Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas: 34273-11-1 (dawb peptide) saralasin tfa hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas: 34273-11-1 (dawb peptide) saralasin tfa los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 34273-11-1 (dawb peptide) Saralasin TFA |
| Kev piav qhia | Saralasin yog thawj cov khoom sib tw sib tw angiotensin Ⅱ antagonist, ib qho octapeptide structural analog. Nws sib tw khi rau AT1 receptors ntawm vascular du leeg, thaiv cov vasoconstrictive thiab pressor los ntawm endogenous angiotensin Ⅱ, exerts hypotensive teebmeem, thiab muaj zog ib feem agonist kev ua. Nws yog ib qho cuab yeej classic peptide rau renin-angiotensin system kev tshawb fawb, kev tshawb fawb txog kev kub siab thiab kev kuaj ntshav renovascular hypertension, dav siv hauv cov kws kho mob plawv, receptor functional identification thiab antihypertensive drug development tests. |
| Peptide Purity (HPLC, %) | 95% / 98% / 99% |
| Dawb peptide molecular mis | C₄₂H₆₅N₁₃O₁₀ |
| Dawb peptide molecular hnyav (Da) | 912.05, siab dua rau TFA ntsev daim ntawv |
| Hom qauv | Hloov kho octapeptide, N-terminal sarcosine hloov kho, trifluoroacetate ntsev |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Saralasin TFA | Saralasin trifluoroacetate hmoov | Kev sib tw AT1 receptor antagonist, hypotensive, renin -angiotensin system tshawb fawb | Angiotensin Ⅱ octapeptide analog nrog Asp1 → sarcosine (Sar) thiab Phe8 → Ala; khaws cov receptor binding kev ua si nrog tsawg heev intrinsic kev ua si, kev sib tw antagonist nrog tsis muaj zog ib feem agonist kev ua | Dawb puag: C₄₂H₆₅N₁₃O₁₀; Daim ntawv ntsev: C₄₂H₆₅N₁₃O₁₀·xC₂HF₃O₂ | 911.5 | 912.05 | Trifluoroacetate (TFA) | 8 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-SAR001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot kom tsis txhob rov qab khov-thaw mus. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; nkoj ntawm cov pob khov nab kuab pom zoo. | Nyob ruaj khov rau 14 hnub ntawm 4 degree. Dawb soluble hauv dej, dilute acetic acid thiab physiological buffers. Aqueous tov yog raug rau proteolytic degradation; aliquot sterilely thiab khov tom qab reconstitution. | ruaj khov rau 3 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-SAR001 | Thawj hluavtaws sib tw AT1 antagonist, cuab yeej rau renin -angiotensin system tshawb fawb | Saralasin yog thawj cov khoom sib tw sib tw angiotensin Ⅱ antagonist, ib qho octapeptide structural analog. Nws sib tw khi rau AT1 receptors ntawm vascular du leeg, thaiv cov vasoconstrictive thiab pressor los ntawm endogenous angiotensin Ⅱ, exerts hypotensive teebmeem, thiab muaj zog ib feem agonist kev ua. Nws yog ib qho cuab yeej classic peptide rau renin-angiotensin system kev tshawb fawb, kev tshawb fawb txog kev kub siab thiab kev kuaj mob sib txawv ntawm renovascular hypertension, dav siv hauv cov tshuaj plawv plawv, kev txheeb xyuas cov neeg ua haujlwm thiab cov tshuaj tiv thaiv kab mob siab. | Kev tshawb fawb txog kev mob ntshav siab, renin- kev tshawb fawb angiotensin system, tshuaj kho mob plawv, receptor functional identification, antihypertensive drug development | Angiotensin Ⅱ hom 1 receptor (AT1R); Vasoconstriction / ntshav siab tswj txoj hauv kev |
Cim npe nrov: CAS: 34273-11-1 (dawb peptide) saralasin tfa, Tuam Tshoj cas: 34273-11-1 (dawb peptide) saralasin tfa manufacturers, lwm tus neeg, Hoobkas
