Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 952720-86-4 marlumotide hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 952720-86-4 marlumotide los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| CAS | 935395-34-9 |
| Khoom npe | Vorumotide |
| Qeb | Kev tshawb fawb -qib Immunopeptide / Tumor Immunology Research Peptide |
| Purity (HPLC, %) | 95%/98%/99% |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure Description | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | N-Terminal Hloov kho | C-Terminal Hloov kho | Qhov ntev (aa) |
| Marlumotide | Marlumotide; WT1 (122-140); WT1-122A1 LONG; CAS Nr .: 952720-86-4 | WT1 antigen peptide, CTL epitope peptide, Kev txhaj tshuaj tiv thaiv kab mob, kev tsim tshuaj tiv thaiv qog nqaij hlav, kev tshawb fawb hematological oncology, qog tshuaj tiv thaiv kab mob | Serine-Glycine-Glutamine-Alanine-Tyrosine-Methionine-Phenylalanine-Proline-Asparagine -Alanine-Proline-Tyrosine-Leucine-Proline-Serine-Cysteine-Leucine-Glutamic acid{17}}Serine | C₉₃H₁₃₅N₂₁O₂₉S₂ | 2074.93 | 2075.32 | Dawb amine, unmodified | Dawb carboxyl, unmodified | 19 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia Cov Cai | Luv -Lub Sijhawm Cia Cov Cai | Kua Stability | Khoom hmoov ruaj khov |
| PEB-MAR001 | hmoov dawb | Khaws ntawm -20 degree, tiv thaiv lub teeb, kaw thiab qhuav, aliquoted; zam rov qab khov-thaw cycles thiab oxidation | Khoom hmoov ruaj khov rau 2 xyoos kaw thiab qhuav ntawm 2-8 degree; npaj aqueous daws freshly ua ntej siv, aliquots ruaj khov rau 1 lub hlis ntawm -20 degree | ruaj khov rau 72 h ntawm 4 degree; muaj cov dawb cysteine thiol pab pawg, nquag oxidation thiab dimerization. Tsis txhob raug cua ntev ntev thiab cov hlau ion paug | ruaj khov rau 3 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-MAR001 | HLA- txwv tsis pub CTL epitope peptide muab los ntawm WT1 protein, ua kom qog-T cell tiv thaiv tshwj xeeb, siv rau hauv cov tshuaj tiv thaiv qog thiab kev tshawb fawb txog kev tiv thaiv kab mob | Marlumotide yog HLA- txwv tsis pub cytotoxic T lymphocyte (CTL) epitope peptide sib haum rau cov amino acids 122 txog 140 ntawm Wilms qog 1 (WT1) protein, thiab yog ib qho tseem ceeb antigen tivthaiv ntawm WT1- cov tshuaj tiv thaiv qog nqaij hlav. Nws tuaj yeem tau txais thiab ua tiav los ntawm antigen- nthuav tawm cov hlwb (APCs), nthuav tawm ntawm lub xov tooj ntawm tes los ntawm MHC chav kawm kuv cov molecules, thiab tshwj xeeb ua rau WT1-targeted CD8⁺ cytotoxic T hlwb, inducing lawv lub hom phiaj tua ntawm WT1-zoo qog hlwb. WT1 tau qhia ntau yam hauv cov qog hematological xws li leukemia thiab ntau yam myeloma, nrog rau qee cov qog nqaij hlav, thiab ua lub hom phiaj tseem ceeb rau kev kho mob qog noj ntshav dav dav. Yog li ntawd, qhov no epitope peptide yog dav siv nyob rau hauv peptide qog tshuaj tiv thaiv kab mob, kev tshawb fawb qog immunotherapy, T cell activation mechanism kev tshawb fawb, thiab tus kheej qog cov tshuaj tiv thaiv kab mob. | Kev tshawb fawb qog noj tshuaj tiv thaiv kab mob qog noj ntshav, kev tsim tshuaj tiv thaiv qog, T cell activation mechanism kev tshawb fawb, WT1 tsom kev tshawb fawb, Hematological oncology immunology tshawb fawb, CTL epitope tshuaj ntsuam | WT1 antigen epitope (122{2}}140); MHC chav kawm I molecule kev nthuav qhia; CTL-mediated qog cell tua txoj kev |
Cim npe nrov: CAS 952720-86-4 marlumotide, Tuam Tshoj cas 952720-86-4 marlumotide manufacturers, lwm tus, Hoobkas
