Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas: 1447799-33-8 reltecimod tfa hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas: 1447799-33-8 reltecimod tfa los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 1447799-33-8 Reltecimod TFA Nr |
| Kev piav qhia | Reltecimod yog ib qho hluavtaws peptide tsom rau CD28 costimulatory txoj hauv kev. Nws xaiv khi rau CD28 dimer interface thiab attenuates CD28 / B7-2 teeb liab hloov, nruab nrab inhibits cov lus teb ntau dhau yam tsis muaj kev thaiv lub cev tsis muaj zog. Nws txo cov ntaub so ntswg thiab lub cev puas tsuaj hauv sepsis thiab necrotizing cov ntaub so ntswg mos, thiab tiv thaiv kab mob kab mob, endotoxins thiab ionizing hluav taws xob. Nws yog ib qho tseem ceeb cov cuab yeej peptide rau inflammatory immunomodulation, kis raug mob thiab radioprotection tshawb fawb. |
| Peptide Purity (HPLC, %) | 95% / 98% / 99% |
| Dawb puag molecular mis | C₄₆H₇₂N₁₀O₁₅S |
| Dawb puag molecular hnyav (Da) | 1037.19, siab dua rau TFA ntsev daim ntawv |
| Hom qauv | Linear decapeptide, trifluoroacetate ntsev |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Reltecimod TFA | Reltecimod trifluoroacetate; AB-103 TFA | CD28 costimulatory pathway modulator, tiv thaiv- mob, tiv thaiv- kis mob, xov tooj cua tiv thaiv | Linear decapeptide caj qaum, tsom rau CD28 dimer interface, xaiv attenuating costimulatory signals | C₄₆H₇₂N₁₀O₁₅S·xC₂HF₃O₂ | 1036.49 (dawb puag) | 1037.19 (dawb puag) | Trifluoroacetate hmoov | 10 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-REL001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav, tiv thaiv los ntawm lub teeb, hauv qab cua nitrogen. Khaws kom deb ntawm cov dej noo. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau luv luv - lub sij hawm shipping ntawm ambient kub. | Nyob ruaj khov rau 14 hnub ntawm 4 degree. Solubility: ~ 80-100 mg / mL hauv DMSO (yuav tsum tau sonication); <0.1 mg/mL hauv dej. Npaj aqueous ua hauj lwm tov los ntawm serial dilution los ntawm DMSO Tshuag. | ruaj khov rau 3 xyoos ntawm -20℃thiab 2 xyoos ntawm 4 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-REL001 | Selective CD28 modulator, me ntsis suppresses hyperinflamation, attenuates kis kab mob thiab hluav taws xob raug mob | Reltecimod yog ib qho hluavtaws peptide tsom rau CD28 dimer interface ntawm T hlwb. Nws xaiv kom txo qis CD28 / B7-2 costimulatory signals kom tswj tau cov lus teb hyperinflammatory yam tsis muaj kev thaiv lub cev tsis muaj zog. Nws txo cov ntaub so ntswg thiab lub cev puas tsuaj hauv sepsis thiab necrotizing cov ntaub so ntswg mos, tiv thaiv kab mob kab mob, endotoxins thiab ionizing hluav taws xob, thiab txo cov neeg tuag hauv cov qauv kab mob. | Kev tshawb fawb sepsis / septic shock, necrotizing mos mos kab mob, inflammatory immunomodulation, hluav taws xob raug mob tiv thaiv | T-cell nto antigen CD28; CD28/B7 costimulatory txoj kev |
Cim npe nrov: CAS: 1447799-33-8 reltecimod tfa, Tuam Tshoj cas: 1447799-33-8 reltecimod tfa manufacturers, lwm tus neeg, Hoobkas
