Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov chaw muag khoom ntawm daim nyias nyias -permeable sequence, mps hauv Suav teb, kuj txhawb kev pabcuam kev cai. Zoo siab txais tos rau cov lag luam wholesale bulk zoo membrane-permeable sequence, mps los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Kev piav qhia | Membrane-Permeable Sequence (MPS, CAS: 1231898-22-}8) yog 17-amino acid cell- nkag mus rau peptide nrog cov kab ke AAVALLPAVLLALLAK, muab los ntawm daim nyias nyias{{13}sequ's permeable sarcoma-sociated herpesvirus (KSHV). Qhov sib lawv liag ntawm MPS yog hydrophobic heev, muaj feem ntau ntawm hydrophobic residues xws li alanine (Ala, 6), leucine (Leu, 6), thiab valine (Val, 2), nrog tsuas yog ib qho zoo lysine residue ntawm C-terminus, thiab nws tag nrho cov qauv zoo ib yam li thaj tsam ntawm hydropho. MPS tuaj yeem nkag mus rau cov cell membranes tau zoo los ntawm kev sib cuam tshuam nrog hydrophobic nrog cov cell membrane lipid bilayer, thiab nws cov txheej txheem transmembrane tuaj yeem cuam tshuam ncaj qha rau hauv daim nyias nyias thiab translocation es tsis yog txoj hauv kev endocytic. Lub C-terminal lysine residue ntawm MPS muab cov ntsiab lus zoo thauj tog rau nkoj, yooj yim rau kev khi thawj zaug ntawm peptide rau anionic cell membrane qhov chaw, thiab tseem tuaj yeem siv rau cov khoom sib txuas nrog cov khoom thauj khoom. MPS tuaj yeem siv los xa cov khoom thauj xws li cov proteins, peptides, nucleic acids, thiab cov tshuaj molecule me me rau hauv cov hlwb, thiab yog ib qho tseem ceeb rau kev kawm txog cov txheej txheem nkag mus rau hauv cov membrane ntawm hydrophobic cell-peptides thiab tsim cov tshuaj xa tawm tshiab. Tsis tas li ntawd, qhov siab hydrophobicity ntawm MPS tseem ua rau nws muaj txiaj ntsig zoo rau kev kawm peptide-membrane kev sib cuam tshuam, membrane fusion, thiab lipid bilayer perturbation hauv kev tshawb fawb biophysics. |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Membrane -Permeable Sequence (MPS) | Membrane-permeable sequence peptide MPS; ua tau zoo heev membrane-peptide nkag mus | Cell - nkag mus rau peptide, txhim kho cov membrane permeability, biomacromolecule xa, noob hloov | Arginine- nplua nuj cationic amphiphilic undecapeptide; nkag mus rau cell membranes ntawm dual mechanisms ntawm electrostatic adsorption thiab hydrophobic insertion | C₆₃H₁₀₄N₂₂O₁₁ | 1408.79 | ~1409.8 | Acetate | 11 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-MPS001 | Dawb hmoov | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; ruaj khov rau shipping ntawm ambient kub. | ruaj khov rau 7 hnub ntawm 4 degree. Dawb soluble hauv dej, dilute acetic acid thiab acidic buffers. Zoo stability ntawm cationic amphiphilic peptide nyob rau hauv acidic tej yam kev mob; Nws yooj yim rau kev sib cuam tshuam membrane thiab sib sau ua ke ntawm nruab nrab pH. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-MPS001 | MPS daim nyias nyias-permeable peptide nkag mus rau hauv daim nyias nyias ntawm ob lub tshuab rau kev xa khoom zoo biomacromolecule | Membrane-Permeable Sequence (MPS) yog ib daim nyias nyias ua tau zoo heev -peptide nkag mus nrog cov qauv amphiphilic ntawm alternating cationic arginine thiab hydrophobic amino acids. Nws nkag mus rau cell membranes ntawm ob qho tib si electrostatic adsorption thiab hydrophobic insertion ywj siab ntawm endocytosis. Nws ua tau zoo xa plasmid DNA, siRNA, cov proteins thiab cov tshuaj me me rau hauv cytoplasm. | Gene transfection & gene therapy, intracellular protein delivery, targeted drug research, CPP technology, xa subcellular | Phospholipid bilayer; dual electrostatic + hydrophobic mechanism; endocytosis-independent penetration |
Cim npe nrov: membrane{0}}permeable sequence, mps, Tuam Tshoj membrane-permeable sequence, mps manufacturers, lwm tus neeg, Hoobkas
