Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 3098205-40-1 m2 peptide hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 3098205-40-1 m2 peptide los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | M2 Peptide |
| Kev piav qhia | M2 Peptide (M2 Peptide), CAS 3098205-40-1, nrog ntu Tyr-Trp-Trp-Lys-Val-Gly-Trp-Pro-Asp-Gln-Glu-Tyr-Cys (QPDEYs, amino acids C-terminus tej zaum yuav raug amidated), yog lub hom phiaj peptide tshwj xeeb tsim los rau M2-zoo li qog-sociated macrophages (TAMs). Cov qog nqaij hlav- txuam nrog macrophages yog cov tshuaj tiv thaiv kab mob ntau tshaj plaws hauv cov qog microenvironment, thiab tuaj yeem ua polarized los tiv thaiv- qog M1 hom thiab tiv thaiv kab mob, pro- qog loj hlob thiab metastasis M2 hom. TAMs nyob rau hauv feem ntau cov qog nqaij hlav yog feem ntau M2 hom, tsim ib qho immunosuppressive qog microenvironment los ntawm secreting immunosuppressive cytokines (xws li IL-10, TGF-), txhawb angiogenesis, thiab inhibiting T cell muaj nuj nqi, uas yog ib qho tseem ceeb ntawm kev tiv thaiv kab mob. M2 peptide tshwj xeeb paub txog thiab khi cov cim tshwj xeeb ntawm qhov chaw ntawm M2 macrophages, xa cov tshuaj los yog cuam tshuam me me RNA (siRNA) tsom rau M2-zoo li TAMs, txhawb lawv cov kev rov qab los ntawm kev tiv thaiv kab mob M2 phenotype rau anti-tumor M1 phenotype, yog li hloov kho cov kab mob ntawm cov kab mob hauv lub cev. tiv thaiv kab mob. Cov peptide yog nplua nuj nyob rau hauv aromatic residues xws li tryptophan (3 Trp) thiab tyrosine (2 Tyr), koom nrog hydrophobic kev sib cuam tshuam nrog receptors; lysine (Lys) muab cov nqi zoo thiab thawj qhov chaw amine conjugation; cysteine (Cys) muab thiol rau qhov chaw tshwj xeeb conjugation (xws li kev sib txuas nrog cov tshuaj hloov pauv txiv neej lossis nanoparticles). M2 peptide tuaj yeem siv rau hauv kev tshawb fawb qog tshuaj tiv thaiv kab mob, kev tshawb fawb macrophage polarization mechanism, kev siv tshuaj siv rau kev tsim kho, kev xa tawm siRNA, thiab qog microenvironment txoj cai kev txhim kho. |
| Peptide Purity (HPLC, %) | Ntau dua lossis sib npaug li 98% |
| Cov mis mos molecular | C₈₆H₁₀₆N₁₈O₂₁S (dawb acid form; C-terminal amidated form C₈₆H₁₀₇N₁₉O₂₀S) |
| Molecular Luj (Da) | 1759.93 (dawb acid daim ntawv; C-terminal amidated daim ntawv 1758.95) |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| M2 Peptide | M2 macrophage tsom peptide; M2 receptor khi peptide | Immune targeting peptide, qog microenvironment modulation, tiv thaiv-mob, kev tiv thaiv kab mob, kev kho mob fibrosis | Functional peptide uas tshwj xeeb paub txog M2-hom qog-associated macrophages (TAMs); Lub hom phiaj M2 macrophage nto cov cim kom xa cov immunomodulators thiab tshuaj rau cov qog tiv thaiv kab mob microenvironment tswj | C₄₂H₆₈N₁₂O₉ | 876.52 | ~877.1 | Acetate | 8 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-M2P001 | Dawb hmoov | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau shipping ntawm ambient kub. | ruaj khov rau 7 hnub ntawm 4 degree. Acetate ntsev yog dawb do soluble hauv dej, dilute acetic acid thiab PBS. Zoo stability nyob rau hauv acidic rau nruab nrab tej yam kev mob; Nws yooj yim rau peptide degradation nyob rau hauv muaj zog alkaline ib puag ncig. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-M2P001 | M2 macrophage-targeting peptide modulates qog immune microenvironment rau immunotherapy | M2 peptide yog lub luag haujlwm peptide uas tshwj xeeb paub txog M2-mob qog- txuam nrog macrophages (TAMs), uas yog cov tshuaj tiv thaiv kab mob tseem ceeb hauv cov qog microenvironment uas txhawb kev tiv thaiv kab mob thiab metastasis. Cov peptide lub hom phiaj M2 macrophage nto cov cim kom xa cov immunomodulators, chemotherapeutics thiab siRNA, reprograms macrophage phenotype thiab thim rov qab cov tshuaj tiv thaiv kab mob microenvironment, siv hauv cov qog immunotherapy, anti-fibrosis thiab kev tshawb fawb mob ntev. | Tumor immunotherapy, macrophage reprogramming, tiv thaiv kab mob - targeted xa, anti- kev tshawb fawb fibrosis, kev tshawb fawb mob ntev | M2 macrophage nto markers; qog tiv thaiv kab mob microenvironment tswj; macrophage polarization txoj kev |
Cim npe nrov: CAS 3098205-40-1 m2 peptide, Tuam Tshoj cas 3098205-40-1 m2 peptide manufacturers, lwm tus neeg, Hoobkas
