov | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau shipping ntawm ambient kub. | ruaj khov rau 7 hnub ntawm 4 degree. Acetate ntsev yog dawb do soluble hauv dej, dilute acetic acid thiab PBS. Kev ua haujlwm zoo khi ntawm lub cev pH; nws yooj yim rau unfolding thiab inactivation nyob rau hauv muaj zog alkaline tej yam kev mob. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-FRA007 | FR -targeting peptide C7 tshwj xeeb khi folate receptor rau qog- phiaj xa khoom | FR -targeting peptide C7 yog qhov siab -affinity peptide soj ntsuam tawm tsam folate receptor (FR ). FR yog overexpressed ntawm zes qe menyuam, ntsws thiab lub mis hlav nrog me ntsis qhia nyob rau hauv ib txwm cov ntaub so ntswg. Cov peptide muab cov kws khomob khomob, cov tshuaj tua kabmob thiab cov tshuaj nanomedicines tshwj xeeb rau cov qog nqaij hlav ntawm FR -kev kho mob endocytosis, txhim kho kev ua tau zoo thiab txo cov kev mob tshwm sim, ua lub hom phiaj tseem ceeb rau kev kuaj mob qog noj ntshav thiab kev tshawb fawb kho mob. | Tumor targeted therapy, molecular imaging & Diagnosis, folate receptor research, targeted drug delivery, kev tshawb fawb nanomedicine | Folate receptor (FR); receptor-kev kho mob endocytosis txoj kev; qog- phiaj xa mus |
Cim npe nrov: CAS 2159055-74-8 fr -targeting peptide c7, Tuam Tshoj cas 2159055-74-8 fr -targeting peptide c7 manufacturers, lwm tus neeg, Hoobkas
