CAS 2130912-34-2 Selcopintide CAS 2130912-34-2

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CAS 2130912-34-2 Selcopintide CAS 2130912-34-2
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CAS: 2130912-34-2 Nr
Cov qauv tseem ceeb: Synthetic P-selectin targeting peptide uas ua raws li lub ntsiab lus tseem ceeb ntawm selectin ligand, tshwj xeeb thaiv P-selectin- mediated cell adhesion thiab alleviates inflammatory cascade thiab thrombosis
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Cov ntaub ntawv ntsig txog
COA/MS/HPLC Report
Peptide Dissolution thiab Cia Phau Ntawv Qhia
Qeb
Anti-inflammatory & Antithrombotic Peptide / Selectin Adhesion Inhibitor
Kev faib tawm yam khoom
Pharmaceutical Peptides
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Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 2130912-34-2 selcopintide hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 2130912-34-2 selcopintide los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.

 

Khoom npe CAS: 2130912-34-2: Secopintide
Kev piav qhia Selcopintide yog P-selectin tsom los tiv thaiv adhesion peptide. Los ntawm kev sib tw thaiv kev cuam tshuam ntawm P-selectin thiab leukocyte PSGL-1, nws inhibits qhov txawv txav thiab kev sib sau ntawm neutrophils thiab platelets ntawm vascular endothelium, txo cov kab mob ntawm tes infiltration thiab microthrombosis, yog li txo cov ntaub so ntswg puas tsuaj los ntawm ischemia-reperfusion thiab inflammatory ntau dhau. Nws tsis cuam tshuam rau ib txwm coagulation muaj nuj nqi nrog tsawg los ntshav txaus. Siv rau hauv kev tshawb fawb mechanism thiab tshiab anti-inflammatory antithrombotic peptide txoj kev loj hlob rau mob ischemic raug mob, thromboinflammation, organ ischemia-reperfusion thiab lwm yam teb.
Peptide purity (HPLC, %) 95%/98%/99%
Theoretical molecular hnyav (Da) ~ 1100 (raws li qhov tseeb hluavtaws batch)
Hom qauv Site-modified linear luv peptide, selectin ligand mimetic

 

Product Basic Information Table

 

Khoom Lub Npe Lus Askiv Product Abbreviation / Alias Function Tags (comma-sib cais) Core Structure Molecular Formula Exact Mass (Da) Qhov nruab nrab MW (Da) Hloov kho hom Ntev (aa)
Selcopintide Selcopintide; P-selectin inhibitory peptide Selectin adhesion blockade, Tiv thaiv -inflammatory & antithrombotic, Ischemia- tiv thaiv reperfusion, Neutrophil activation inhibition, Thromboinflammation, Targeted peptide Linear luv peptide qaum nrog optimized selectin khi qhov chaw mimic Loj luv peptide, raug rau batch MS - ~ 1100 (theoretical) Site- hloov ligand mimetic qauv ~8

 

Physicochemical Solubility & Cia Parameters

 

Khoom Code Qhov tshwm sim Ntev - Lub Sij Hawm Cia Cov Cai Luv -Lub Sijhawm Cia Cov Cai Kua Stability Khoom hmoov ruaj khov
PEB-SEL002 hmoov dawb Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted; zam rov qab khov-thaw cycles ruaj khov rau 2 lub lis piam ntawm 2-8℃kaw & qhuav; ice pob shipping pom zoo ruaj khov rau 48h ntawm 4 degree; ruaj khov rau 2 lub lis piam ntawm -20℃hauv aliquots. ** Dej solubility zoo heev, dawb soluble hauv dej thiab physiological tsis **. luv peptide yooj yim degraded los ntawm peptidases nrog kev ua kom sai sai ntawm chav tsev kub ruaj khov rau 2 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj

 

Functional Description

 

Khoom Code Frontend Short Summary (rau cov npe tshawb nrhiav) Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg Cov cheeb tsam tshawb fawb (comma- cais) Lub Hom Phiaj / Txoj Kev
PEB-SEL002 P-selectin targeted blocking peptide uas inhibits leukocyte-platelet adhesion thiab alleviates ischemia-reperfusion raug mob thiab thromboinflammation Selcopintide ua raws li qhov tseem ceeb ntawm kev sib koom ua ke ntawm haiv neeg P-selectin ligand, sib tw khi P-selectin ntawm vascular endothelial hlwb thiab platelets, thaiv kev cuam tshuam ntawm P-selectin thiab leukocyte PSGL-1, inhibits platelet adhesion ntawm qhov kawg thiab adhesion. txo inflammatory cell infiltration thiab microthrombosis, li no alleviating cov ntaub so ntswg puas thiab ntau o tshwm sim los ntawm ischemia-reperfusion. Nws txo qis infarct loj, cov ntaub so ntswg edema thiab inflammatory kev raug mob nyob rau hauv cov qauv ntawm cerebral ischemia, myocardial ischemia thiab mob ntsws mob. Nws tsom adhesion molecules yam tsis muaj kev cuam tshuam rau coagulation, nrog qis los ntshav txaus tshaj li cov tshuaj antithrombotic. Ischemia-reperfusion raug mob, Kev tshawb fawb Thromboinflammation, Kev raug mob ntawm lub cev, Kev tiv thaiv -adhesion tiv thaiv- mob, Kab mob plawv thiab paj hlwb, Peptide tshuaj txhim kho P- xaiv; Leukocyte-endothelial cell adhesion txoj hauv kev; Ischemic raug mob inflammatory cascade blockade txoj kev

Cim npe nrov: CAS 2130912-34-2 selcopintide, Tuam Tshoj cas 2130912-34-2 selcopintide manufacturers, lwm tus neeg, Hoobkas

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