Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 1447799-33-8 reltecimod hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 1447799-33-8 reltecimod los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 1447799-33-8: Reltecimod |
| Kev piav qhia | Reltecimod yog ib tug tshiab-tiam hluavtaws peptide tsom rau txoj kev inflammatory. Nws khi cov receptors tshwm sim ntawm myeloid hlwb 1 (TREM-1) nrog qhov tshwj xeeb siab, thaiv nws cov kev cuam tshuam nrog ligands, inhibits downstream inflammatory signaling pathways xws li NF-κB, txo qis tshaj tawm ntawm pro-inflammatory cytokines xws li TNF-, IL-1 thiab IL-6, thiab alleviates cua daj cua dub thiab cytok. septic shock, tsis cuam tshuam rau lub cev tiv thaiv kab mob ua haujlwm. Siv rau hauv kev tshawb fawb mechanism ntawm tus kab mob hnyav, sepsis, inflammatory kab mob thiab tshiab anti-inflammatory peptide tshuaj txhim kho. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Theoretical molecular hnyav (Da) | ~ 1310 (raws li qhov tseeb hluavtaws batch) |
| Hom qauv | Targeted hluavtaws peptide, TREM-1 pathway inhibitor |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Hom qauv | Hom phiaj |
| Reltecimod | Reltecimod; TREM-1 inhibitory peptide | TREM-1 pathway inhibition, Anti-cytokine cua daj cua dub, Sepsis tshawb fawb, Kev kis mob hnyav, Targeted anti-inflammatory peptide, Kev tiv thaiv kab mob | Linear hluavtaws peptide caj qaum nrog optimized TREM-1 lub hom phiaj khi ib ntus | Loj peptide, raug rau batch MS | - | ~ 1310 (theoretical) | Synthetic tsom peptide | Triggering Receptor Qhia rau Myeloid cells 1 (TREM-1) |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia Cov Cai | Luv -Lub Sijhawm Cia Cov Cai | Kua Stability | Khoom hmoov ruaj khov |
| PEB-REL001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted; zam rov qab khov-thaw cycles | ruaj khov rau 2 lub lis piam ntawm 2-8℃kaw & qhuav; ice pob shipping pom zoo | ruaj khov rau 48 h ntawm 4 degree; ruaj khov rau 2 lub lis piam ntawm -20℃hauv aliquots. ** Cov dej zoo solubility, dawb do soluble hauv dej thiab physiological tsis **. Linear peptide yooj yim degraded los ntawm endopeptidases nrog kev ua kom sai sai ntawm chav tsev kub | ruaj khov rau 2 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-REL001 | TREM-1-tas hom tshuaj tiv thaiv peptide uas thaiv cov kab mob inflammatory cascade thiab alleviates sepsis cytokine cua daj cua dub los tiv thaiv cov ntaub so ntswg | Reltecimod tshwj xeeb khi rau TREM-1 receptors nyob rau saum npoo ntawm cov hlwb myeloid, sib tw thaiv lawv txoj kev khi rau cov ligands endogenous, yog li inhibits lub inflammatory signaling cascade downstream ntawm tus receptor, downregulates lub activation ntawm pro- inflammatory pathways xws li NF-KB thiab MAP cov tshuaj tiv thaiv tseem ceeb. xws li TNF- , IL-1 , IL-6 thiab HMGB1, thiab alleviates cov ntaub so ntswg thiab lub cev puas tsuaj los ntawm cov lus teb inflammatory ntau dhau. Tsis zoo li broad-spectrum anti-inflammatory tshuaj, nws tsuas yog tsom mus rau amplified inflammatory pathways thiab tsis inhibit basal tiv thaiv kab mob, yog li tus kab mob clearance peev tsis cuam tshuam. Nws qhia txog kev tiv thaiv tseem ceeb hauv cov qauv mob hnyav xws li sepsis, septic shock thiab mob ua pa nyuaj. | Kev tshawb fawb txog Sepsis, Cov qauv kab mob hnyav, Cytokine cua daj cua dub mechanism, Kev raug mob hauv nruab nrog cev, Targeted anti-cov tshuaj tiv thaiv, Innate tiv thaiv kab mob | Triggering Receptor Qhia rau Myeloid cells 1 (TREM-1); NF-κB/MAPK inflammatory txoj kev; Inflammatory cascade blockade txoj kev |
Cim npe nrov: CAS 1447799-33-8 reltecimod, Tuam Tshoj cas 1447799-33-8 reltecimod manufacturers, lwm tus, Hoobkas
