Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 1606994-55-1 elamipretide tfa hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 1606994-55-1 elamipretide tfa los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 1606994-55-1:Elamipretide TFA |
| Kev piav qhia | Elamipretide (tseem hu ua SS-31, MTP-131) yog ib tiam tshiab mitochondria-targeted antioxidant tetrapeptide. Nws tshwj xeeb khi rau cardiolipin ntawm lub mitochondrial puab daim nyias nyias thiab enriches nyob rau hauv mitochondria, precisely scavenges mitochondrial reactive oxygen hom, inhibits mitochondrial permeability hloov pore qhib, txhim kho mitochondrial respiratory saw muaj nuj nqi thiab ATP ntau lawm, thiab txo apoptosis nyob rau hauv oxidation. Nws ua rau muaj kev tiv thaiv tseem ceeb ntawm myocardial ischemia-reperfusion raug mob, neurodegeneration, mob raum thiab kev laus-txog mitochondrial tsis ua haujlwm. Cov ntsev trifluoroacetate yog HPLC purification nruab nrab nrog cov dej solubility zoo. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Dawb peptide molecular mis | C₃₃H₄₉N₉O₅ |
| Dawb peptide molecular hnyav (Da) | 651.80, siab dua rau TFA ntsev daim ntawv |
| Hom qauv | Hloov kho tetrapeptide, tsim nrog unnatural amino acids, C-terminal amidated, trifluoroacetate ntsev |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Puv Amino Acid Sequence | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Hloov kho hom | Daim ntawv ntsev |
| Elamipretide TFA | Elamipretide TFA; SS-31; MTP-131 | Mitochondrial targeting, Antioxidant, Mitochondrial tiv thaiv, Ischemia-reperfusion raug mob, Anti- laus, Neuroprotection | D-Arg-2',6'-dimethyl-L-Tyr-L-Lys-L-Phe-NH₂ | Dawb peptide C₃₃H₄₉N₉O₅ | 651.39 | 651.8 | D-amino acid + unnatural amino acid + C-terminal amidation | Trifluoroacetate hmoov |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia Cov Cai | Luv -Lub Sijhawm Cia Cov Cai | Kua Stability | Khoom hmoov ruaj khov |
| PEB-ELA001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted; zam rov qab khov-thaw mus thiab muaj zog oxidizing ib puag ncig | ruaj khov rau 1 lub hlis ntawm 2-8℃kaw & qhuav; ice pob shipping pom zoo | ruaj khov rau 7 hnub ntawm 4 degree; ruaj khov rau 2 lub hlis ntawm -20℃hauv aliquots. ** Dej solubility zoo heev, dawb soluble hauv dej thiab physiological tsis **. D-amino acids thiab cov kev hloov kho lub davhlau ya nyob twg ua rau muaj kev tiv thaiv enzymatic; dimethyltyrosine site yuav tsum tsis txhob muaj zog oxidants | ruaj khov rau 3 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-ELA001 | Mitochondria- tsom rau tetrapeptide uas ua kom muaj txiaj ntsig zoo hauv mitochondria, scavenges ROS thiab txhim kho txoj kev ua pa los tiv thaiv cov hlwb | Elamipretide tshwj xeeb lees paub thiab khi rau cardiolipin molecules ntawm mitochondrial inner membrane ntawm nws cov qauv cationic thiab hydrophobic amphipathic, thiab ua kom muaj txiaj ntsig zoo ntawm sab mitochondrial matrix, nrog lub hom phiaj siab ntau dua li qib cytosolic. Nws ncaj qha scavenges reactive oxygen hom xws li superoxide anions thiab hydroxyl radicals tsim los ntawm mitochondria los ntawm dimethyltyrosine residue, thaum inhibiting qhov qhib ntawm mitochondrial permeability hloov pore (mPTP), tswj mitochondrial membrane thiab structural integrity, txhim kho txoj kev ua pa ntawm cov ntaub so ntswg ua haujlwm, thiab txo cov kev ua haujlwm ntawm cov kab mob. oxidative kev nyuaj siab. Nws qhia txog kev tiv thaiv lub cev tseem ceeb hauv cov qauv ntawm myocardial ischemia-reperfusion, cerebral ischemia, mob raum raug mob thiab cov kab mob neurodegenerative, thiab yog cov cuab yeej tseem ceeb peptide rau kev kawm txog mitochondrial dysfunction-txog kab mob. | Mitochondrial function study, Ischemia-reperfusion raug mob, Neurodegenerative kab mob, tiv thaiv Myocardial, raum raug mob, Anti- tshawb fawb kev laus | Mitochondrial inner membrane cardiolipin; Mitochondrial permeability hloov pore; Mitochondrial oxidative kev nyuaj siab thiab ua pa ua haujlwm tswj txoj hauv kev |
Cim npe nrov: CAS 1606994-55-1 elamipretide tfa, Tuam Tshoj cas 1606994-55-1 elamipretide tfa manufacturers, lwm tus, Hoobkas
