Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 1686108-82-6 cotadutide hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 1686108-82-6 cotadutide los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 1686108-82-6: Cotadutide |
| Kev piav qhia | Cotadutide yog ib tiam tshiab dual receptor agonist metabolic peptide. Nws tuaj yeem ua rau tib lub sijhawm ua haujlwm GLP-1 receptors thiab glucagon receptors, ua kom muaj kev sib koom ua ke ntawm cov metabolism hauv kev tswj hwm: ua kom GLP-1 receptors rau cov piam thaj-dependently txhawb insulin secretion, txo cov ntshav qabzib, qeeb plab hnyuv, thiab inhibit kev noj zaub mov; activating glucagon receptors los txhawb lub siab gluconeogenesis, txhim kho lipolysis thiab siv zog, thiab txhim kho daim siab rog. Nws sib npaug cov kev ua agonistic ntawm ob qho tib si receptors, txo qhov hnyav thiab txhim kho lub siab tsis muaj dej cawv thaum txo cov ntshav qabzib. Nws yog ib qho cuab yeej txiav peptide rau kev tshawb fawb ntawm cov kab mob metabolic xws li hom 2 mob ntshav qab zib, rog rog thiab NAFLD. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Theoretical molecular hnyav (Da) | ~ 4500 (raws li qhov tseeb hluavtaws batch) |
| Hom qauv | Qhov chaw hloov kho linear ntev peptide, dual receptor agonistic ua haujlwm |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Nruab nrab MW (Da) | Hloov kho hom | Ntev (aa) |
| Cotadutide | Cotadutide; Dual agonist peptide | GLP-1 / glucagon dual agonism, Hypoglycemic yuag poob, Fatty daim siab txhim kho, kab mob metabolic, Dual receptor agonist, Peptide tshuaj | Glucagon-zoo li peptide qaum nrog qhov chaw hloov kho ntsuas qhov kev ua haujlwm receptor dual | Loj hloov pauv peptide, raug rau qhov tseeb batch MS | - | ~ 4500 (theoretical) | Amino acid site hloov pauv hloov | ~40 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-COT001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted; zam rov qab khov-thaw cycles | ruaj khov rau 2 lub lis piam ntawm 2-8℃kaw & qhuav; ice pob shipping pom zoo | ruaj khov rau 7 hnub ntawm 4 degree; maj mam degraded los ntawm peptidases nyob rau hauv chav tsev kub ** Dej solubility, soluble nyob rau hauv dilute acetic acid los yog tsis muaj zog acidic tsis, nws yog ib tug aggregation nyob rau hauv nruab nrab tov **. Kev ruaj ntseg zoo dua li ib txwm glucagon-zoo li peptide tom qab hloov kho | ruaj khov rau 2 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov Cheeb Tsam Tshawb Fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-COT001 | GLP-1R / GCGR dual receptor agonist peptide uas ua haujlwm tswj cov piam thaj thiab lipid metabolism, txo cov ntshav qabzib, txo qhov hnyav thiab txhim kho lub siab rog. | Cotadutide ua kom muaj kev sib koom ua ke ntawm metabolic los ntawm ib txhij ua kom muaj ob G protein-coupled receptors: activates GLP-1 receptors hauv islets thiab gastrointestinal ib ntsuj av, txhawb cov insulin secretion nyob rau hauv ib tug glucagon-dependent yam, inhibits glucagon tso tawm, qeeb plab hnyuv plab, thiab txo cov ntshav qabzib. activates glucagon receptors nyob rau hauv daim siab thiab adipose cov ntaub so ntswg, txhawb lipolysis, nce zog siv, txo hepatic triglyceride deposition, thiab txhim kho hepatic steatosis thiab insulin tsis kam. Ob qhov kev cuam tshuam receptor yog synergistic, ua tiav qhov hnyav poob thiab lub siab metabolic txhim kho thaum tswj cov ntshav qabzib zoo, nrog cov txiaj ntsig zoo dua li ib leeg GLP-1 receptor agonists. | Kev tshawb nrhiav ntshav qab zib hom 2, Kev rog rog thiab poob phaus, Tsis yog- cawv fatty siab, Glucose- kev tswj hwm lipid metabolism, Dual receptor agonists, Metabolic peptide tshuaj | GLP-1 Receptor (GLP-1R) + Glucagon Receptor (GCGR); cAMP/PKA teeb liab txoj kev; Glucose-lipid metabolism thiab kev siv hluav taws xob tswj txoj hauv kev |
Cim npe nrov: CAS 1686108-82-6 cotadutide, Tuam Tshoj cas 1686108-82-6 cotadutide manufacturers, lwm tus, Hoobkas
