Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas 197922-42-2 teduglutide tfa hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau kev lag luam wholesale bulk zoo cas 197922-42-2 teduglutide tfa los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS 197922-42-2 Teduglutide TFA |
| Ib ntus | Nws-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asn-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr- |
| Peb tsab ntawv ib ntus | H-His-Gly-Asp-Gly-Ser-Phe-Ser-Asp-Glu-Met-Asn-Thr-Ile-Leu-Asp-Asn-Leu-Ala-Ala-Arg-Asp-Phe-Ile-Asn-Trp-Leu-Ile-Gln-Thr-Lys-Ile-Thr-Ile |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Cov mis mos molecular | C₁₆₄H₂₅₂N₄₄O₅₅S (dawb puag) |
| Molecular Luj (Da) | 3752.13 |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Amino Acid Tag Nrho Lub Npe Sequence | Molecular Formula | Qhov hnyav Molecular (Da) | Qhov Nruab Nrab Molecular Luj (Da) | N-Terminal Hloov kho | C-Terminal Hloov kho | Qhov ntev (aa) |
| TFA Cov | Teduglutide TFA; Gatex; Revestive; CAS 197922-42-2; Ntev-ua yeeb yam GLP-2 analog | GLP-2 receptor agonist, plab hnyuv epithelial kho, Kev kho mob plab plob tsis so tswj, Kev txhawb nqa khoom noj khoom haus, kev tshawb fawb plab hnyuv, kev txhim kho tshuaj peptide. | Histidine-Glycine-Aspartic acid-Glycine-Serine-Phenylalanine-Serine-Aspartic acid-Glutamic acid-Methionine-Asparagine-Threonine-Isoleucine-Leucine-Aspartic acid-Asparagine-Leucine-Alanine{1{1}{9}1}Alanicine acid-Phenylalanine-Isoleucine-Asparagine-Tryptophan-Leucine-Iso leucine-Glutamine-Threonine-Lysine-Isoleucine-Threonine-Aspartic kua qaub | C₁₆₄H₂₅₂N₄₄O₅₅S (dawb puag) | 3750.78 | 3752.13 | Dawb amine, unmodified | Dawb carboxyl, unmodified | 33 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia Cov Cai | Luv -Lub Sijhawm Cia Cov Cai | Kua Stability | Khoom hmoov ruaj khov |
| PEB-TED001 | hmoov dawb | Khaws ntawm -20 degree, tiv thaiv lub teeb, kaw thiab qhuav, aliquoted; zam rov qab khov-thaw cycles thiab oxidation | Khoom hmoov ruaj khov rau 2 xyoos kaw thiab qhuav ntawm 2-8 degree; npaj aqueous daws freshly ua ntej siv, aliquots ruaj khov rau 1 lub hlis ntawm -20 degree | ruaj khov rau 72 h ntawm 4 degree; methionine residue yog raug rau oxidation, ntev qhib cia tsis pom zoo | ruaj khov rau 3 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Hom phiaj / Receptor |
| PEB-TED001 | Ntev - ua yeeb yam xaiv GLP-2 receptor agonist; txhawb plab hnyuv epithelial proliferation thiab villus loj hlob, nthuav txoj hnyuv absorptive nto cheeb tsam, siv nyob rau hauv plab hnyuv rehabilitation kev tshawb fawb rau luv plob tsis so tswj syndrome. | Teduglutide TFA yog qhov ntev - ua yeeb yam hloov kho analog ntawm tib neeg glucagon-zoo li peptide-2 (GLP-2). Kev hloov pauv ntawm alanine nrog glycine ntawm txoj haujlwm 2 ua rau muaj kev tiv thaiv tseem ceeb rau dipeptidyl peptidase IV (DPP-IV) proteolysis, ua kom ntev ntev hauv vivo ib nrab-lub neej piv rau haiv neeg GLP-2. Nws tau xaiv tau zoo heev ua rau GLP-2 receptors ntawm plab hnyuv epithelial thiab stromal cell membranes, ua rau qis qis cAMP teeb liab txoj hauv kev, txhawb txoj hnyuv crypt qia cell proliferation, nce plab hnyuv siab thiab crypt qhov tob, thiab nthuav dav hauv plab hnyuv nqus qhov chaw. Nws kuj tseem txhim kho txoj hnyuv ua haujlwm, txo cov plab hnyuv plab, thiab txhim kho cov dej thiab kev nqus dej kom zoo. Cov kev tshawb fawb soj ntsuam tau tshawb pom tias nws tuaj yeem txo qis parenteral khoom noj khoom haus dependence nyob rau hauv cov neeg mob uas muaj plab plob tsis so tswj syndrome thiab txhawb txoj hnyuv rehabilitation. Nws yog cov cuab yeej tseem ceeb molecule rau cov tshuaj hauv plab hnyuv, kev tshawb nrhiav kab mob malabsorption thiab kev txhim kho tshuaj peptide tshiab. | Intestinal pharmacology tshawb fawb, Kev tshawb fawb luv luv plob tsis so tswj, Kev tshawb fawb plab hnyuv, Malabsorption disorder research, Peptide tshuaj txhim kho, mob plab hnyuv kab mob | Glucagon-zoo li peptide-2 receptor (GLP-2R); cAMP/PKA teeb liab txoj kev |
Cim npe nrov: CAS 197922-42-2 teduglutide tfa, Tuam Tshoj cas 197922-42-2 teduglutide tfa manufacturers, lwm tus, Hoobkas
