Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 258818-34-7 larazotide hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 258818-34-7 larazotide los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 258818-34-7: Larazotide CAS TSIS TAU |
| Kev piav qhia | Larazotide yog ib qho octapeptide plab hnyuv teeb meem tswj tau los ntawm tus kab mob cholera toxin B subunit. Nws tshwj xeeb khi cov zonulin receptor ntawm plab hnyuv epithelial hlwb, blocks zonulin-mediated nruj hlws ris qhib, txo cov hnyuv permeability, thiab kho cov hnyuv ua haujlwm. Nws tuaj yeem txo qhov kev hloov pauv ntawm luminal co toxins, kab mob thiab cov kab mob inflammatory, thiab txhim kho cov tsos mob cuam tshuam nrog kev ua haujlwm ntawm plab hnyuv. Siv rau hauv kev tshawb fawb mechanism thiab kho plab hnyuv peptide tshuaj tsim kho rau kab mob celiac, chim siab plob tsis so tswj syndrome, inflammatory plob tsis so tswj kab mob, kab mob autoimmune thiab lwm yam teb. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Cov mis mos molecular | C₃₄H₅₈N₈O₁₀ |
| Molecular Luj (Da) | 722.88 |
| Hom qauv | Linear octapeptide, nruj hlws ris regulator |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Puv Amino Acid Sequence | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Hloov kho Terminal | Ntev (aa) |
| Larazotide | Larazotide acetate; Tight junction tswj peptide | Txhim kho plab hnyuv teeb meem, Txo cov plab hnyuv permeability, Zonulin thaiv, kev tshawb fawb kab mob Celiac, IBS, plab hnyuv regulator | Gly-Gly-Val-Leu-Val-Gln-Pro-Gln | C₃₄H₅₈N₈O₁₀ | 722.43 | 722.88 | Native dawb termini | 8 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-LRZ001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted; zam rov qab khov-thaw cycles | ruaj khov rau 2 lub lis piam ntawm 2-8℃kaw & qhuav; ice pob shipping pom zoo | ruaj khov rau 48h ntawm 4 degree; yooj yim degraded los ntawm peptidases nyob rau hauv chav tsev kub nrog ceev kev ua ub no, ** zoo solubility dej, dawb soluble nyob rau hauv dej thiab physiological tsis **; ib txwm tsis hloov pauv luv peptide, yooj yim degraded los ntawm aminopeptidases thiab endopeptidases | ruaj khov rau 2 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-LRZ001 | Kev sib tw zonulin- thaiv octapeptide regulator uas kho cov kab mob plab hnyuv, txo permeability thiab txhim kho celiac thiab IBS cov tsos mob | Larazotide ua raws li qhov sib txuas ntawm qhov chaw endogenous zonulin, sib tw khi rau zonulin receptors ntawm lub plab hnyuv epithelial hlwb, inhibits downstream actin rearrangement, thiab tiv thaiv dissociation thiab qhib ntawm nruj hlws ris proteins, yog li stabilizing lub plab hnyuv epithelial nruj hlws ris nyob rau hauv lub peripheral decisive qauv ntawm cov kab mob. luminal cov ntsiab lus. Nws tuaj yeem thaiv cov transepithelial translocation ntawm cov zaub mov antigens, kab mob endotoxins thiab inflammatory yam, thiab alleviate lub zos plab hnyuv siab raum thiab cov kab mob theem nrab inflammatory teb. Tom qab kev tswj hwm qhov ncauj, peptide ua haujlwm hauv zos hauv txoj hnyuv nrog kev nqus dej tsawg, muaj kev nyab xeeb siab thiab tsis muaj kev phiv tshwm sim. | Kev tshawb fawb kab mob Celiac, Irritable plob tsis so tswj syndrome, plab hnyuv barrier muaj nuj nqi, Inflammatory plob tsis so tswj kab mob, autoimmune plab hnyuv raug mob, gastrointestinal kho peptides | Zonulin receptor; Tight junction protein tswj txoj kev; Txoj hnyuv paracellular permeability tswj txoj hauv kev |
Cim npe nrov: CAS 258818-34-7 larazotide, Tuam Tshoj cas 258818-34-7 larazotide manufacturers, lwm tus, Hoobkas
