Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 33605-67-3 cargutocin hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 33605-67-3 cargutocin los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 33605-67-3: Cargutocin |
| Kev piav qhia | Cargutocin yog ib qho piv txwv ntawm oxytocin. Hydrocarbon saw hloov rau tus choj disulfide txhim kho metabolic stability. Nws activates oxytocin receptors los txhawb uterine smooth nqaij contraction, thiab yog siv nyob rau hauv kev ua hauj lwm induction, parturition, postpartum hemostasis thiab reproductive endocrine mechanism kev tshawb fawb. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Cov mis mos molecular | C₄₂H₆₅N₁₁O₁₂ |
| Molecular Luj (Da) | 916.05 |
Khoom Description
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Tag Nrho Amino Acid Sequence | Molecular Formula | Exact Mass (Da) | Nruab nrab MW (Da) | N-Terminal Hloov kho | C-Terminal Hloov kho | Qhov ntev (aa) |
| Cargutocin | Cargutocin; Y-5350; Statogin; CAS Nr .: 33605-67-3 | Oxytocin receptor agonist, Uterine contraction, Labor induction, Postpartum hemostasis, Disulfide hloov kev ruaj ntseg, Kev tshawb fawb txog kev xeeb tub | Tyrosine-isoleucine-glutamine-asparagine-aminobutyric acid-glycine-leucine-glycinamide (N-terminal butyrylation, backbone amide bond cyclization, tsis muaj disulfide) | C₄₂H₆₅N₁₁O₁₂ | 915.48 | 916.05 | N-terminal butyrylation, tsis muaj amine dawb | C-terminal amidation | 8 (core amino acids + davhlau ya nyob twg hloov kho) |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia Cov Cai | Luv -Lub Sijhawm Cia Cov Cai | Kua Stability | Khoom hmoov ruaj khov |
| PEB-CAR001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted; zam rov qab khov-thaw cycles | Khoom hmoov ruaj khov rau 6 lub hlis ntawm 2-8℃kaw thiab qhuav; npaj cov tshuaj aqueous tshiab ua ntej siv | ruaj khov rau 48 h ntawm 4 degree; ruaj khov rau 2 lub lis piam ntawm -20℃hauv aliquots. ** Cov dej zoo solubility, dawb do soluble hauv dej thiab dilute acetic acid **. Amide cyclized qauv tsis rhiab rau txo cov neeg ua haujlwm. Aqueous tov yooj yim degraded los ntawm peptidases nrog tsis zoo chav-kub stability | ruaj khov rau 3 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-CAR001 | Disulfide- hloov oxytocin analog nrog txhim kho metabolic stability thiab muaj zog uterotonic nyhuv | Cargutocin yog thawj - tiam carbon - hloov oxytocin analog. Nws hloov Cys1-Cys6 disulfide choj ntawm haiv neeg oxytocin nrog ib tug hydrophobic hydrocarbon saw thiab amide daim ntawv cog lus cyclization qauv, tshem tawm disulfide instability, ho txhim khu enzymatic tsis kam thiab nyob rau hauv vivo ib nrab-lub neej, thaum tuav siab affinity thiab agonistic kev ua si rau oxytocin receptor. Nws tshwj xeeb khi rau oxytocin receptors ntawm uterine du leeg hlwb, activates GPCR txoj hauv kev, tsub kom intracellular calcium concentration, thiab induces rhythmic uterine smooth nqaij contraction, muaj zog zog thiab ntev ntev tshaj li haiv neeg oxytocin. Cov molecule no ua haujlwm raws li cov cuab yeej classic peptide rau kev ua me nyuam endocrinology, parturition physiology thiab zog induction tshuaj txoj kev loj hlob, thiab kuj yuav siv tau nyob rau hauv pharmacological kev tshawb fawb ntawm postpartum hemostasis thiab uterine involution insufficiency. | Kev tshawb fawb txog kev xeeb tub endocrinology, Kev tshawb fawb txog kev yug me nyuam, kev ua haujlwm induction tshuaj, kev tshawb fawb tom qab yug me nyuam, Oxytocin pathway kawm, Gynecological pharmacology tshawb fawb | Oxytocin Receptor (OXTR); Uterine smooth nqaij contraction txoj kev; Calcium signaling txoj kev |
Cim npe nrov: CAS 33605-67-3 cargutocin, Tuam Tshoj CAS 33605-67-3 cargutocin manufacturers, lwm tus, Hoobkas
