Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm cas 774577-43-4 g4rgdsp (integrin-binding peptide) hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 774577-43-4 g4rgdsp (integrin-binding peptide) los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | G4RGDSP (integrin- khi peptide) |
| Kev piav qhia | G4RGDSP integrin-binding peptide (G4RGDSP, integrin-binding peptide), nrog rau qib GGGGRGDSP (9 amino acids), yog classic cell adhesion peptide. Nws N-terminus muaj plaub qhov sib law liag glycine residues (G4) raws li hloov tau yooj yim hydrophilic spacer caj npab, uas ua rau kom lub spatial accessibility thiab txav ntawm RGD functional motif thiab txo steric hindrance; Lub hauv paus ua haujlwm hauv cheeb tsam yog RGD (Arg-Gly-Asp) tripeptide motif, ib qho kev khaws cia integrin paub ib ntus nyob rau hauv cov protein matrix extracellular (xws li fibronectin, vitronectin, laminin, thiab lwm yam). RGD motif tshwj xeeb khi cov integrin receptor tsev neeg ntawm cov chaw ntawm tes (xws li v 3, v 5, 5 1, IIb 3, thiab lwm yam subtypes), kev sib kho ntawm tes -extracellular matrix adhesion, tsiv teb tsaws, kev loj hlob, thiab kev ciaj sia taus. Lub C-terminal Ser-Pro (SP) residues ntxiv ua raws li ib puag ncig ib puag ncig RGD hauv cov neeg fibronectin. Cov peptide no tau siv dav hauv cell culture nto functionalization (txhawb kev sib txuas ntawm tes), cov ntaub so ntswg engineering scaffold hloov kho, 3D bioprinting chondrocyte tus me nyuam nqa, microfluidic nti cell capture, tsom xa tshuaj, thiab integrin signaling txoj kev tshawb fawb. |
| Peptide Purity (HPLC, %) | Ntau dua lossis sib npaug li 98% |
| Cov mis mos molecular | C₂₈H₄₆N₁₂O₁₃ |
| Molecular Luj (Da) | 758.74 |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| G4RGDSP (integrin- khi peptide) | G4RGDSP integrin- khi peptide; RGD cell adhesion peptide; qog aiming peptide | Integrin-Tim phiaj peptide, kev tswj hwm ntawm tes, kev tiv thaiv qog nqaij hlav, angiogenesis inhibition, hloov kho cov ntaub so ntswg engineering | Linear peptide muaj RGD core motif nrog G4 glycine spacer rau kev txhim kho yooj yim thiab nkag tau yooj yim; tshwj xeeb khi integrins v ₃ thiab 5 ₁ los kho cell adhesion thiab inhibit qog angiogenesis thiab ntxeem tau | C₂₄H₄₁N₉O₁₂ | 631.29 | ~631.6 | Acetate | 8 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-RGD004 | Dawb hmoov | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau shipping ntawm ambient kub. | ruaj khov rau 7 hnub ntawm 4 degree. Acetate ntsev yog dawb do soluble hauv dej, dilute acetic acid thiab PBS. Zoo stability nyob rau hauv acidic rau nruab nrab tej yam kev mob; aspartic acid side chain nquag degradation nyob rau hauv muaj zog alkaline tej yam kev mob. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-RGD004 | G4RGDSP integrin- khi peptide lub hom phiaj integrins los tswj cell adhesion & angiogenesis | G4RGDSP yog ib qho kev sib koom ua ke - phiaj peptide uas muaj RGD core motif, nrog rau tetraglycine spacer los txhim kho spatial accessibility thiab khi yooj. Nws tshwj xeeb khi integrin receptors v ₃ thiab 5 ₁ ntawm lub xovtooj ntawm tes los kho cov xovtooj ntawm -ECM adhesion, thiab kev sib tw inhibits integrin signaling thaum qog angiogenesis los suppress qog cell invasion thiab metastasis. Nws kuj yog siv rau kev hloov kho ntawm cov ntaub so ntswg engineering scaffolds los txhawb cov cell adhesion thiab kev loj hlob. | Kev tshawb fawb ntawm cell adhesion, qog metastasis & angiogenesis, cov ntaub so ntswg engineering & biomaterials, tsom kev txhim kho tshuaj, integrin biology | Integrins v ₃ / 5 ₁; cell-matrix adhesion txoj kev; angiogenic signaling txoj kev |
Cim npe nrov: cas 774577-43-4 g4rgdsp (integrin-binding peptide), Tuam Tshoj cas 774577-43-4 g4rgdsp (integrin-binding peptide) manufacturers, lwm tus neeg, Hoobkas
