Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm cas 2156606-61-8 ac-ihihiyi-nh2 hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo cas 2156606-61-8 ac-ihihiyi-nh2 los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | Ac-IHIHIYI-NH2 |
| Kev piav qhia | Ac-IHIHIYI-NH₂ (Ac-Ile-His-Ile-His-Ile-Tyr-Ile-NH₂), CAS 2156606}{11} ration is pH{14}} teb tus kheej - sib sau ua ke heptapeptide. Nws N-terminal acetylation thiab C-terminal amidation modifications blocks terminal charges, txhim kho molecular stability. Cov saw peptide tau txais kev hloov pauv amino acid tsim: isoleucine (Ile, muaj zog hydrophobic residue muab hydrophobic tsav quab yuam) thiab histidine (Nws, muaj imidazole nplhaib nrog pKa ≈ 6.0, muaj pH- teb protonation / deprotonation zog) nrog tyrosicine (tseem hu ua rosicine), π-π stacking thiab hydrophobic kev sib cuam tshuam, thaum muab cov fluorescence intrinsic rau characterization) qhia ze rau C-terminus. Qhov kev hloov pauv no tso cai rau cov saw hlau peptide, hauv lub xeev histidine deprotonated (pH > pKa, nruab nrab imidazole nplhaib), rau tus kheej - sib sau ua ke los ntawm kev sib cuam tshuam hydrophobic ntawm isoleucine side chains, π-π stacking thiab hydrogen bonding ntawm histidine - cov ntawv sib dhos ntawm aromatic rings, nanofibers thiab ntxiv hydrogels; Thaum pH txo qis hauv cov histidine pKa, lub nplhaib imidazole dhau los ua protonated thiab muaj txiaj ntsig zoo, ua rau muaj kev cuam tshuam ntawm electrostatic repulsion, cuam tshuam rau tus kheej- cov qauv sib dhos, thiab ua rau gel{29}} hloov pauv. Qhov pH no- teb tus kheej- kev coj tus cwj pwm sib sau ua ke yog qhov hloov pauv tau thiab hloov tau, ua Ac-IHIHIYI-NH₂ yog lub tsev zoo tshaj plaws rau kev tsim cov khoom siv ntse. Nws cov ntawv thov suav nrog: pH-cov tshuaj tswj tau cov tshuaj tso tawm (ua rau cov tshuaj tso tawm hauv cov qog microacidic ib puag ncig lossis endosomal acidic mob), txhaj tshuaj hydrogels, cell kab lis kev cai scaffolds, biosensors (gel-sol transforms los ntawm pH hloov tau hloov mus rau hauv optical los yog hluav taws xob teeb liab), tswj encapulation thiab proteins. stimuli- teb cov ntaub ntawv mos cov ntaub ntawv tshawb fawb. Lub intrinsic fluorescence ntawm tyrosine residues kuj siv tau rau daim ntawv lo-dawb saib xyuas ntawm peptide tus kheej-assembly txheej txheem thiab microenvironmental hloov. |
| Peptide Purity (HPLC, %) | Ntau dua lossis sib npaug li 98% |
| Cov mis mos molecular | C₄₇H₇₂N₁₂O₉ |
| Molecular Luj (Da) | 949.15 |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Ac-IHIHIYI-NH2 | Acetylated heptapeptide IHIHIYI amide; pH- teb tus kheej - sib dhos peptide | Stimuli- teb tus kheej- sib sau peptide, ntse hydrogel, tswj cov tshuaj tso tawm, biomaterials | N-terminally acetylated thiab C-terminally amidated linear heptapeptide (Ile-Nws-Ile-Nws-Ile-Tyr-Ile); alternating hydrophobic isoleucine thiab histidine enables pH - teb tus kheej - sib dhos rau hauv nanofibers thiab ntse hydrogels | C₄₉H₇₃N₁₁O₈ | 939.56 | ~940.2 | Acetate | 7 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-IHI001 | Dawb hmoov | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau shipping ntawm ambient kub. | ruaj khov rau 7 hnub ntawm 4 degree. pH- teb peptide: histidine yog protonated nrog zoo solubility nyob rau hauv acidic tej yam kev mob; deprotonated ntawm nruab nrab rau alkaline pH, ua rau tus kheej - sib dhos rau hauv nanofibers thiab hydrogels. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-IHI001 | Ac-IHIHIYI-NH2 pH- teb tus kheej- sib sau heptapeptide rau ntse hydrogel xa tshuaj | Ac-IHIHIYI-NH2 yog pH- teb tus kheej- sib sau ua ke heptapeptide. N-terminal acetylation thiab C-terminal amidation txhim kho peptide stability. Alternating hydrophobic isoleucine thiab protonatable histidine nyob rau hauv ib theem ua kom muaj kev sib cais nyob rau hauv acidic tej yam kev mob thiab nws tus kheej- sib dhos rau hauv nanofibers thiab hydrogels ntawm hydrophobic kev sib raug zoo thiab hydrogen bonding ntawm nruab nrab rau alkaline pH. Nrog cov lus teb ceev ceev thiab zoo biocompatibility, nws yog siv hauv kev xa tshuaj ntse, cell encapsulation thiab cov ntaub so ntswg engineering. | Ntse biomaterials, stimuli- teb hydrogels, tswj cov tshuaj xa cov tshuab, cov ntaub so ntswg engineering, tus kheej- sib dhos peptide kev tshawb fawb | Histidine protonation / deprotonation; -daim ntawv tus kheej- sib dhos; pH-kev hloov pauv hloov pauv |
Cim npe nrov: cas 2156606-61-8 ac-ihihiyi-nh2, Tuam Tshoj cas 2156606-61-8 ac-ihihiyi-nh2 manufacturers, lwm tus neeg, Hoobkas
