Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 148805-91-8 pendetide hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 148805-91-8 pendetide los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | Pendetide |
| Kev piav qhia | Pendetide (CAS: 148805-91-8), tseem hu ua GYK-DTPA, yog ib qho chelating peptide nyob rau hauv uas diethylenetriaminepentaacetic acid (DTPA) yog conjugated rau glycyl-tyrosine (GY) dipeptine side ntawm ib txoj hlua. DTPA yog polyaminopolycarboxylic acid chelator uas tsim cov complexes ruaj khov nrog ntau yam xim hlau radionuclides (piv txwv li, ¹¹¹In, ⁹⁰Y, ¹⁷⁷Lu). Hauv GYK (Gly-Tyr-Lys) tripeptide sequence, tyrosine residue enables radioiodination (¹²⁵I/¹³¹I), hos lysine side chain muab DTPA conjugation site. Raws li ib tug bifunctional chelator, Pendetide ua rau tib lub sij hawm radionuclide chelation thiab lub hom phiaj molecule conjugation, nrog rau dav siv nyob rau hauv radioimmunoimaging (RII), radioimmunotherapy (RIT), thiab lub hom phiaj xa tshuaj system tsim. |
| Peptide Purity (HPLC, %) | Ntau dua lossis sib npaug li 95% |
| Cov mis mos molecular | C₃₁H₄₇N₇O₁₄ |
| Molecular Luj (Da) | 741.74 ib |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Pendetide | Pendetide; conformationally constrained enkephalin derivative | Opioid receptor agonist peptide, analgesic & anti-inflammatory, neuromodulation, tawv nqaij soothing | Enkephalin derivative nrog D-amino acid hloov thiab disulfide daim ntawv cog lus conformational txwv; siab -kev xaiv δ-opioid receptor agonist nrog txhim kho kev ua kom muaj zog thiab ua kom muaj zog metabolic | C₂₇H₃₅N₅O₇S₂ | 593.2 | ~593.7 | Acetate | 5 (conformationally constrained pentapeptide) |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-PEN001 | Dawb hmoov | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau shipping ntawm ambient kub. | ruaj khov rau 7 hnub ntawm 4 degree. Acetate ntsev yog dawb do soluble hauv dej, dilute acetic acid thiab PBS. Conformationally constrained qauv resists enzymatic degradation nrog zoo stability ntawm physiological pH; disulfide daim ntawv cog lus nws yooj yim rau cleavage nyob rau hauv muaj zog alkaline tej yam kev mob. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-PEN001 | Pendetide, conformationally constrained siab -kev xaiv δ-opioid receptor agonist | Pendetide yog conformationally constrained enkephalin derivative. D-amino acid hloov pauv thiab disulfide cyclization xauv peptide hauv kev ua haujlwm zoo, txhim kho kev xaiv thiab kev sib raug zoo rau δ-opioid receptors. Receptor activation ua rau cov tshuaj analgesic thiab tiv thaiv - inflammatory teebmeem. Nws kuj ua rau ntawm daim tawv nqaij cov hlab ntsha xaus rau inhibit neurogenic o thiab nociceptive signaling, soothe tawv nqaij rhiab heev thiab stinging. Nws muaj qhov zoo dua metabolic stability thiab ntev ntev dua li cov neeg enkephalins. | Kev tshawb fawb Neuropharmacology, analgesic & anti- kev tshawb fawb inflammatory, kev txhim kho ntawm daim tawv nqaij, kev tshawb fawb opioid receptor, neurogenic o | δ-opioid receptor; neurogenic o txoj kev; nociceptive signaling |
Cim npe nrov: CAS 148805-91-8 Pendetide, Tuam Tshoj CAS 148805-91-8 Pendetide manufacturers, lwm tus neeg, Hoobkas
