Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm CAS 2863659-22-5 Relamorelin TFA hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo CAS 2863659-22-5 Relamorelin TFA los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 2863659-22-5: Relamorelin TFA |
| Kev piav qhia | Relamorelin yog ib tug tshiab - tiam ntev - ua ghrelin receptor (growth hormone secretagogue receptor, GHSR) agonist. Nws tshwj xeeb khi rau GHSR receptors nyob rau hauv lub caj pas pituitary thiab plab hnyuv, muaj zog txhawb kev loj hlob hormone tso tawm, thiab siv ntau yam kev lom neeg ntawm kev txhawb nqa plab hnyuv, ua kom qab los noj mov thiab tswj cov metabolism hauv lub zog. Nrog rau kev ua kom zoo dua qub thiab kev hloov pauv fatty acylation, nws qhov kev tiv thaiv rau peptidase degradation yog qhov zoo dua qub, thiab nws hauv vivo ib nrab - lub neej ntev dua li haiv neeg ghrelin, txhawb kev ncua sijhawm ntev. Nws qhia meej cov kev ua haujlwm tshuaj hauv cov kab mob xws li kev mob plab hnyuv, kev loj hlob hormone tsis txaus thiab kev ua haujlwm dyspepsia, thiab yog cov cuab yeej tseem ceeb peptide rau ghrelin system muaj nuj nqi tshawb fawb thiab metabolic / gastrointestinal kab mob peptide tshuaj txhim kho. |
| Peptide Purity (HPLC, %) | 95% / 98% / 99% |
| Dawb puag molecular mis | C₁₄₉H₂₄₈N₄₂O₄₂ |
| Dawb puag molecular hnyav (Da) | 3352.85, siab dua rau TFA ntsev daim ntawv |
| Hom qauv | Hloov pauv peptide, fatty acylation hloov kho, trifluoroacetate ntsev |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Relamorelin TFA | RM-131 TSI | GHSR / ghrelin receptor agonist, txhawb nqa GH tso tawm, txhawb lub plab zom mov, ua kom qab los noj mov | Ntev - ua yeeb yam ghrelin structural analog retaining fatty acylation active hloov kho; kev ua kom zoo ib yam zoo heev txhim kho peptidase tsis kam thiab hauv vivo ib nrab -lub neej; TFA ntsev txhim kho formulation stability | Dawb puag: C₁₄₉H₂₄₈N₄₂O₄₂ | 3350.84 | 3352.85 | Trifluoroacetate (TFA) | 28 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-REL001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb, hauv qab cua nitrogen. Aliquot kom tsis txhob rov qab khov-thaw mus. | ruaj khov rau 2 xyoos ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau luv - lub sij hawm shipping ntawm ambient kub. | ruaj khov rau 7 hnub ntawm 4 degree. Solubility: ~ 80 mg / mL hauv DMSO (yuav tsum tau sonication); me ntsis soluble hauv dej ntshiab. Npaj aqueous tov los ntawm serial dilution los ntawm DMSO Tshuag. Fatty acyl side chain tends ua rau peptide aggregation. | ruaj khov rau 3 xyoos ntawm -20℃thiab 2 xyoos ntawm 4 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-REL001 | Ntev - ua yeeb yam ghrelin receptor agonist txhawb nqa GH tso tawm thiab ua rau lub plab zom mov | Relamorelin yog ib tug tshiab - tiam ntev - ua kev loj hlob hormone secretagogue receptor (GHSR / ghrelin receptor) agonist. Nws tshwj xeeb khi rau GHSR receptors nyob rau hauv lub caj pas pituitary thiab plab hnyuv, muaj zog txhawb kev loj hlob hormone tso tawm, thiab siv ntau yam kev lom neeg ntawm kev txhawb nqa plab hnyuv, ua kom qab los noj mov thiab tswj cov metabolism hauv lub zog. Nrog rau kev ua kom zoo dua qub thiab kev hloov pauv fatty acylation, nws qhov kev tiv thaiv rau peptidase degradation yog qhov zoo dua qub, thiab nws hauv vivo ib nrab - lub neej ntev dua li haiv neeg ghrelin, txhawb kev ncua sijhawm ntev. Nws qhia meej txog kev ua tshuaj pharmacological hauv cov qauv kab mob xws li kev mob plab hnyuv, kev loj hlob hormone tsis txaus, kev ua haujlwm dyspepsia thiab gastroparesis. Nws yog cov cuab yeej tseem ceeb peptide rau ghrelin system ua haujlwm tshawb fawb thiab metabolic / gastrointestinal kab mob peptide tshuaj txhim kho. | Kev loj hlob hormone deficiency kev tshawb fawb, gastroparesis / gastrointestinal motility tsis meej txoj kev tshawb fawb, functional dyspepsia, ghrelin system functionality, metabolic kab mob tshuaj txhim kho | Kev loj hlob hormone secretagogue receptor (GHSR / ghrelin receptor); GH secretion thiab gastrointestinal motility tswj txoj kev |
Cim npe nrov: CAS 2863659-22-5 Relamorelin TFA, Tuam Tshoj CAS 2863659-22-5 Relamorelin TFA manufacturers, lwm tus, Hoobkas
