Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm dota-ubiquicidin (29–41) hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo dota-ubiquicidin (29–41) los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | DOTA-ubiquicidin (29–41) |
| Kev piav qhia | DOTA-ubiquicidin (29–41) yog radioligand precursor nyob rau hauv uas lub DOTA (1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid) macrocyclic chelator yog conjugated {6} cov tshuaj tiv thaiv kab mob peptide ubiquicidin (UBI) fragment 29-41. UBI₂₉₋₄₁ (Thr-Gly-Arg-Ala-Lys-Arg-Arg-Met-Gln-Tyr-Asn-Arg{3} aid 1 {30} antimicrobial fragment los ntawm C-terminal cheeb tsam ntawm UBI, uas khi rau cov kab mob thiab fungal cell membranes los ntawm electrostatic thiab hydrophobic kev sib tshuam, nthuav dav-spectrum antimicrobial kev ua. Vim nws muaj kev sib raug zoo siab rau cov kab mob kab mob, ⁶⁸Ga-labeled DOTA-UBI₂₉₋₄₁ tuaj yeem siv rau PET / CT duab ntawm qhov chaw kis kab mob, ua kom muaj kev sib txawv ntawm cov kab mob thiab cov kab mob sterile. DOTA chelator tsim cov complexes ruaj khov nrog ntau yam radionuclides suav nrog ⁶⁸Ga, ⁶⁴Cu, thiab ¹⁷⁷Lu, ua rau nws yog ib qho tseem ceeb hauv kev kuaj kab mob molecular imaging thiab antimicrobial targeted theranostics. |
| Peptide Purity (HPLC, %) | Ntau dua lossis sib npaug li 95% |
| Cov mis mos molecular | C₈₄H₁₄₇N₃₅O₂₅S |
| Molecular Luj (Da) | ~ 2079.39 Nws |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| DOTA-ubiquicidin (29–41) | DOTA-ubiquicidin 29-41; kab mob-tshaj hom phiaj nuclear peptide | Kev kis kab mob- phiaj xwm duab, tshuaj tua kab mob, tshuaj tua kab mob nuclear, macrocyclic chelating peptide | N-terminal DOTA macrocyclic chelator hloov ubiquicidin active fragment (residues 29–41, 13-mer); DOTA muab multidentate chelation rau radionuclides; peptide khaws cov tshuaj tiv thaiv kab mob thiab cov kab mob-targeting kev ua haujlwm | C₇₉H₁₂₈N₂₆O₂₃ | 1777.95 | ~1779.2 | Acetate | 13 (13-mer + DOTA) |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-DUB029 | Dawb hmoov | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau shipping ntawm ambient kub. | ruaj khov rau 7 hnub ntawm 4 degree. Soluble nyob rau hauv dilute acetic acid, PBS thiab ib txwm saline. Macrocyclic chelating pab pawg tau yooj yim khi hnyav hlau ions. Tsis txhob ua ke nrog siab - concentration hlau ntsev. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov Cheeb Tsam Tshawb Fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-DUB029 | DOTA-ubiquicidin(29-41) lub hom phiaj kab mob kab mob rau radionuclide imaging localization | DOTA-ubiquicidin(29-41) yog tus kab mob- phiaj xwm nuclear theranostic peptide. Nws khaws cov kab mob - tsom mus rau cov khoom tawg yooj yim ntawm ubiquicidin antimicrobial peptide, tshwj xeeb khi cov kab mob ntawm cov phab ntsa ntawm tes thiab sib sau ntawm cov kab mob foci. N-terminal DOTA macrocycle stably chelates radionuclides xws li ⁶⁸Ga thiab ¹⁷⁷Lu, ua kom muaj chaw nyob thiab kuaj kab mob ntawm tus kab mob los ntawm PET / SPECT imaging, nrog rau cov kab mob kis tau tus mob. Nws yog ib qho cuab yeej tseem ceeb rau kev tshawb fawb tshuaj nuclear ntawm cov kab mob sib kis. | Kev kuaj kab mob tshuaj tua kab mob, tshuaj tua kab mob tua kab mob, tshuaj tua kab mob nuclear, kev kuaj kab mob kab mob, tshuaj tua kab mob | Kab mob cell phab ntsa peptidoglycan; DOTA hlau chelation site; kis kab mob- phiaj xwm ntxiv |
Cim npe nrov: dota-ubiquicidin (29–41), Tuam Tshoj dota-ubiquicidin (29–41) manufacturers, lwm tus neeg, Hoobkas
