Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 204248-78-2 omiganan hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 204248-78-2 omiganan los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS 204248-78-2 Omiganan Nr |
| Kev piav qhia | Omiganan yog ib qho tshiab -generation synthetic cationic antimicrobial peptide. Nws cov khoom zoo amino acid residues khi rau qhov tsis zoo them nyiaj phospholipids thiab lipopolysaccharides ntawm microbial nto, thiab hydrophobic sab chains ntxig rau hauv cov cell membrane los ua transmembrane pores, cuam tshuam membrane barrier muaj nuj nqi thiab transmembrane muaj peev xwm tua cov kab mob sai. Nws daim nyias nyias - lub hom phiaj lub cev lub cev tsis tshua muaj peev xwm ua rau cov kab mob tsis zoo. Cov khoom no nthuav tawm kev ua haujlwm zoo tshaj plaws tiv thaiv Gram- cov kab mob zoo, Gram- cov kab mob tsis zoo, cov kab mob fungi thiab qee cov kab mob hauv lub hnab, suav nrog ntau hom - tshuaj tiv thaiv kab mob xws li methicillin-resistant * Staphylococcus aureus* (MRSA) thiab vancomycin * -}. Nws kuj inhibits lub zos pro-inflammatory cytokine tso tawm thiab alleviates inflammatory teb. Nws yog siv tshwj xeeb hauv kev tshawb fawb txog tshuaj tiv thaiv kab mob - kis mob xws li kab mob ntawm daim tawv nqaij thiab mucosal kab mob thiab catheter- kab mob ntsig txog, thiab yog cov cuab yeej tseem ceeb peptide rau kev tshuaj xyuas cov tshuaj tiv thaiv kab mob peptides thiab txhim kho cov tshuaj tiv thaiv - tshuaj - cov tshuaj tiv thaiv kab mob. |
| Peptide Purity (HPLC, %) | 95% / 98% / 99% |
| Dawb puag molecular mis | C₇₇H₁₁₅N₂₅O₁₃ |
| Dawb puag molecular hnyav (Da) | 1610.9, siab dua rau hydrochloride / acetate daim ntawv |
| Hom qauv | Linear cationic antimicrobial peptide, dawb daim ntawv / hydrochloride |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Omiganan | Omiganan; IB-226 | Dav -spectrum cationic antimicrobial peptide, tiv thaiv-MDR kab mob, tshuaj pleev ib ce los tiv thaiv- kis kab mob, tiv thaiv- mob | Synthetic linear cationic antimicrobial peptide nplua nuj nyob rau hauv arginine thiab tryptophan residues; amphiphilic qauv exerts bactericidal kev ua si ntawm lub cev daim nyias nyias cuam tshuam | C₇₇H₁₁₅N₂₅O₁₃ | 1609.9 | 1610.9 | Dawb daim ntawv / Hydrochloride | 12 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-OMI001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau luv - lub sij hawm shipping ntawm ambient kub. | Nyob ruaj khov rau 14 hnub ntawm 4 degree. Dawb soluble nyob rau hauv acidic aqueous tov thiab dilute acetic acid; zoo solubility nyob rau hauv nruab nrab physiological tsis. Cationic peptide; zam kev sib xyaw nrog cov khoom muaj zog anionic. | ruaj khov rau 3 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-OMI001 | Dav -spectrum cationic antimicrobial peptide nrog cov kab mob sai sai, tsis muaj zog thiab tshuaj pleev ib ce los tiv thaiv- kev ua haujlwm inflammatory | Omiganan yog ib qho tshiab -generation synthetic cationic antimicrobial peptide. Nws cov txiaj ntsig zoo arginine residues khi rau qhov tsis zoo them phospholipids thiab lipopolysaccharides ntawm cov kab mob microbial, thiab tryptophan hydrophobic sab chains ntxig rau hauv cov cell membrane los tsim cov txheej txheem transmembrane pores, cuam tshuam cov membrane kev ncaj ncees thiab transmembrane muaj peev xwm tua cov kab mob sai. Lub cev daim nyias nyias no -lytic mechanism tsis tshua muaj peev xwm ua rau cov kab mob tsis zoo. Cov khoom no nthuav tawm cov haujlwm zoo tshaj plaws tiv thaiv Gram- cov kab mob zoo, Gram- cov kab mob tsis zoo, cov kab mob fungi thiab qee cov kab mob hauv lub hnab, suav nrog ntau hom - tshuaj tiv thaiv kab mob xws li MRSA thiab VRE. Nws kuj inhibits lub zos pro-inflammatory cytokine tso tawm thiab alleviates inflammatory teb. Nws yog siv tshwj xeeb hauv kev tshawb fawb txog tshuaj tiv thaiv kab mob - kis mob xws li kab mob ntawm daim tawv nqaij thiab mucosal kab mob thiab catheter- kis kab mob, thiab yog cov cuab yeej tseem ceeb peptide rau kev tsom xam cov tshuaj tiv thaiv kab mob peptides thiab txhim kho cov tshuaj tiv thaiv - tshuaj- cov tshuaj tiv thaiv kab mob. | Antibacterial peptide mechanism kev tshawb fawb, MDR kab mob kev tshawb fawb, tshuaj tiv thaiv kab mob -kev txhim kho tshuaj, tawv nqaij & mucosal kab mob kev tshawb fawb, kev kawm tiv thaiv kab mob | Microbial cell membrane cuam tshuam lub cev; Local inflammatory regulatory txoj kev |
Cim npe nrov: CAS 204248-78-2 omiganan, Tuam Tshoj cas 204248-78-2 omiganan manufacturers, lwm tus, Hoobkas
