Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov neeg muag khoom ntawm cas: 61012-19-9: lecirelin hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas: 61012-19-9: lecirelin los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | CAS: 61012-19-9: Lecirelin |
| Kev piav qhia | Lecirelin yog ib qho tshiab -generation synthetic gonadotropin- tso cov tshuaj hormone (GnRH) agonist, ib qho kev ua kom zoo dua qub ntawm cov haiv neeg GnRH. Nws tshwj xeeb khi rau GnRH receptors hauv anterior pituitary caj pas, pib txhawb kev tso tawm ntawm luteinizing hormone (LH) thiab follicle-stimulating hormone (FSH). Kev tswj hwm tsis tu ncua ua rau receptor desensitization thiab nqis - kev tswj hwm ntawm gonadotropin secretion, yog li tswj hwm kev ua haujlwm ntawm gonadal thiab qib tshuaj hormones. Nrog rau kev hloov kho qhov chaw amino acid, nws cov tshuaj tiv thaiv peptidase thiab hauv vivo ib nrab- lub neej zoo dua li cov neeg nyob hauv GnRH, nrog rau kev ua haujlwm lom neeg muaj zog. Nws yog dav siv nyob rau hauv kev tshawb fawb txog kev yug me nyuam ntawm endocrine mechanism, pab txoj kev yug me nyuam, kev sib deev hormone-kev tshawb fawb kab mob thiab lwm yam, thiab yog ib qho tseem ceeb cov cuab yeej peptide rau kev ua me nyuam tshuaj thiab kev tshawb fawb endocrine. |
| Peptide Purity (HPLC, %) | 95% / 98% / 99% |
| Dawb puag molecular mis | C₅₉H₈₄N₁₆O₁₃ |
| Dawb puag molecular hnyav (Da) | 1209.4, siab dua rau daim ntawv acetate |
| Hom qauv | Hloov kho nonapeptide nrog D-amino acid hloov pauv, acetate |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Lecirelin | Lecirelin acetate hmoov | GnRH receptor agonist, kev tsim kho endocrine tswj, gonadotropin hloov kho | Nonapeptide GnRH analog, D-leucine thiab lwm qhov chaw hloov kho txhim kho metabolic stability thiab receptor affinity, ntev - ua raws li kev cai ntawm pituitary gonadotropin secretion | Dawb peptide: C₅₉H₈₄N₁₆O₁₃ | 1208.64 | 1209.4 | Acetate | 9 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-LEC001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot kom tsis txhob rov qab khov-thaw mus. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; nkoj ntawm cov pob khov nab kuab pom zoo. | ruaj khov rau 7 hnub ntawm 4 degree. Dawb soluble nyob rau hauv dilute acetic acid thiab acidic buffers; me ntsis dej solubility. Aqueous tov yog raug rau peptidase degradation; npaj tshiab ua ntej siv. | ruaj khov rau 3 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-LEC001 | Ntev - ua haujlwm GnRH agonist nrog bidirectional kev tswj ntawm gonadotropin secretion | Lecirelin yog ib qho tshiab -generation synthetic gonadotropin- tso cov tshuaj hormone (GnRH) agonist, ib qho kev ua kom zoo dua qub ntawm cov haiv neeg GnRH. Nws tshwj xeeb khi rau GnRH receptors hauv anterior pituitary caj pas. Kev tswj hwm thawj zaug txhawb kev tso tawm ntawm luteinizing hormone (LH) thiab follicle-stimulating hormone (FSH); Kev tswj hwm tas li induces receptor internalization thiab desensitization, down - tswj gonadotropin secretion, yog li inhibiting gonadal muaj nuj nqi thiab txo cov qib tshuaj hormones. Nrog rau kev hloov kho qhov chaw amino acid, nws cov tshuaj tiv thaiv peptidase thiab hauv vivo ib nrab- lub neej zoo dua li cov neeg nyob hauv GnRH, nrog rau kev ua haujlwm lom neeg muaj zog. Nws yog dav siv nyob rau hauv kev tshawb fawb txog kev yug me nyuam ntawm endocrine mechanism, pab txoj kev yug me nyuam, kev sib deev hormone-kev tshawb fawb kab mob thiab lwm yam, thiab yog ib qho tseem ceeb cov cuab yeej peptide rau kev ua me nyuam tshuaj thiab kev tshawb fawb endocrine. | Kev tshawb fawb txog kev yug me nyuam endocrine, pab kev tshawb fawb txog kev yug me nyuam, kev sib deev hormone-kev tshawb nrhiav kab mob, GnRH receptor function study, tsiaj txhu kev cai tshawb fawb | Gonadotropin{0}} tso cov tshuaj hormone receptor (GnRHR); Pituitary-gonadal axis hormone secretion tswj txoj hauv kev |
Cim npe nrov: CAS: 61012-19-9: lecirelin, Tuam Tshoj cas: 61012-19-9: lecirelin manufacturers, lwm tus, Hoobkas
