Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm cas 1187852-48-7 sor-c13 hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau kev lag luam wholesale bulk zoo cas 1187852-48-7 sor-c13 los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 1187852-48-7: SOR-C13 |
| Kev piav qhia | SOR-C13 yog lub hom phiaj tshwj xeeb tridecapeptide tsim los rau sorcin protein. Nws khi cov sorcin protein zoo heev hauv cov qog hlwb nrog kev sib raug zoo siab, thaiv nws txoj kev sib kho calcium teeb liab kev tswj hwm thiab kev siv tshuaj tiv thaiv ntau yam, thim rov qab cov qog hlwb rau cov tshuaj chemotherapeutic, thiab txhim kho cytotoxicity ntawm cov tshuaj chemotherapeutic; Meanwhile, nws inhibits qog cell invasion, migration thiab epithelial-mesenchymal kev hloov, exerting anti-tumor metastasis nyhuv. Nws muaj lub hom phiaj meej thiab tsis tshua muaj cell toxicity. Siv nyob rau hauv cov qog nqaij hlav multidrug tsis kam, qog metastasis mechanism kev tshawb fawb thiab tsom mus rau cov tshuaj tiv thaiv qog peptide. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Theoretical molecular hnyav (Da) | ~ 1500 (raws li qhov tseeb hluavtaws batch) |
| Hom qauv | Linear targeted tridecapeptide, haiv neeg amino acid sequence |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Hloov kho hom | Ntev (aa) |
| SOR-C13 | SOR-C13 peptide; Sorcin tsom peptide | Multidrug resistance reversal, Tumor metastasis inhibition, Sorcin targeting, Anti- qog adjuvant, Chemosensitization, Peptide tshuaj | Linear tridecapeptide qaum nrog optimized sorcin protein binding site | Loj linear peptide, raws li qhov tseeb batch MS | - | ~ 1500 (theoretical) | Native unmodified | 13 |
Physicochemical Solubility & Cia Parameters
| Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted; zam rov qab khov-thaw cycles | ruaj khov rau 2 lub lis piam ntawm 2-8℃kaw & qhuav; ice pob shipping pom zoo | ruaj khov rau 72h ntawm 4 degree; yooj yim degraded thiab inactivated los ntawm peptidases nyob rau hauv chav tsev kub, ** Solubility dej, yuav tsum tau dilute acetic acid los yog PBS tsis rau dissolution **. Linear peptide yooj yim degraded los ntawm cov ntshav proteases | ruaj khov rau 2 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-SOR1301 | Sorcin -Targeted tridecapeptide uas thim rov qab cov qog ntau yam tshuaj tiv thaiv, txhim kho chemosensitivity thiab inhibits qog invasion thiab metastasis | SOR-C13 tshwj xeeb khi sorcin (soluble resistance-related calcium-binding protein) heev nthuav tawm hauv cov qog hlwb, cuam tshuam nrog nws cov kev cai ntawm intracellular calcium homeostasis, thim rov qab cov kev qhia siab ntawm cov tshuaj tiv thaiv cov proteins xws li P-glycomoroprotein, rov ua kom lub hlwb rov ua dua, thiab rov ua kom lub hlwb rov zoo dua exerts chemosensitization thiab multidrug resistance reversal teebmeem; lub caij no, nws inhibits qog cell adhesion, ntxeem tau thiab kev tsiv teb tsaws chaw los ntawm kev thaiv cov sorcin -mediated metastasis-txog txoj kev taw qhia, thiab txo cov qog metastasis thiab colonization. Nws tsuas yog tsom rau sorcin protein ntau heev hauv cov qog hlwb, nrog rau cov cell toxicity tsawg. Ua ke nrog cov tshuaj chemotherapeutic, nws tuaj yeem txhim kho kev ua tau zoo thiab txo cov kev mob tshwm sim. | Tumor multidrug resistance, Tumor metastasis research, Chemosensitization, Calcium-binding protein function, Anti- qog peptides, Targeted drug development | Sorcin (Soluble resistance-related calcium-binding protein); Tumor multidrug resistance txoj kev; Cov qog nqaij hlav invasion thiab metastasis inhibitory txoj kev |
Cim npe nrov: cas 1187852-48-7 sor-c13, Tuam Tshoj cas 1187852-48-7 sor-c13 manufacturers, lwm tus neeg, Hoobkas
