Shanghai Sunite Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm tau peptide (306-317) cas 1003007-59-7 hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo tau peptide (306-317) cas 1003007-59-7 los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 1003007-59-7; Tau Peptide (306-317) |
| Ib ntus | |
| Peb tsab ntawv ib ntus | |
| Peptide purity (HPLC, %) | |
| Cov mis mos molecular | |
| Molecular Luj (Da) |
Product Basic Information Table
|
Khoom Lub Npe Lus Askiv |
Product Abbreviation / Alias |
Function Tags (comma-sib cais) |
Amino Acid Tag Nrho Lub Npe Sequence |
Molecular Formula |
Qhov hnyav Molecular (Da) |
Qhov Nruab Nrab Molecular Luj (Da) |
Terminal Hloov kho - N-terminus |
Terminal Hloov kho - C-terminus |
Qhov ntev (aa) |
|
Tau Peptide (306-317) |
#Tau(306-317) #Tau microtubule-binding repeat fragment; #PHF aggregation core peptide; #Tau phosphorylation pathology tshawb fawb |
Tau aggregation, paired helical filament (PHF) formation, microtubule assembly, kinase substrate, Alzheimer's disease, neurodegeneration |
Serine-Lysine-Valine-Serine-Serine-Proline-Serine-Serine-Serine-Serine-Proline-Serine |
C₅₄H₉₀N₂₀O₂₇ |
1414.635 |
1415.42 |
Tsis hloov |
Dawb carboxyl pawg |
12 |
Physicochemical Solubility & Cia Parameters
|
Khoom Code |
Qhov tshwm sim |
Pom zoo Dissolution Protocol (los ntawm hnyav) |
Solubility Reference |
Tsis pom zoo Solvents |
Ntev - Lub Sij Hawm Cia Cov Cai |
Luv -Lub Sijhawm Cia Cov Cai |
Kua Stability |
Khoom hmoov ruaj khov |
Muaj feem xyuam pH Range |
|
PEB-Tau02 |
Dawb lyophilized hmoov |
Dilute acetic acid, dej ultrapure; Tsawg solubility nyob rau hauv nruab nrab cov dej ntshiab, ntxiv glacial acetic acid los txhim kho solubility |
Ntau dua lossis sib npaug li 10mg / mL hauv 0.1% aqueous acetic acid |
Tsis muaj dej ntshiab, alkane organic solvents |
-20 degree, kaw kom deb ntawm lub teeb, aliquoted, tsis txhob rov khov-thaw |
2-8 degree, siv hauv 1 lub hlis; npaj tshiab ua ntej kev sim |
Ruaj khov rau 24 teev ntawm 4 degree |
3 xyoos ntawm -20 degree, 2 xyoos ntawm 4 degree |
3.0-7.0 |
Functional Description
|
Khoom Code |
Frontend Short Summary (rau cov npe tshawb nrhiav) |
Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg |
Cov cheeb tsam tshawb fawb (comma- cais) |
Hom phiaj / Receptor |
|
PEB-Tau02 |
Tau (306-317) yog cov tub ntxhais PHF6 aggregation fragment ntawm tib neeg Tau protein nrog ntau phosphorylatable serine residues, siv los tsim hauv vitro neurofibrillary tangle qauv |
Tau Peptide (306-317) yog PHF6 core sequence nyob rau hauv microtubule-binding domain of Tau protein, thaj tsam tseem ceeb mediating tau oligomerization, paired helical filaments (PHF) thiab neurofibrillary tangle los ua ke. Cov kab ke muaj ntau yam Ser-Pro kinase lees paub motifs, ua haujlwm raws li canonical substrate rau tau-kinases suav nrog GSK-3 thiab CDK5. Nyob rau hauv physiological tej yam kev mob, nws khi thiab stabilizes neuronal microtubules; hyperphosphorylation ua rau dissociation ntawm microtubules thiab spontaneous self-aggregation. Dav siv nyob rau hauv vitro assays rau tau aggregation inhibitor kev tshuaj ntsuam, kinase kev ntsuas ntsuas, pathological mechanism kawm ntawm Alzheimer's kab mob & frontotemporal dementia, neurotoxicity cell qauv, tsim nyog rau neuropathology thiab hloov kho protein ntau kev tshawb fawb pharmacology. |
Cov kab mob neurodegenerative, Alzheimer's kab mob, tau protein aggregation, paired helical filaments (PHF), kinase ntsuam xyuas, microtubule dynamics |
GSK-3, CDK5, Tubulin, Tau homo-oligomers |
Cov Ntaub Ntawv Tswj Xyuas Zoo
|
Khoom Code |
Purity Detection Method |
Molecular Weight Verification Method |
Kev Tswj Xyuas Qhov Ntsuas |
Impurity Control Standards |
|
PEB-Tau02 |
Rov qab-theem HPLC |
ESI-MS Mass Spectrometry |
Purity, dej ntsiab lus, acetate ntsev, hnyav hlau |
Ib qho impurity Tsawg dua lossis sib npaug li 2%, tag nrho impurities Tsawg dua lossis sib npaug li 5% |
SKU Specifications & Inventory Table
|
SKU Unique Code |
Yam khoom Code |
HPLC Purity |
Ntim Specification |
Lub Sijhawm Ua Haujlwm Ntau Lawm |
Customizable |
Optional Custom Modifications |
Cov ntaub ntawv suav nrog |
|
PEP-Tau02-98-1 |
PEB-Tau02 |
Ntau dua lossis sib npaug li 98% |
1mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Acetylation, amidation, fluorescent labeling, biotin labeling |
CoA, HPLC chromatogram, MS mass spectrum |
|
PEP-Tau02-98-5 |
PEB-Tau02 |
Ntau dua lossis sib npaug li 98% |
5mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Acetylation, amidation, fluorescent labeling, biotin labeling |
CoA, HPLC chromatogram, MS mass spectrum |
|
PEP-Tau02-95-1 |
PEB-Tau02 |
Ntau dua lossis sib npaug li 95% |
1mg ib |
3-7 hnub ua haujlwm |
Yog lawm |
Acetylation, amidation, fluorescent labeling, biotin labeling |
CoA, HPLC chromatogram, MS mass spectrum |
Cim npe nrov: Tau peptide (306-317) cas 1003007-59-7, Tuam Tshoj tau peptide (306-317) cas 1003007-59-7 manufacturers, lwm tus, Hoobkas
