Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 63631-40-3 bw-180c hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 63631-40-3 bw-180c los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 63631-40-3: BW-180C |
| Kev piav qhia | BW-180C yog ib qho muaj zog thiab xaiv kev sib tw antagonist ntawm bradykinin B2 receptor. Nws tshwj xeeb khi rau B2 receptors ntawm cov ntaub so ntswg ntawm tes thiab thaiv ntau yam kev cuam tshuam kev lom neeg los ntawm endogenous bradykinin, suav nrog vasodilation, nce capillary permeability, mob teeb liab transduction thiab inflammatory mediator tso tawm. Hloov kho nrog unnatural amino acids, nws nyob rau hauv vivo peptidase tsis kam yog ho txhim kho, nrog ntev lub sij hawm ntawm kev txiav txim tshaj li haiv neeg peptide antagonists, thiab tsis pom tseeb cross-activity ntawm B1 receptors. Nws yog dav siv nyob rau hauv bradykinin receptor subtype functional identification, mob conduction mechanism, inflammatory teb kev tswj, cardiovascular pharmacology thiab allergic kab mob, thiab yog ib tug classic cuab tam peptide rau bradykinin system kev tshawb fawb. |
| Peptide Purity (HPLC, %) | 95% / 98% / 99% |
| Dawb puag molecular mis | C₅₆H₇₅N₁₅O₁₁S |
| Dawb puag molecular hnyav (Da) | 1162.36, siab dua rau daim ntawv ntsev |
| Hom qauv | Hloov kho nonapeptide nrog ntau -site unnatural amino acid hloov pauv, dawb peptide / acetate ntsev |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| BW-180C | BW-180C bradykinin antagonist | Kev sib tw bradykinin B2 receptor antagonist, tiv thaiv -inflammatory & analgesic, vascular permeability tswj | Hloov kho nonapeptide; multi-site unnatural amino acid hloov pauv raws li haiv neeg bradykinin qaum (D-arginine, hydroxyproline, thienylalanine, thiab lwm yam), txhim kho receptor affinity thiab metabolic stability. | C₅₆H₇₅N₁₅O₁₁S | 1161.54 | 1162.36 | Dawb peptide / acetate | 9 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-BWC001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot kom tsis txhob rov qab khov-thaw mus. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; nkoj ntawm cov pob khov nab kuab pom zoo. | ruaj khov rau 7 hnub ntawm 4 degree. Solubility ntawm dej nruab nrab, pab los ntawm dilute acetic acid los yog acidic tsis; Dawb soluble hauv DMSO. Aqueous tov yog raug rau peptidase degradation; npaj tshiab ua ntej siv. | ruaj khov rau 3 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-BWC001 | Cov kev xaiv sib tw heev B2 receptor antagonist blocks bradykinin - kho mob inflammatory thiab vascular cuam tshuam | BW-180C yog ib qho muaj zog thiab xaiv kev sib tw antagonist ntawm bradykinin B2 receptor. Nws tshwj xeeb khi rau B2 receptors ntawm cov cell membranes thiab thim rov qab los ntawm ntau yam kab mob lom kho los ntawm endogenous bradykinin: vasodilation, nce capillary permeability, mob teeb liab transduction, inflammatory mediator tso tawm, du nqaij contraction, thiab lwm yam. Hloov kho nrog multi-site unnatural amino acids, nws nyob rau hauv vivo tseem ceeb ntawm peptidease kev ua hauj lwm ntev dua. antagonists, thiab tsis muaj kev cuam tshuam pom tseeb ntawm B1 receptors nrog kev xaiv zoo tshaj plaws. Nws yog dav siv nyob rau hauv bradykinin receptor subtype functional identification, mob conduction mechanism, inflammatory teb kev tswj, cardiovascular pharmacology thiab allergic kab mob, thiab yog ib tug classic cuab tam peptide rau bradykinin system kev tshawb fawb. | Kev tshawb fawb txog kev mob qog nqaij hlav, kev tshawb fawb txog kev mob inflammatory teb, bradykinin receptor subtype identification, cardiovascular pharmacology tshawb fawb, kev tshawb fawb kab mob | Bradykinin B2 receptor (BDKRB2); Inflammation thiab mob signaling txoj kev |
Cim npe nrov: CAS 63631-40-3 bw-180c, Tuam Tshoj cas 63631-40-3 bw-180c manufacturers, lwm tus, Hoobkas
