Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov chaw muag khoom ntawm cas 2192215-74-8 hynic-ipsma hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 2192215-74-8 hynic-ipsma los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 2192215-}74-8:HYNIC-iPSMA |
| Kev piav qhia | HYNIC-iPSMA yog ib qho tshwj xeeb prostate-specific membrane antigen (PSMA) tsom rau chelating peptide. Nws cov tub ntxhais yog qhov ua tau zoo PSMA me me -molecule inhibitor pharmacophore, nrog rau HYNIC bidentate chelator conjugated rau sab saw. Nws ua haujlwm tau zoo radiolabeling nrog nuclides xws li 99mTc, thiab yog siv rau hauv SPECT imaging, qog staging thiab kho cov kev ntsuam xyuas ntawm prostate cancer. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Theoretical molecular formula | C₃₄H₄₉N₉O₁₁ |
| Theoretical molecular hnyav (Da) | 759.81 (raws li qhov tseeb hluavtaws batch) |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Puv Amino Acid Sequence | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | N-Terminal Hloov kho | C-Terminal Hloov kho | Qhov ntev (aa) |
| HYNIC-iPSMA | Txhim kho HYNIC-PSMA; Prostate cancer imaging precursor; CAS Nr .: 2192215-74-8 | PSMA targeting, 99mTc SPECT imaging, Prostate cancer research, HYNIC chelator, qog neovasculature targeting, Nuclear tshuaj ntsuam xyuas ua ntej | Glutamic acid-urea-lysine (urea-linked core pharmacophore, lysine side chain conjugated nrog HYNIC chelator) | Theoretical C₃₄H₄₉N₉O₁₁, raug rau cov khoom siv tiag tiag | 759.36 (theoretical) | 759.81 (theoretical) | Tsis muaj amine dawb, ob qhov kawg kaw los ntawm urea daim ntawv cog lus | Ob pawg carboxyl dawb, sab - chain chelator hloov kho | 2 (tub ntxhais amino acid qaum qaum nrog urea daim ntawv cog lus thiab kev hloov kho tsis raug cai) |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia Cov Cai | Luv -Lub Sijhawm Cia Cov Cai | Kua Stability | Khoom hmoov ruaj khov |
| PEB-HPSMA001 | hmoov dawb | Khaws ntawm -20 degree, nruj me ntsis tiv thaiv los ntawm lub teeb, kaw thiab qhuav, khaws cia hauv nitrogen hauv aliquots; zam rov qab khov-thaw cycles. ** nruj me ntsis txwv tsis pub hnyav hlau ions ** | Khoom hmoov ruaj khov rau 2 xyoos ntawm 2-8℃kaw thiab qhuav; npaj cov tshuaj aqueous tshiab ua ntej siv | ruaj khov rau 72 h ntawm 4 degree; ruaj khov rau 1 lub hlis ntawm -20℃hauv aliquots. ** Cov dej zoo solubility, dawb do soluble hauv dej thiab physiological tsis **. Hydrazino pab pawg ua rau oxidative degradation, npaj nrog deoxygenated dej, cais tawm ntawm huab cua thiab muaj zog oxidizing neeg sawv cev. Cov hlau hnyav ions nyob hauv qhov chaw chelation thiab txo cov kev ua haujlwm ntawm radiolabeling | Ruaj khov rau 3 xyoos ntawm -20℃nyob rau hauv qhuav, tsaus thiab nitrogen cua |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-HPSMA001 | PSMA- tsom rau HYNIC chelating peptide, daim ntawv lo nrog 99mTc rau kev mob qog noj ntshav prostate SPECT cov duab nrog cov qog nqaij hlav tshwj xeeb | HYNIC-iPSMA yog qhov ua kom zoo rau prostate- tshwj xeeb membrane antigen (PSMA) tsom rau chelating peptide. Nws cov pob txha tseem ceeb yog Glu- urea-Lys PSMA me-molecule inhibitor pharmacophore, khi nrog cov ntsiab lus siab rau PSMA cov protein ntau uas tau nthuav tawm ntawm cov qog nqaij hlav qog noj ntshav thiab qog neovasculature. Sab-chain covalently conjugated HYNIC (6-hydrazinonicotinamide) yog bidentate chelator uas ua kom ceev thiab ruaj khov chelation ntawm radionuclides xws li 99mTc nyob rau hauv stannous ion mediation, nrog rau cov ntawv me me thiab cov ntawv sau siab yield. Piv nrog rau thawj - tiam PSMA chelating peptides, cov qauv kev ua kom zoo tau ua tiav cov qog noj ntshav ntau dua thiab qis dua tsis yog - lub raum tshwj xeeb thiab kab mob siab tom qab, nrog cov teeb liab zoo dua qub - rau- suab nrov piv. Nws ua haujlwm raws li cov cuab yeej tseem ceeb rau kev kuaj mob qog noj ntshav prostate ntxov, qog nqaij hlav, kuaj pom lymph node metastasis, tshuaj ntsuam xyuas kev ua tau zoo thiab PSMA lub hom phiaj kev tshawb fawb. | Kev tshawb nrhiav mob qog noj ntshav prostate, Nuclear tshuaj SPECT imaging txoj kev tshawb fawb, qog tsom rau kev kuaj mob, PSMA txoj kev tshawb fawb, Radiopharmaceutical txoj kev loj hlob, qog neovasculature tshawb fawb | Prostate-Specific Membrane Antigen (PSMA); HYNIC hlau chelation site; Cov qog nqaij hlav receptor- phiaj xwm phiaj xwm txoj kev |
Cim npe nrov: cas 2192215-74-8 hynic-ipsma, Tuam Tshoj cas 2192215-74-8 hynic-ipsma manufacturers, lwm tus neeg, Hoobkas
