Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov chaw muag khoom ntawm arg-arg-arg-arg acetate (tetraarginine acetate) hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo arg-arg-arg-arg acetate (tetraarginine acetate) los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Kev piav qhia | Arg-Arg-Arg-Arg acetate (tetraarginine acetate, RRRR) yog linear cationic oligopeptide muaj li ntawm plaub L-arginine residues, muab raws li acetate ntsev. Cov pab pawg guanidinium ntawm arginine sab chains nqa cov nqi zoo ntawm lub cev pH, sib tham txog tus cwj pwm muaj zog cationic thiab dej solubility. Arginine-nplua nuj luv peptides yog ib qho tseem ceeb ntawm cov cell- nkag mus rau peptides (CPPs) uas tuaj yeem nqa cov khoom thauj khoom (nucleic acids, proteins, nanoparticles) mus rau hauv cov hlwb los ntawm kev nkag mus rau hauv daim nyias nyias los yog endocytosis. Tetraarginine tuaj yeem tsim cov nanocomplexes nrog cov nqi tsis zoo DNA / RNA los ntawm kev sib cuam tshuam ntawm electrostatic, tiv thaiv nucleic acids los ntawm nuclease degradation thiab txhawb nqa cellular uptake, ua rau nws siv dav hauv kev xa cov tsheb thiab kev tshawb fawb txog noob caj noob ces. Tsis tas li ntawd, arginine yog ib qho substrate rau nitric oxide synthase (NOS), thiab tetraarginine kuj tseem siv tau rau hauv TSIS TAU-txog xovtooj ntawm tes thiab vascular biology kev tshawb fawb. Daim ntawv acetate txhim kho peptide dej solubility thiab stability, yooj yim cia thiab formulation. |
| Peptide purity (HPLC) | Ntau dua lossis sib npaug li 95% |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Arg-Arg-Arg-Arg acetate | Tetraarginine acetate; R4 cell-peptide nkag mus | Cell- nkag mus peptide, nucleic acid/tshuaj intracellular xa, gene transfection, cationic carrier | Linear tetra-L-arginine, acetate ntsev; Cov qauv cationic muaj zog nkag mus rau cov cell membranes ntawm electrostatic kev sib cuam tshuam, xa biomacromolecules intracellularly | C₂₀H₄₄N₁₂O₃·C₂H₄O₂ | 516.38 (dawb peptide) | ~ 516.7 (peptide dawb) | Acetate | 4 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-RRR004 | Dawb hmoov | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau shipping ntawm ambient kub. | ruaj khov rau 7 hnub ntawm 4 degree. Muaj zog cationic peptide yog soluble hauv dej, dilute acetic acid thiab acidic buffers. Zoo stability nyob rau hauv acidic rau nruab nrab tej yam kev mob; nqi neutralization thiab nkag mus efficiency txo nyob rau hauv muaj zog alkaline tej yam kev mob. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-RRR004 | Tetraarginine R4, muaj zog cationic CPP, mediates nucleic acid & xa tshuaj | Arg-Arg-Arg-Arg acetate yog ib qho classic luv luv cationic cell- nkag mus rau peptide. Lub zog zoo tshaj tawm cov qauv tsim los ntawm plaub arginines sai khi rau thiab nkag mus rau phospholipid bilayer ntawm cell membranes ntawm electrostatic kev sib cuam tshuam, zoo xa plasmid DNA, siRNA, antisense nucleic acids thiab tshuaj molecule me me rau hauv cytoplasm. Nrog qis cytotoxicity thiab dej solubility zoo, nws yog dav siv nyob rau hauv kev hloov cov noob, kho noob thiab kev tshawb fawb tshuaj intracellular. | Gene transfection & gene therapy, cell -peptide thev naus laus zis, kev xa tshuaj nucleic acid, kev tshawb fawb ntawm tes, kev xa tshuaj | Phospholipid bilayer; electrostatic adsorption transmembrane; endosomal txoj kev khiav tawm |
Cim npe nrov: arg-arg-arg-arg acetate (tetraarginine acetate), Tuam Tshoj arg-arg-arg-arg acetate (tetraarginine acetate) manufacturers, lwm tus neeg, Hoobkas
