Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 661472-41-9 relamorelin hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 661472-41-9 relamorelin los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 661472-41-9: Relamorelin |
| Kev piav qhia | Relamorelin yog ib tug tshiab-tiam xaiv loj hlob hormone secretagogue receptor 1a (GHSR-1a) agonist. Amino acid qhov chaw hloov kho ho txhim kho enzymatic degradation kuj. Nws tshwj xeeb khi rau GHSR-1a receptors, txhawb kev loj hlob hormone secretion, thaum txhim kho plab zom mov thiab ua kom lub plab zom mov, thiab tswj kev qab los noj mov thiab lub zog metabolism. Siv rau hauv kev tshawb fawb mechanism ntawm ntshav qab zib gastroparesis, kev ua haujlwm dyspepsia, kev loj hlob hormone tsis txaus thiab lwm yam kab mob, nrog rau kev txhim kho plab hnyuv motility peptide tshuaj. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Theoretical molecular hnyav (Da) | ~ 3300 (peptide dawb, raug rau cov khoom siv hluavtaws tiag) |
| Hom qauv | Site-modified Ghrelin analog, dawb peptide daim ntawv |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv | Ntev (aa) |
| Relamorelin | Relamorelin; RM-131; Ghrelin receptor agonist | Prokinetic, Kev loj hlob hormone nce qib, GHSR-1a agonism, Kev tshawb fawb Gastroparesis, Kev noj qab haus huv kev cai, plab hnyuv peptide | Ghrelin homology caj qaum nrog qhov chaw hloov kho kom txhim kho enzyme tsis kam thiab receptor affinity | Loj hloov peptide, raug rau cov batch MS | - | ~ 3300 (theoretical, pub dawb peptide) | Dawb peptide | ~28 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia Cov Cai | Luv -Lub Sijhawm Cia Cov Cai | Kua Stability | Khoom hmoov ruaj khov |
| PEB-REL003 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted; zam rov qab khov-thaw cycles | ruaj khov rau 1 lub hlis ntawm 2-8℃kaw & qhuav; npaj cov tshuaj aqueous tshiab ua ntej siv | ruaj khov rau 72h ntawm 4 degree; ruaj khov rau 1 lub hlis ntawm -20℃hauv aliquots. ** Dej solubility nruab nrab, soluble hauv dilute acetic acid lossis acidic tsis **. DPP-IV kuj tseem txhim kho, tab sis tseem ua rau endopeptidase degradation | ruaj khov rau 2 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-REL003 | Kev xaiv GHSR-1a agonist uas txhawb kev ua pa ntawm plab, ua kom lub plab zom mov thiab ua rau muaj kev loj hlob hormone secretion | Relamorelin khi rau G protein-coupled GHSR-1a receptor nrog siab tshwj xeeb thiab affinity, activates downstream Gq/11-mediated PLC-IP3-Ca²⁺ taw qhia txoj hauv kev, thiab exerts ntau yam kab mob lom: lub hauv paus, nws ua rau kev loj hlob ntawm pitu; peripherally, nws ua rau lub plab hnyuv du nqaij thiab lub paj hlwb enteric, txhim kho antral contraction, tswj gastroduodenal motility, accelerates plab hnyuv plab, thiab txhim kho cov tsos mob gastroparesis. Nws kuj ua rau lub chaw noj zaub mov hypothalamic tswj kev qab los noj mov thiab lub zog metabolism. Piv nrog rau cov haiv neeg Ghrelin, nws qhov chaw hloov kho tsis txhob ceev enzymatic cleavage los ntawm DPP-IV, txuas ntxiv nyob rau hauv vivo ib nrab-lub neej los ntawm ob peb folds nrog ntev ntev. | Mob ntshav qab zib gastroparesis, Functional dyspepsia, Kev loj hlob hormone secretion kev tshawb fawb, plab hnyuv motility tsis meej, qab los noj mov & lub zog metabolism, plab hnyuv peptide tshuaj | Kev Loj Hlob Hormone Secretagogue Receptor 1a (GHSR-1a); PLC-IP3-Ca²⁺ taw qhia txoj hauv kev; Gastric motility regulation thiab loj hlob hormone secretion txoj kev |
Cim npe nrov: CAS 661472-41-9 relamorelin, Tuam Tshoj cas 661472-41-9 relamorelin manufacturers, lwm tus, Hoobkas
