Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov tuam txhab ua lag luam thiab cov chaw muag khoom ntawm h-glu-pro-leu-gln-leu-lys-met-oh hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo h-glu-pro-leu-gln-leu-lys-met-oh los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Kev piav qhia | H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH (EPLQLKM, CAS: 683750-83-6) is a 7amino aid the line{12} sequence Glu-Pro-Leu-Gln-Leu-Lys-Met (EPLQLKM), featuring ib pawg amino pub dawb ntawm N-terminus thiab pawg carboxyl dawb ntawm C- Cov peptide muaj ib tug glutamic acid (Glu, acidic), ib tug proline (Pro, conformational tig), ob leucines (Leu, hydrophobic), ib tug glutamine (Gln, polar), ib tug lysine (Lys, yooj yim), thiab ib tug methionine (Met, hydrophobic sulfur-muaj), nrog rau tag nrho cov isoelectric physics, kwv yees li 9 p. tej yam kev mob. Lub proline residue ntawm txoj hauj lwm 2 qhia txog kev hloov pauv ntawm peptide qaum qaum, cuam tshuam rau tag nrho peb-dimensional conformation. Ob lub leucines thiab ib qho methionine muab hydrophobicity, muaj peev xwm koom nrog kev sib cuam tshuam nrog cov protein hydrophobic hnab los yog lipid membranes. Cov peptide no tuaj yeem ua haujlwm raws li cov cuab yeej peptide rau cov kev tshawb fawb ntawm cov protein-protein kev sib cuam tshuam, tus qauv peptide rau kev tshawb fawb txog enzyme substrate, los yog ua lub tsev thaiv rau ntev peptide sequences. Cov methionine residue yuav tsum tau saib xyuas kom tsis txhob oxidation (methionine sulfoxidation) thaum khaws cia thiab siv; cia nyob rau hauv inert gas tiv thaiv yog pom zoo. |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| H-Glu-Pro-Leu-Gln-Leu-Lys-Met-OH | EPLQLKM heptapeptide; MMP substrate heptapeptide | Protease substrate peptide, metalloproteinase substrate, enzyme kev soj ntsuam peptide, enzyme inhibitor kev tshuaj ntsuam | Linear heptapeptide Glu-Pro-Leu-Gln-Leu-Lys-Met nrog dawb C-terminal carboxylic acid; muaj proline tig, hydrophobic leucine, zoo them lysine thiab methionine, ua ib tug tshwj xeeb cleavage substrate rau matrix metalloproteinases (MMPs) | C₃₈H₆₇N₉O₁₁S | 857.47 | ~857.9 | Dawb peptide | 7 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-EPL07 | Dawb hmoov | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb, nyob rau hauv inert gas. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; tiv thaiv cov pa oxygen thaum thauj khoom. | ruaj khov rau 7 hnub ntawm 4 degree. Soluble nyob rau hauv dilute acetic acid, PBS thiab DMSO. Methionine residue yog rhiab heev rau oxygen thiab nquag oxidative inactivation. Tsis txhob cuam tshuam rau huab cua thiab oxidants ntev. Peptide bonds nquag hydrolysis nyob rau hauv muaj zog alkaline tej yam kev mob. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav, tiv thaiv los ntawm lub teeb thiab nyob rau hauv inert roj. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-EPL07 | EPLQLKM heptapeptide ua ib qho substrate rau MMP metalloproteinases | EPLQLKM yog ib qho tshwj xeeb substrate peptide rau matrix metalloproteinases (MMP-2/MMP-9), muaj cov tub ntxhais MMP paub thiab qhov chaw cleavage. Nws yog tshwj xeeb cleaved los ntawm activated MMPs los tsim kom pom cov khoom tawg, thiab yog siv rau kom muaj nuj nqis MMP kev soj ntsuam, enzyme kinetics kev tshawb fawb, MMP inhibitor kev tshuaj ntsuam thiab kev soj ntsuam kev ua tau zoo. | Enzymology & inhibitor kev tshuaj ntsuam, kev tshawb nrhiav qog nqaij hlav, kev tshawb nrhiav cov ntaub so ntswg, kev ntsuam xyuas kev ua haujlwm protease, tshuaj nrhiav pom | Matrix metalloproteinases MMP-2 / MMP-9; protease active site; enzymatic peptide daim ntawv cog lus cleavage site |
Cim npe nrov: h-glu-pro-leu-gln-leu-lys-met-oh, China h-glu-pro-leu-gln-1}{5}{1} manufacturers, lwm tus neeg, Hoobkas
