Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas: 60189-34-6: tetracosactide acetate hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas: 60189-34-6: tetracosactide acetate los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 60189-34-6: Tetracosactide acetate |
| Kev piav qhia | Tetracosactide yog N-terminal 24-mer active fragment ntawm haiv neeg adrenocorticotropic hormone (ACTH), muaj tag nrho cov tseem ceeb domains rau receptor binding thiab lom lom. Nws tshwj xeeb khi rau MC2 receptors ntawm adrenocortical cell membrane, qhib lub cAMP teeb liab txoj hauv kev, thiab koob tshuaj tiv thaiv adrenal cortex kom zais glucocorticoids, mineralocorticoids thiab androgens, nrog rau kev ua haujlwm ntawm lub cev raws li ACTH tag nrho. Clinically siv rau adrenal cortical function stimulation test, thiab kuj rau kev hloov kho ntawm autoimmune thiab inflammatory kab mob. Daim ntawv acetate muaj dej solubility zoo rau kev tsim thiab kev tswj xyuas yooj yim. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Dawb peptide molecular mis | C₁₃₆H₂₁₀N₄₀O₃₁S |
| Dawb peptide molecular hnyav (Da) | 2933.4, siab dua rau daim ntawv acetate |
| Hom qauv | Linear 24-mer, acetate ntsev |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Tetracosactide acetate hmoov | Tetracosactide acetate; TSI (1-24) | Adrenal cortex stimulation, Glucocorticoid secretion, Adrenal function test, Anti-inflammatory anti- tiv thaiv kab mob, Endocrine peptide, Diagnostic reagent | ACTH N-terminal active fragment nrog haiv neeg amino acid sequence | C₁₃₆H₂₁₀N₄₀O₃₁S (dawb peptide) | 2932.58 | 2933.4 | Acetate | 24 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-TET001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted; zam rov qab khov-thaw cycles | ruaj khov rau 2 lub lis piam ntawm 2-8℃kaw & qhuav; ice pob shipping pom zoo | ruaj khov rau 48h ntawm 4 degree; sai degraded los ntawm peptidases nyob rau hauv chav tsev kub nrog cov kev ua si ntse poob, ** zoo solubility dej, dawb soluble nyob rau hauv dej thiab physiological tsis **. Native linear peptide, N-terminal prone rau aminopeptidase cleavage thiab inactivation | ruaj khov rau 2 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov Cheeb Tsam Tshawb Fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-TET001 | ACTH active fragment uas tshwj xeeb nkoos adrenal cortical hormone secretion, rau adrenal function testing thiab anti{0}} inflammatory therapy | Tetracosactide tshwj xeeb khi rau melanocortin 2 receptors (MC2R) ntawm cov cell membrane ntawm adrenal cortical zona fasciculata thiab zona reticularis, activates G protein-mediated adenylate cyclase / cAMP / PKA signaling pathway, sai txhawb kev hloov pauv ntawm cov roj (cholesterol) mus rau pregnenolone, thiab {3} txhawb nqa kev hloov pauv ntawm cov cholesterol mus rau pregnenolone, Kev tso tawm ntawm glucocorticoids (cortisol), mineralocorticoids (aldosterone) thiab androgens. Nws khaws tag nrho cov haujlwm physiological ntawm haiv neeg ACTH, nrog me me molecular hnyav thiab qis immunogenicity. Clinically, nws yog tsuas yog siv rau adrenal cortical muaj nuj nqi stimulation kev ntsuam xyuas los ntsuam xyuas adrenal cia muaj nuj nqi; nws kuj tseem siv tau luv luv -lub sij hawm rau kev hloov kho ntawm autoimmune thiab inflammatory kab mob. | Kev soj ntsuam kev ua haujlwm ntawm adrenal, kev tshawb fawb endocrine physiology, kho kab mob autoimmune, kab mob o, Hypothalamic{0}}pituitary-adrenal axis, Peptide diagnostic reagents | Melanocortin 2 Receptor (MC2R); cAMP/PKA teeb liab txoj kev; Adrenal cortical hormone synthesis thiab secretion txoj kev |
Cim npe nrov: CAS: 60189-34-6: tetracosactide acetate, Tuam Tshoj cas: 60189-34-6: tetracosactide acetate manufacturers, lwm tus neeg, Hoobkas
