Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas: 88650-17-3: fx-06 hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas: 88650-17-3: fx-06 los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 88650-17-3: FX-06 |
| Kev piav qhia | FX-06, tseem hu ua fibrin 15-42 peptide, yog ib qho endogenous active peptide muab tau los ntawm fibrinogen degradation. Nws khi nrog qhov tshwj xeeb siab rau lub extracellular domain ntawm endothelial VE -cadherin, stabilizes inter-endothelial junctions, txo vascular to thiab inflammatory cell infiltration. Siv rau hauv vascular endothelial kev tshawb fawb tiv thaiv xws li myocardial infarction, ischemia-reperfusion raug mob thiab hloov khoom nruab nrog cev. |
| Peptide Purity (HPLC, %) | 95% / 98% / 99% |
| Theoretical molecular hnyav (Da) | ~ 2950 (peptide dawb) |
| Hom qauv | Endogenous fibrin - muab tau los ntawm active polypeptide |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Cysteine suav | Qhov ntev (aa) |
| FX-06 | FX-06; Fibrin 15-42 peptide; Endothelial tiv thaiv peptide; CAS Nr .: 88650-17-3 | Endothelial barrier tiv thaiv, Txo vascular to, tiv thaiv -kev raug mob reperfusion, tiv thaiv Myocardial, Organ transplantation kawm, VE-cadherin ligand | Linear peptide muab tau los ntawm cov saw fibrinogen, muaj ib qho cysteine residue | Loj polypeptide, tsis muaj meej me me -molecule mis; raws li qhov tseeb batch MS | - | ~ 2950 (theoretical) | 1 cysteine | 28 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia Cov Cai | Luv -Lub Sijhawm Cia Cov Cai | Kua Stability | Khoom hmoov ruaj khov |
| PEB-FX0601 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted. ** Tsis txhob tiv tauj nrog oxidizing tus neeg sawv cev thiab muaj zog txo cov neeg ua haujlwm ** | Khoom hmoov ruaj khov rau 2 xyoos ntawm 2-8℃kaw thiab qhuav; npaj cov tshuaj aqueous tshiab ua ntej siv | ruaj khov rau 72 h ntawm 4 degree; ruaj khov rau 1 lub hlis ntawm -20℃hauv aliquots. ** Cov dej zoo solubility, dawb do soluble hauv dej thiab physiological tsis **. Ib leeg cysteine prone rau oxidation rau hauv disulfide dimer. Linear ntev peptide yooj yim degraded los ntawm endopeptidases | ruaj khov rau 3 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-FX0601 | Endogenous fibrin- muab tau los ntawm peptide uas khi VE-cadherin kom stabilize endothelial barrier thiab alleviate ischemia-reperfusion raug mob | FX-06 yog ib qho endogenous active peptide tso tawm tom qab fibrinogen hydrolysis los ntawm thrombin thaum lub sij hawm coagulation, ua hauj lwm raws li ib tug natural tiv thaiv qhov chaw ntawm vascular raug mob. Nws khi nrog qhov tshwj xeeb siab rau lub extracellular domain 4 ntawm VE-cadherin ntawm cov kab mob endothelial cell, stabilizes cadherin-mediated intercellular adherens junctions, thiab inhibits cytokine-induced junction dissociation thiab endocytosis endocythel, yog li tswj cov hlab ntsha. edema thiab inflammatory cell infiltration. Hauv ischemia-reperfusion qauv xws li myocardial infarction, cerebral ischemia thiab hloov khoom nruab nrog cev, peptide no tuaj yeem txo cov ntaub so ntswg puas, txo qhov loj me me thiab txhim kho lub cev ua haujlwm. Cov molecule no ua haujlwm zoo li cov cuab yeej tseem ceeb peptide rau endothelial barrier txoj cai tswj kev tshawb fawb mechanism, ischemia-reperfusion raug mob cuam tshuam, vascular tiv thaiv tshuaj txhim kho thiab kev hloov pauv hauv nruab nrog cev tiv thaiv kev ua kom zoo. | Ischemia-Kev tshawb fawb txog kev raug mob, kev tshawb fawb txog kev tiv thaiv Myocardial, kev tshawb fawb txog kev hloov pauv hauv nruab nrog cev, Endothelial barrier mechanism, vascular biology tshawb fawb, Anti- tiv thaiv vascular tiv thaiv | Vascular Endothelial Cadherin (VE{0}}cadherin); Endothelial adherens junction stabilization txoj kev; Vascular to thiab o regulatory pathway |
Cim npe nrov: cas:88650-17-3:fx-06, Tuam Tshoj cas:88650-17-3:fx-06 manufacturers, lwm tus neeg, Hoobkas
