Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas: 179822-83-4: diapep277 hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas: 179822-83-4: diapep277 los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 179822-83-4: DiaPep 277 |
| Kev piav qhia | DiaPep277 yog ib qho 24-amino-acid immunomodulatory peptide tau los ntawm cov protein ua kom poob siab 60 (HSP60). Nws modulates diabetogenic T-cov haujlwm ntawm tes, txhawb kev tiv thaiv lub cev tiv thaiv kab mob, inhibits autoreactive T-cell nres ntawm pancreatic -cells, thiab ncua kev pib thiab kev loj hlob ntawm hom 1 mob ntshav qab zib. Nws sib npaug pro- mob thiab tiv thaiv - mob cytokines thiab ua rau muaj kev tiv thaiv splenic T-cell teb, ua haujlwm tseem ceeb peptide rau kev tshawb nrhiav kab mob autoimmune mechanism, kev tiv thaiv kev tiv thaiv kab mob thiab kev txhim kho peptide immunotherapy. |
| Peptide Purity (HPLC, %) | 95% / 98% / 99% |
| Dawb peptide molecular mis | C₁₀₆H₁₈₀N₂₈O₃₄ |
| Dawb peptide molecular hnyav (Da) | 2390.73, siab dua rau daim ntawv ntsev |
| Hom qauv | Linear 24-mer peptide, dawb peptide / acetate |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Peb 277 | Immunomodulatory peptide DiaPep277; HSP60 437-460 peptide | Immunomodulation, pancreatic -kev tiv thaiv ntawm tes, kev cuam tshuam ntshav qab zib hom 1, kev tiv thaiv kab mob tiv thaiv kab mob | Linear 24-mer peptide muab tau los ntawm residues 437-460 ntawm tshav kub shock protein HSP60, natural homologous sequence backbone | C₁₀₆H₁₈₀N₂₈O₃₄ | 2389.32 | 2390.73 | Dawb peptide / acetate | 24 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-DIA001 | hmoov dawb | Khaws ntawm -20℃, kaw, qhuav thiab tiv thaiv los ntawm lub teeb . -80℃aliquot cia pom zoo rau kev khaws cia ntev. | ruaj khov rau 2 lub lis piam ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau luv luv - lub sij hawm shipping ntawm ambient kub. | Ruaj khov rau 7 hnub ntawm 4℃hauv cov kua dej. Dawb soluble hauv dej, dilute acetic acid, DMSO thiab DMF. Rov qab khov-thaw ua kom peptide degradation. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-DIA001 | HSP60-derived immunomodulatory peptide, induces lub cev tiv thaiv kab mob, ncua kev mob ntshav qab zib hom 1 | DiaPep277 yog muab los ntawm residues 437-460 ntawm tshav kub shock protein HSP60. Nws modulates diabetogenic T-cov haujlwm ntawm tes, txhawb kev tiv thaiv lub cev tiv thaiv kab mob, inhibits autoreactive T{{5} cell nres ntawm pancreatic -cells, thiab ncua kev pib thiab kev loj hlob ntawm hom 1 mob ntshav qab zib. Nws sib npaug pro- mob thiab tiv thaiv - mob cytokines thiab ua rau muaj kev tiv thaiv splenic T{{11}cov lus teb ntawm tes, ua haujlwm tseem ceeb peptide rau cov kab mob autoimmune thiab kev tshawb fawb txog kev tiv thaiv kab mob. | Hom 1 mob ntshav qab zib mellitus mechanism, kev tshawb fawb kab mob autoimmune, kev tiv thaiv kev tiv thaiv kab mob, kev txhim kho peptide immunotherapy | Heat shock protein 60 (HSP60) ntsig txog txoj kev; T-txoj kev costimulatory cell |
Cim npe nrov: cas:179822-83-4: diapep277, Suav teb cas:179822-83-4: diapep277 manufacturers, lwm tus neeg, Hoobkas
