Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas: 147664-63-9: pexiganan hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas: 147664-63-9: pexiganan los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 147664-63-9: Pexiganan |
| Kev piav qhia | Pexiganan yog ib qho kev ua kom zoo tshaj plaws dav dav -spectrum antibacterial peptide, ib qho derivative ntawm lub ntuj Qav tawv nqaij antimicrobial peptide Magainin II, koom nrog tsev neeg tiv thaiv peptide. Nws cov txiaj ntsig zoo tau txais txiaj ntsig zoo khi rau qhov tsis zoo phospholipid Cheebtsam ntawm cov kab mob ntawm cov kab mob, thiab hydrophobic sab chains ntxig rau hauv cov cell membrane los tsim cov txheej txheem transmembrane pores, cuam tshuam cov cell membrane kev ncaj ncees thiab transmembrane muaj peev xwm, tua cov kab mob sai nrog kev pheej hmoo ntawm cov tshuaj tiv thaiv. Nws muaj cov tshuaj tua kab mob zoo heev tiv thaiv cov kab mob hauv chaw kho mob xws li * Staphylococcus aureus *, * Pseudomonas aeruginosa * thiab * Escherichia coli *, suav nrog ntau hom - tshuaj tiv thaiv kab mob. Nws yog tsuas yog siv rau hauv kev tshawb fawb ntawm cov tshuaj tua kab mob xws li kab mob ntawm daim tawv nqaij, thiab yog cov cuab yeej tseem ceeb peptide rau kev tshawb nrhiav tshuaj tua kab mob peptide thiab tiv thaiv- tshuaj- tiv thaiv kab mob kab mob kev txhim kho tshuaj. |
| Peptide Purity (HPLC, %) | 95% / 98% / 99% |
| Cov mis mos molecular | C₆₆H₁₁₉N₂₁O₁₂ |
| Molecular Luj (Da) | 1378.79 |
| Hom qauv | Linear -helical antimicrobial peptide, dawb daim ntawv / acetate |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Pexiganan | Pexiganan; MSI-78 | Broad -spectrum antimicrobial peptide, anti-MDR cov kab mob, tiv thaiv kab mob peptide, membrane-lytic antibacterial | 12-mer -helical antimicrobial peptide, optimized derivative ntawm Magainin II, amphiphilic cationic qauv, exerts bactericidal kev ua ub no ntawm membrane cuam tshuam | C₆₆H₁₁₉N₂₁O₁₂ | 1377.93 | 1378.79 | Dawb daim ntawv / acetate | 12 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-PEX001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau luv - lub sij hawm shipping ntawm ambient kub. | Nyob ruaj khov rau 14 hnub ntawm 4 degree. Dawb soluble nyob rau hauv acidic aqueous tov thiab dilute acetic acid; zoo solubility nyob rau hauv nruab nrab physiological tsis. Cationic peptide; zam kev sib xyaw nrog cov khoom muaj zog anionic. | ruaj khov rau 3 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-PEX001 | Dav -spectrum cationic antimicrobial peptide nrog cov kab mob sai sai thiab tsis tshua muaj kev pheej hmoo tiv thaiv MDR cov kab mob | Pexiganan yog ib qho kev ua kom zoo tshaj plaws dav dav -spectrum antimicrobial peptide, ib qho derivative ntawm ntuj Qav tawv nqaij antimicrobial peptide Magainin II, koom nrog tsev neeg tiv thaiv peptide. Nws cov txiaj ntsig zoo tau txais txiaj ntsig zoo khi rau qhov tsis zoo them phospholipids ntawm cov kab mob, thiab hydrophobic sab chains ntxig rau hauv cov cell membrane los tsim cov kab mob hauv cov pores, cuam tshuam cov cell membrane kev ncaj ncees thiab transmembrane muaj peev xwm, tua cov kab mob sai. Ua raws li lub cev qauv ntawm cov cell membrane, nws muaj kev pheej hmoo tsawg ntawm inducing kab mob tsis kam. Nws muaj cov tshuaj tua kab mob zoo heev tiv thaiv cov kab mob hauv chaw kho mob xws li * Staphylococcus aureus *, * Pseudomonas aeruginosa * thiab * Escherichia coli *, suav nrog ntau hom - tshuaj tiv thaiv kab mob. Nws yog tsuas yog siv rau hauv kev tshawb fawb txog tshuaj tua kab mob xws li kab mob ntawm daim tawv nqaij, thiab yog cov cuab yeej tseem ceeb peptide rau kev tshawb nrhiav tshuaj tua kab mob peptide thiab tiv thaiv - tshuaj- tiv thaiv kab mob kab mob tshuaj txhim kho. | Antibacterial peptide mechanism kawm, ntau-kev tshawb fawb tshuaj tiv thaiv kab mob kab mob, tshuaj tiv thaiv kab mob -kev txhim kho tshuaj, kev kawm tiv thaiv kev tiv thaiv, kev tshawb fawb ntawm daim tawv nqaij mob | Cov kab mob cell membrane cuam tshuam lub cev; Tus tswv tsev tiv thaiv thiab innate tiv thaiv kab mob |
Cim npe nrov: cas:147664-63-9: pexiganan, Tuam Tshoj cas:147664-63-9: pexiganan manufacturers, lwm tus neeg, Hoobkas
