Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov chaw muag khoom ntawm antennapedia peptide fam-labeled (fam-labeled penetratin) hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau cov lag luam wholesale bulk zoo antennapedia peptide fam-labeled (fam-labeled penetratin) los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Kev piav qhia | Antennapedia Peptide FAM-labeled yog 5-carboxyfluorescein (5-FAM)-labeled Antennapedia cell-peptide (tseem hu ua Penetratin), nrog rau qhov sib lawv liag 5-FAM-RQIKIWFQNRRMKWKK-NH₂. Cov peptide no tau muab los ntawm thib peb -helix (residues 43-58) ntawm Drosophila Antennapedia homeodomain protein, thiab yog ib qho ntawm cov tshawb pom ntxov tshaj plaws thiab nthuav dav tshaj plaws ntawm tes- nkag mus rau peptides. Cov txheej txheem Penetratin yog nplua nuj nyob rau hauv cov amino acids yooj yim (3 arginines, 3 lysines) thiab hydrophobic aromatic amino acids (2 tryptophans, 1 phenylalanine), txais yuav ib qho amphipathic -helical conformation nyob rau hauv daim nyias nyias ib puag ncig, thiab muaj peev xwm nkag tau mus rau cell membranes los ntawm ob qho tib si directcations thiab transmembrane. cytoplasm thiab nucleus. N-terminal 5-FAM fluorescent daim ntawv lo ua rau lub sijhawm taug qab thiab ntsuas qhov ntau ntawm cov cellular uptake, intracellular localization, thiab kinetics los ntawm fluorescence microscopy, flow cytometry, thiab fluorescence spectroscopy, ua rau nws yog ib qho tseem ceeb rau kev kawm CPP cellular uptake mechanisms, kev xa khoom zoo thiab kev xa khoom. C-terminal amidation txhim kho cov metabolic stability ntawm peptide. FAM-labeled Penetratin yog siv dav hauv kev tshawb fawb ntawm tes-peptide mechanism kev tshawb fawb, kev tshuaj xyuas kev xa tshuaj, kev tshuaj xyuas ntawm tes, thiab raws li kev sojntsuam molecular hauv kev tshawb fawb qog noj ntshav. |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Antennapedia Peptide FAM- tau sau npe | FAM-labeled antennapedia peptide; Antp-FAM cell- nkag mus rau tracer peptide | Fluorescent tracer cell-peptide nkag mus rau hauv cell imaging, subcellular localization kawm, kev ntsuam xyuas kev xa khoom | Antennapedia cell- nkag mus rau peptide ib ntus, terminally covalently sau nrog FAM (carboxyfluorescein); khaws cov kev nkag mus ntawm tes nrog ntsuab fluorescence tracing cov cuab yeej | C₈₈H₁₂₅N₂₇O₂₄ | 1987.93 | ~1989.2 | Acetate | 16 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-ANT002 | Yellow rau daj daj hmoov hmoov | Khaws ntawm -20 degree, kaw, qhuav thiab tiv thaiv los ntawm lub teeb. Aliquot rau cia. | ruaj khov rau 1 lub hlis ntawm 2-8℃nyob rau hauv kaw qhuav; tiv thaiv los ntawm lub teeb thaum xa khoom. | ruaj khov rau 7 hnub ntawm 4 degree. Soluble hauv dej, dilute acetic acid thiab PBS. FAM fluorophore yog rhiab heev rau lub teeb muaj zog thiab UV; Nws muaj feem xyuam rau photobleaching thiab inactivation. Tiv thaiv los ntawm lub teeb thaum tuav thiab khaws cia. | ruaj khov rau 2 xyoos ntawm -20 degree, qhuav thiab tiv thaiv los ntawm lub teeb. |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-ANT002 | FAM-labeled antennapedia peptide rau fluorescent tracing ntawm intracellular xa | FAM-labeled antennapedia peptide yog fluorescent tracer CPP. Nws khaws cov cell nkag tau zoo thiab kev ua haujlwm hauv thaj chaw nuclear ntawm antennapedia peptide, thiab covalently conjugated FAM fluorophore emits ntsuab fluorescence rau tiag tiag -lub sij hawm taug qab ntawm intracellular trafficking, subcellular localization thiab faib. Nws yog siv rau ntau qhov kev ntsuam xyuas ntawm kev nkag mus ntawm tes ua haujlwm thiab kev kawm txog kev xa khoom. | Cell imaging & tracing, CPP mechanism kawm, subcellular localization, xa efficiency assay, fluorescent biolabeling | Phospholipid bilayer; nuclear localization teeb liab txoj kev; FAM Fluorescent Tracing |
Cim npe nrov: antennapedia peptide fam-labeled (fam-labeled penetratin), Tuam Tshoj antennapedia peptide fam-labeled (fam-labeled penetratin) manufacturers, lwm tus neeg, Hoobkas
