Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 1239011-83-6 mibenratide hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 1239011-83-6 mibenratide los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 1239011-83-6: Mibenratide |
| Kev piav qhia | Mibenratide yog ib qho hluavtaws-inducing peptide tsim tawm tsam hauv nruab nrab paj hlwb myelin antigens. Los ntawm kev ua raws li cov tub ntxhais epitope ntawm myelin proteins, nws induces antigen tshwj xeeb tiv thaiv kab mob nyob rau hauv lub cev, inhibits kev ua kom thiab proliferation ntawm autoreactive CD4+ T hlwb, txo pro-inflammatory cytokine tso, thiab alleviates inflammatory infiltration thiab myelin puas nyob rau hauv lub hauv paus paj hlwb. Nws cov nyhuv yog antigen tshwj xeeb yam tsis ua rau lub cev tiv thaiv kab mob. Siv rau hauv kev tshawb fawb mechanism ntawm ntau yam sclerosis, autoimmune encephalomyelitis thiab lwm yam kab mob, nrog rau kev tiv thaiv kab mob peptide tshuaj txhim kho. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Theoretical molecular hnyav (Da) | ~ 2600 (raws li qhov tseeb hluavtaws batch MS) |
| Hom qauv | Linear hluavtaws antigen peptide, haiv neeg amino acid sequence |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Hom qauv | Ntev (aa) |
| Mibenratide | Mibenratide; PAB-8298 | Kev tiv thaiv kab mob tiv thaiv kab mob, tiv thaiv - autoimmunity, Kev tshawb fawb ntau yam sclerosis, Antigen- tshwj xeeb, Myelin antigen peptide, Neuroimmunology | Linear myelin epitope peptide nrog optimized T cell paub qhov tseem ceeb sib lawv liag | Loj linear peptide, raws li qhov tseeb batch MS | - | ~ 2600 (theoretical) | Synthetic antigen peptide | ~22 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia Cov Cai | Luv -Lub Sijhawm Cia Cov Cai | Kua Stability | Khoom hmoov ruaj khov |
| PEP-MIB001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted; zam rov qab khov-thaw cycles thiab kis kab mob | ruaj khov rau 2 lub lis piam ntawm 2-8℃kaw & qhuav; ice pob shipping pom zoo | ruaj khov rau 72 h ntawm 4℃nyob rau hauv sterile tej yam kev mob; Nws yooj yim rau protease degradation thiab microbial loj hlob nyob rau hauv chav tsev kub, ** Solubility dej, yuav tsum tau PBS tsis los yog dilute acetic acid rau dissolution **. Linear antigen peptide yooj yim degraded los ntawm cov ntshav proteases | ruaj khov rau 2 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEP-MIB001 | Antigen- tshwj xeeb tiv thaiv kab mob peptide uas inhibits autoreactive T hlwb thiab alleviates central demyelinating o | Mibenratide ua rau cov tub ntxhais T cell epitope ntawm nruab nrab paj hlwb myelin proteins, thiab induces antigen- tshwj xeeb tiv thaiv kab mob los ntawm kev tswj hwm tolerogenic: ntawm ib sab, nws induces kev tswj T cell (Treg) sib txawv rau kev siv tshuaj tiv thaiv kab mob; Ntawm qhov tod tes, nws txhawb kev ntxhov siab thiab apoptosis ntawm autoreactive effector T hlwb, txo lawv cov kev tawm tsam ntawm cov ntaub so ntswg myelin, yog li alleviating inflammatory infiltration, myelin poob thiab neurological puas nyob rau hauv lub hauv paus paj hlwb. Tsis zoo li dav -spectrum immunosuppressants, nws tsuas yog ua rau cov myelin antigens tshwj xeeb yam tsis muaj kev tiv thaiv tag nrho lub cev tiv thaiv kab mob, nrog kev pheej hmoo kis mob tsawg. Nws yog cov cuab yeej tshawb fawb tshiab rau cov kab mob autoimmune demyelinating. | Kev tshawb fawb ntau yam sclerosis, Kev sim tshuaj autoimmune encephalomyelitis, Kev tiv thaiv kab mob tiv thaiv kab mob, Neuroimmunology, Kab mob autoimmune, kev txhim kho tshuaj tiv thaiv Peptide | Myelin antigen- tshwj xeeb T cell receptor; Kev cai T cell induction txoj kev; autoimmune inflammatory inhibitory txoj kev |
Cim npe nrov: CAS 1239011-83-6 mibenratide, Tuam Tshoj cas 1239011-83-6 mibenratide manufacturers, lwm tus, Hoobkas
