Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas: 69-25-0: eledoisin hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas: 69-25-0: eledoisin los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 69-25-0: Eledoisin |
| Kev piav qhia | Eledoisin yog lub ntuj tsim tachykinin tsev neeg peptide cais tawm ntawm cov qog ntshav qab zib octopus. Nws khi rau neurokinin NK2 thiab NK3 receptors nrog siab affinity, activates G protein-txoj kev taw qhia kev sib kho, ua kom cov calcium nyob rau hauv lub cev, ua kom muaj zog vasodilation thiab hypotensive teebmeem, thiab ib txhij excites ntau yam nqaij nqaij du xws li plab hnyuv thiab ua pa ntawm lub plab zom mov, qog. Nws cov qauv hloov kho tau pom tseeb receptor subtype selectivity, thiab nws yog ib qho cuab yeej classic peptide rau tachykinin receptor function research, cardiovascular pharmacology thiab neuropeptide mechanism research. Nws yog dav siv hauv kev tshawb fawb mechanism hauv kev ua haujlwm ntawm cov leeg nqaij du, glandular secretion, mob thiab mob. |
| Peptide Purity (HPLC, %) | 95% / 98% / 99% |
| Dawb peptide molecular mis | C₅₄H₈₅N₁₃O₁₅S |
| Dawb peptide molecular hnyav (Da) | 1188.40, siab dua rau daim ntawv ntsev |
| Hom qauv | Linear undecapeptide, N-terminal pyroglutamate hloov kho, C-terminal amidation, dawb peptide / acetate / TFA ntsev |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Eledoisin | Eledone peptide; Octopus salivary caj pas peptide | Tachykinin receptor agonist, muaj zog vasodilation, du leeg excitation, secretagogue | Linear undecapeptide nrog N-terminal pyroglutamate (pGlu) thiab C-terminal amidation, ntuj tachykinin tsev neeg peptide | C₅₄H₈₅N₁₃O₁₅S | 1187.6 | 1188.4 | Dawb peptide / TFA ntsev | 11 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-ELE001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot kom tsis txhob rov qab khov-thaw mus. Khaws kom deb ntawm cov kab mob protease. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; nkoj ntawm cov pob khov nab kuab pom zoo. | Ruaj khov rau 7 hnub ntawm 4℃hauv cov kua dej. Muaj kev cuam tshuam rau proteolytic degradation; aliquot sterilely thiab khaws cia ntawm -20℃tom qab reconstitution. Solubility: ~ 15 mg / mL hauv DMF, ~ 20 mg / mL hauv DMSO, ~ 0.04 mg / mL hauv DMSO: PBS (pH 7.2, 1: 20). | ruaj khov rau 3 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-ELE001 | Ntuj tachykinin peptide, siab -kev ua agonist ntawm NK2 / NK3 receptors, muaj zog vasodilator | Eledoisin yog ib qho ntuj tachykinin undecapeptide cais tawm los ntawm octopus salivary qog. Nws khi neurokinin NK2 thiab NK3 receptors nrog siab affinity, activates downstream GPCR signaling pathways, tsub kom intracellular calcium concentration, thiab exerts muaj zog vasodilation, hypotension, excitation ntawm ntau cov nqaij mos cov nqaij mos, thiab txhawb lub glandular secretion. Nws excites central neurons thiab induces coj cwj pwm teb, ua ib tug classic peptide cuab tam rau tachykinin receptor functional identification, cardiovascular pharmacology thiab neuropeptide kev tshawb fawb. | Kev kho mob plawv, kev tshawb fawb ntawm cov leeg nqaij du, neuropeptide receptor pharmacology, glandular secretion mechanism, kev tshawb fawb mob thiab mob | Neurokinin 2 receptor (NK2R); Neurokinin 3 receptor (NK3R); GPCR signaling txoj kev |
Cim npe nrov: CAS: 69-25-0: eledoisin, Tuam Tshoj cas: 69-25-0: eledoisin manufacturers, lwm tus neeg, Hoobkas
