Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas: 178823-49-9: tiplimotide hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas: 178823-49-9: tiplimotide los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 178823-49-9: Tiplimotide |
| Kev piav qhia | Tiplimotide yog cov txheej txheem optimized hluavtaws immunoregulatory luv peptide. Nws txhawb thymic T cell sib txawv thiab maturation nrog rau peripheral T cell ua kom thiab proliferation, elevates cellular tiv thaiv kab mob, bidirectionally tswj lub cev tiv thaiv kab mob homeostasis thiab kho immunodeficiency xeev. Siv rau hauv kev tiv thaiv kab mob, kev tiv thaiv kab mob sib kis, kev tshawb fawb thymic function mechanism thiab kev txhim kho immunomodulator. |
| Peptide Purity (HPLC, %) | 95% / 98% / 99% |
| Terminal kev hloov kho | N-terminal acetylation, C-terminal amidation |
| Theoretical molecular hnyav (Da) | ~850 |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | N-Terminal Hloov kho | C-Terminal Hloov kho | Ntev (aa) |
| Tiplimotide | Tiplimotide; T cell activating peptide; Kev tiv thaiv kab mob txhim kho kev tswj hwm peptide | Txhim kho kev tiv thaiv kab mob, T cell ua kom muaj zog, tiv thaiv kab mob tiv thaiv kab mob, tswj kev tiv thaiv kab mob, Thymus kev ua haujlwm, kev txhim kho Immunomodulator | Linear hluavtaws luv peptide qaum nrog optimized T cell activating sequence, davhlau ya nyob twg thaiv kev hloov kho | Loj peptide, tsis muaj qhov me me -molecule mis; raws li qhov tseeb batch MS | - | ~ 850 (theoretical) | Acetylation, tsis muaj amine dawb | Amidation | ~7 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia Cov Cai | Luv -Lub Sijhawm Cia Cov Cai | Kua Stability | Khoom hmoov ruaj khov |
| PEB-TPL001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted; zam rov qab khov-thaw cycles | ruaj khov rau 2 xyoos ntawm 2-8℃kaw & qhuav; npaj cov tshuaj aqueous tshiab ua ntej siv | ruaj khov rau 72 h ntawm 4 degree; ruaj khov rau 1 lub hlis ntawm -20℃hauv aliquots. ** Cov dej zoo solubility, dawb do soluble hauv dej thiab physiological tsis **. Terminal modifications ho txhim kho enzymatic tsis kam. Aromatic residues ua rau photooxidation | ruaj khov rau 3 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-TPL001 | Terminal-hloov immunoregulatory luv peptide uas txhawb nqa T cell ua kom thiab loj hlob, txhim khu kev tiv thaiv ntawm tes thiab bidirectionally tswj kev tiv thaiv kab mob homeostasis | Tiplimotide yog ib qho kev ua kom zoo tshaj plaws hluavtaws immunoregulatory peptide. Nws ua rau thymic lymphocytes thiab peripheral T hlwb, txhawb kev sib txawv ntawm T cell, maturation thiab activation, elevates CD4+/CD8+ T cell ratio thiab cytotoxic T cell tua kev ua, thiab txhim kho cellular tiv thaiv kab mob thiab kev tiv thaiv kab mob kev ua haujlwm. Lub caij no, nws bidirectionally tswj lub cev tiv thaiv kab mob, kho cov kab mob tiv thaiv kab mob, thiab txhim kho lub cev tiv thaiv- kis kab mob thiab tiv thaiv kab mob qog noj ntshav. Piv nrog rau cov thymic peptides ib txwm muaj, nws lub davhlau ya nyob twg thaiv thiab cov amino acid qhov chaw optimization tau txhim kho metabolic stability nrog ntev dua nyob rau hauv vivo ib nrab -lub neej thiab ntau lub cev tiv thaiv kab mob. Cov molecule no tau siv dav hauv kev tshawb fawb xws li cov qauv kev tiv thaiv kab mob, kev tiv thaiv kab mob sib kis, kev tiv thaiv qog nqaij hlav thiab kev ua haujlwm thymus. Nws ua hauj lwm raws li cov cuab yeej tseem ceeb molecule rau immunoregulatory mechanism kev tshawb fawb thiab peptide immunomodulator txoj kev loj hlob. | Kev tshawb fawb txog kev tiv thaiv kab mob, Thymus biology, Immunodeficiency qauv kawm, Kev pab tiv thaiv kab mob, qog tiv thaiv kab mob, txhim kho Immunomodulator | T cell nto receptors; T cell proliferation thiab sib txawv txoj kev; Cellular immune response regulatory txoj kev |
Cim npe nrov: cas: 178823-49-9: tiplimotide, Tuam Tshoj cas: 178823-49-9: tiplimotide manufacturers, lwm tus neeg, Hoobkas
