Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas: 1444827-29-5: aviptadil acetate hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas: 1444827-29-5: aviptadil acetate los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 1444827-29-5: Aviptadil acetate CAS TSIS TAU |
| Kev piav qhia | Aviptadil yog hluavtaws vasoactive plab hnyuv peptide (VIP), ib qho endogenous pleiotropic vasoactive peptide. Nws exerts ntau yam kab mob lom los ntawm kev nthuav dav VPAC1 thiab VPAC2 receptors: potently relaxes vascular du nqaij, txo pulmonary artery siab thiab txhim kho microcirculation; inhibits pro-inflammatory cytokine tso tawm thiab alleviates inflammatory cascade puas tsuaj; tiv thaiv alveolar epithelial thiab endothelial hlwb thiab txhim kho pulmonary gas exchange. Nws qhia txog kev tiv thaiv cov ntaub so ntswg tseem ceeb thiab kev txhim kho kev ua haujlwm hauv cov qauv ntawm pulmonary hypertension, mob ua pa nyuaj siab thiab ischemia- raug mob reperfusion, thiab yog cov cuab yeej tseem ceeb peptide rau cov kws kho mob plawv, kab mob ua pa thiab kev tshawb fawb txog kev raug mob. |
| Peptide Purity (HPLC, %) | 95% / 98% / 99% |
| Dawb puag molecular mis | C₁₄₇H₂₃₈N₄₂O₄₀ |
| Dawb puag molecular hnyav (Da) | 3325.71, siab dua rau daim ntawv acetate |
| Hom qauv | Linear 28-mer peptide, ib txwm tib neeg kab ke, acetate ntsev |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Aviptadil acetate hmoov | Avptadil acetate; Vasoactive plab hnyuv peptide (VIP) | VPAC receptor agonist, muaj zog vasodilation, tiv thaiv - mob & lub ntsws tiv thaiv, txhim kho microcirculation | Haiv neeg haiv neeg 28-mer vasoactive plab hnyuv peptide, linear haiv ib theem tsis hloov kho, dav activates VPAC1/VPAC2 receptors; acetate daim ntawv ho txhim kho dej solubility thiab formulation stability | Dawb peptide: C₁₄₇H₂₃₈N₄₂O₄₀ | 3324.76 | 3325.71 | Acetate | 28 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-AVI001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot kom tsis txhob rov qab khov-thaw mus. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; nkoj ntawm cov pob khov nab kuab pom zoo. | ruaj khov rau 7 hnub ntawm 4 degree. Dawb soluble hauv dej, PBS thiab lwm yam physiological buffers. Aqueous tov yog sai degraded los ntawm proteases; npaj tshiab ua ntej siv los yog aliquot sterilely thiab khaws cia ntawm -20 degree. | ruaj khov rau 3 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-AVI001 | Endogenous vasoactive plab hnyuv peptide nrog pleiotropic vasodilatory, tiv thaiv - mob thiab cov ntaub so ntswg tiv thaiv | Aviptadil yog hluavtaws vasoactive plab hnyuv peptide (VIP), ib qho endogenous pleiotropic vasoactive peptide dav dav hauv vivo. Nws exerts ntau yam kab mob lom los ntawm kev khi rau dav VPAC1 thiab VPAC2 receptors: potently relaxes vascular du nqaij, txo pulmonary artery siab thiab txhim kho cov nqaij mos microcirculation; inhibits pro-inflammatory cytokine tso tawm thiab alleviates inflammatory cascade thiab cov ntaub so ntswg puas; tiv thaiv alveolar epithelial thiab endothelial hlwb thiab txhim kho pulmonary gas exchange; Nws kuj muaj cov haujlwm neuroprotective thiab immunomodulatory. Nws qhia txog kev tiv thaiv cov ntaub so ntswg tseem ceeb thiab kev txhim kho kev ua haujlwm hauv cov qauv ntawm pulmonary hypertension, mob ua pa nyuaj, ischemia- raug mob rov qab thiab cov kab mob inflammatory. Nws yog cov cuab yeej tseem ceeb peptide rau kev kho mob plawv, kab mob ua pa thiab kev tshawb fawb txog kev raug mob. | Kev tshawb fawb pulmonary hypertension, kev tshawb nrhiav mob ntsws ua pa nyuaj, ischemia- kev tshawb fawb txog kev raug mob reperfusion, kev tshawb fawb inflammatory immunomodulation, kev loj hlob tshuaj tiv thaiv ntsws | Vasoactive plab hnyuv peptide receptor 1/2 (VPAC1 / VPAC2); cAMP teeb liab txoj kev; Vasodilation thiab tiv thaiv - txoj kev inflammatory |
Cim npe nrov: CAS: 1444827-29-5: aviptadil acetate, Tuam Tshoj cas: 1444827-29-5: aviptadil acetate manufacturers, lwm tus neeg, Hoobkas
