Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 850859-24-4 lyp-2 hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau kev lag luam wholesale bulk zoo cas 850859-24-4 lyp-2 los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Kev piav qhia | LyP-2 (CAS: 850859-24-4) yog 9-amino acid disulfide-cyclized peptide nrog cov kab ke Cys-Asn-Arg-Arg-Thr-Lys-Ala-Gly-Cys (CNRRTKAGC), qhov twg ib daim ntawv cog lus disulfide yog tsim los ntawm Cys1 thiab Cys9, tswj cov pideformation nyob rau hauv. LyP-2 yog cov qog lymphatic hlab ntsha- tsom peptide xaiv los ntawm hauv vivo phage zaub thev naus laus zis, uas tuaj yeem tshwj xeeb hauv tsev rau lymphatic hlab ntsha ntawm ntau hom qog. Lub hom phiaj ntawm LyP-2 qhia cov qog nqaij hlav hom heterogeneity: cov kev tshawb fawb tau pom tias LyP-2 tuaj yeem tsom cov hlab ntsha lymphatic hauv C8161 melanoma thiab K14-HPV16 daim tawv nqaij thiab cov qog nqaij hlav hauv tsev menyuam, tab sis tsis yog hauv MDA-MB-435, mob qog nqaij hlav hauv lub mis. cov cim ntawm ntau hom qog. Cov kab ke ntawm LyP-2 muaj ob qhov sib law liag arginines (Arg-Arg) thiab ib qho lysine (Lys), muab cov nqi zoo, uas tuaj yeem ua tiav cov phiaj xwm khi los ntawm kev sib cuam tshuam nrog cov receptors tshwj xeeb lossis cov molecules ntawm cov kab mob lymphatic endothelial. Tsis zoo li LyP-1 peptide cuam tshuam (ib theem CGNKRTRGC, tsom p32 receptor / gC1qR), LyP-2 muaj qhov sib txawv thiab cov phiaj xwm profile, qhia tias nws yuav khi rau cov cim kab mob endothelial sib txawv. Cov ntawv thov ntawm LyP-2 muaj xws li: (1) qog qog lymphatic hlab ntsha - tom qab ntawv cim nrog fluorescent dyes lossis radionuclides, rau kev pom cov qog lymphatic hlab ntsha thiab kev ntsuam xyuas ntawm lymphatic metastasis; (2) qog lymphatic-targeted tshuaj xa - tsom xa cov tshuaj chemotherapeutic, nanoparticles, los yog gene therapy reagents rau qog lymphatic hlab ntsha los inhibit qog lymphatic metastasis; (3) qog lymphatic hlab ntsha kev tshawb fawb txog biology - ua cov cuab yeej peptide los kawm cov yam ntxwv ntawm molecular thiab heterogeneity ntawm qog lymphatic hlab ntsha; (4) qog metastasis mechanism kev tshawb fawb - tshawb xyuas lub luag haujlwm ntawm cov hlab ntsha lymphatic hauv qog metastasis; (5) Kev soj ntsuam qog nqaij hlav - qog lymphatic hlab ntsha ntom ntom thiab lub hom phiaj muaj feem cuam tshuam nrog qog nqaij hlav metastasis. LyP-2 yog cov cuab yeej tseem ceeb peptide rau kev kawm cov qog lymphatic hlab ntsha biology thiab txhim kho lymphatic-targeted theranostic tswv yim. |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| LyP-2 | Lymphoma- phiaj peptide LyP-2; lymphoma-specific khi peptide | Lymphoma targeting, qog- targeted delivery, lymphoma imaging, receptor-binding peptide | Lymphoma- tshwj xeeb heptapeptide tshuaj xyuas los ntawm phage zaub; khi nrog siab affinity rau lub hom phiaj receptors overexpressed ntawm lymphoma hlwb, kho kom haum xeeb tshuaj enrichment | C₃₅H₅₇N₁₁O₉ | 787.43 | ~788.0 | Acetate | 7 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-LYP02 | Dawb hmoov | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau shipping ntawm ambient kub. | ruaj khov rau 7 hnub ntawm 4 degree. Soluble hauv dej, dilute acetic acid thiab PBS. Optimal receptor binding kev ua haujlwm ntawm lub cev pH; Kev hloov pauv thiab kev sib khi ua haujlwm poob raws li muaj zog acid / puag. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-LYP02 | LyP-2 lymphoma-targeting peptide tshwj xeeb khi cov qog ntshav qog ntshav rau cov tshuaj tiv thaiv kab mob | LyP-2 yog ib hom kab mob qog nqaij hlav tshwj xeeb peptide soj ntsuam los ntawm phage zaub. Nws khi nrog siab affinity rau cov yam ntxwv receptors overexpressed ntawm lymphoma hlwb, kho kom haum xeeb enrichment ntawm conjugated chemotherapeutics, fluorescent imaging agents thiab nanoparticles nyob rau hauv cov ntaub so ntswg lymphoma, txhim khu kev ua tau zoo thiab txo cov kev mob tshwm sim. | Lymphoma targeted therapy, qog targeted imaging, targeted drug development, hematologic oncology research, qog molecular diagnosis | Lymphoma cell nto phiaj receptor; receptor-mediated endocytosis; qog- phiaj xwm ntxiv |
Cim npe nrov: CAS 850859-24-4 lyp-2, Tuam Tshoj cas 850859-24-4 lyp-2 manufacturers, lwm tus, Hoobkas
