Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 124904-93-4 ganirelix hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau kev lag luam wholesale bulk zoo cas 124904-93-4 ganirelix los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe CAS | 124904-93-4: Ganirelix |
| Kev piav qhia | Ganirelix yog thib peb - tiam neeg xaiv GnRH receptor kev sib tw antagonist. Nws sai thiab thim rov qab khi rau GnRH receptors nyob rau hauv lub anterior pituitary, blocks endogenous GnRH teeb liab transduction, thiab koob tshuaj -nyob ntawm inhibits lub secretion ntawm luteinizing hormone (LH) thiab follicle-stimulating hormone (FSH), yog li sai sai suppressing gonadal hormone synthesis. Nrog rau qhov pib sai thiab tsis muaj qhov tshwm sim thawj zaug- nce cov txiaj ntsig, nws tau siv dav rau kev tshawb fawb txog kev tshawb fawb thiab tshuaj peptide hauv thaj chaw xws li tswj zes qe menyuam hyperstimulation hauv kev pab yug me nyuam, endometriosis, thiab kev sib deev hormone- nyob ntawm cov qog. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Dawb peptide molecular mis | C₈₀H₁₁₃ClN₁₈O₁₃ |
| Dawb peptide molecular hnyav (Da) | 1570.33, me ntsis siab dua rau acetate ntsev |
| Hom qauv | D-amino acid hloov kho decapeptide nrog ob lub davhlau ya nyob twg thaiv |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | N-Terminal Hloov kho | C-Terminal Hloov kho | Ntev (aa) |
| Ganirelix | Ganirelix acetate; GnRH antagonist | GnRH receptor antagonism, Gonadotropin inhibition, Pab kev tshawb fawb txog kev tsim tawm, Tsis muaj hluav taws xob - nce nyhuv, Thib peb - tiam antagonist, kev tswj hwm kev sib deev | Decapeptide txha caj qaum nrog ntau D-arromatic amino acids, davhlau ya nyob twg thaiv | Dawb peptide C₈₀H₁₁₃ClN₁₈O₁₃ | 1569.83 | 1570.33 | Acetylation, tsis muaj amine dawb | Amidation | 10 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia Cov Cai | Luv -Lub Sijhawm Cia Cov Cai | Kua Stability | Khoom hmoov ruaj khov |
| PEB-GAN001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted; zam rov qab khov-thaw cycles | ruaj khov rau 1 lub hlis ntawm 2-8℃kaw & qhuav; tolerable rau lub sij hawm luv luv chav tsev kub shipping | ruaj khov rau 7 hnub ntawm 4 degree; ruaj khov rau 3 lub hlis ntawm -20℃hauv aliquots. ** Cov dej zoo solubility, dawb do soluble hauv dej thiab physiological tsis **. D-amino acids thiab kev hloov kho davhlau ya nyob twg ua rau muaj kev tiv thaiv enzyme | ruaj khov rau 3 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-GAN001 | Thib peb- tiam sis sib tw GnRH receptor antagonist uas sai thiab thim rov qab inhibits gonadotropins uas tsis muaj qhov pib tshwm sim -nce | Ganirelix mimics endogenous GnRH ntawm spatial conformation, khi nrog siab affinity rau ligand -binding hnab tshos ntawm pituitary GnRH receptors, kev sib tw thaiv kev khi ntawm endogenous GnRH rau receptors, inhibits downstream cAMP/PKA signaling pathway ntawm LH, thiab sai sai txo. Tsis zoo li GnRH agonists, nws tsis muaj qhov pib receptor agonist flare- nce theem, ncaj qha thiab nrawm nrawm nrawm rau lub gonadal axis tom qab kev tswj hwm, thiab pituitary muaj nuj nqi rov qab sai sai tom qab txiav tawm. Los ntawm inhibiting gonadotropin secretion, nws ntxiv txo qis peripheral txiv neej cov tshuaj hormones xws li estradiol thiab testosterone, thiab tswj kev sib deev thiab kev ua haujlwm gonadal. | Kev tshawb fawb thev naus laus zis, kev tshawb fawb endometriosis, Kev sib deev hormone tswj, Pituitary -gonadal axis kawm, GnRH txoj kev tsom xam, Peptide tshuaj txhim kho | Gonadotropin-Tshuaj Hormone Receptor (GnRHR); Gonadotropin secretion inhibitory txoj hauv kev; Pituitary-gonadal axis tswj txoj hauv kev |
Cim npe nrov: CAS 124904-93-4 ganirelix, Tuam Tshoj cas 124904-93-4 ganirelix manufacturers, lwm tus, Hoobkas
