Shanghai Sonyt Biotechnology Co., Ltd. yog ib qho ntawm cov ua lag luam thiab cov muag khoom ntawm dusquetide tfa hauv Suav teb, kuj txhawb kev pabcuam kev cai. Txais tos rau kev lag luam wholesale bulk zoo dusquetide tfa los ntawm peb lub hoobkas. Tiv tauj peb kom paub meej ntxiv.
| Khoom npe | Dusquetide TFA |
| Kev piav qhia | Dusquetide yog ib tug tshiab tiam tshiab innate defense regulator peptide (IDR). Nws tsis ncaj qha tua cov kab mob, tab sis tswj kev ua haujlwm ntawm lub cev tiv thaiv kab mob xws li neutrophils thiab macrophages. Ntawm ib sab tes, nws inhibits inflammatory teb thiab cov ntaub so ntswg puas; Ntawm qhov tod tes, nws txhim kho lub cev muaj peev xwm tshem tawm cov kab mob, ua tiav cov nyhuv immunomodulatory dual ntawm "tiv thaiv kab mob - txhim kho kev tiv thaiv". Nws muaj kev kho tseem ceeb thiab kev tiv thaiv ntawm qhov ncauj mucositis thiab plab hnyuv mucosal raug mob los ntawm kev siv tshuaj khomob thiab xov tooj cua, thiab tseem tuaj yeem siv rau kev tshawb fawb txog kev sib kis thiab kab mob thiab kev txhim kho immunomodulatory peptide. Cov ntsev trifluoroacetate yog HPLC purification nruab nrab. |
| Peptide purity (HPLC, %) | 95%/98%/99% |
| Theoretical molecular hnyav (Da) | ~ 1100 (raws li qhov tseeb hluavtaws batch) |
| Hom qauv | Linear nonapeptide, ib txwm amino acid sequence, trifluoroacetate ntsev |
Product Basic Information Table
| Khoom Lub Npe Lus Askiv | Product Abbreviation / Alias | Function Tags (comma-sib cais) | Core Structure | Molecular Formula | Exact Mass (Da) | Qhov nruab nrab MW (Da) | Daim ntawv ntsev | Ntev (aa) |
| Dusquetide TFA | Dusquetide TFA; IDR peptide | Innate immune regulation, kho Mucosal, Anti-mob & tiv thaiv kev txhim kho, Chemoradiotherapy mucositis, Immunomodulatory peptide, Tsis muaj cov kab mob ncaj qha | Innate tiv thaiv regulator nonapeptide qaum nrog optimized immunomodulatory active sequence | Loj linear peptide, raws li qhov tseeb batch MS | - | ~ 1100 (theoretical) | Trifluoroacetate hmoov | 9 |
Physicochemical Solubility & Cia Parameters
| Khoom Code | Qhov tshwm sim | Ntev - Lub Sij Hawm Cia | Luv - Lub Sij Hawm Cia | Kev daws teeb meem | Khoom hmoov ruaj khov |
| PEB-DUS001 | hmoov dawb | Khaws ntawm -20 degree, kaw, qhuav & tiv thaiv los ntawm lub teeb, aliquoted; zam rov qab khov-thaw cycles thiab kis kab mob | ruaj khov rau 2 lub lis piam ntawm 2-8℃kaw & qhuav; ice pob shipping pom zoo | ruaj khov rau 72h ntawm 4℃nyob rau hauv tsis muaj menyuam; Nws yooj yim rau degradation thiab inactivation los ntawm proteases nyob rau hauv chav tsev kub ** zoo solubility dej, dawb soluble nyob rau hauv dej thiab nruab nrab physiological tsis **. Cationic luv peptide yooj yim degraded los ntawm cov ntshav proteases | ruaj khov rau 2 xyoos ntawm -20℃nyob rau hauv qhuav & tsaus ntuj |
Functional Description
| Khoom Code | Frontend Short Summary (rau cov npe tshawb nrhiav) | Cov lus piav qhia txog kev ua haujlwm lom neeg lom neeg | Cov cheeb tsam tshawb fawb (comma- cais) | Lub Hom Phiaj / Txoj Kev |
| PEB-DUS001 | Innate tiv thaiv regulator nonapeptide nrog bidirectional immunomodulation: inhibits kev mob ntau dhau, txhim kho cov tshuaj tiv thaiv kab mob, thiab txhawb kev kho mob mucosal | Dusquetide yog ib qho immunomodulatory peptide muab tau los ntawm tus tswv tsev tiv thaiv peptides. Nws tsis muaj cov tshuaj tua kab mob ncaj qha. Los ntawm kev khi rau cov receptors nyob rau saum npoo ntawm myeloid hlwb thiab tswj cov kev taw qhia intracellular, nws xaiv inhibits kev tso tawm ntau dhau ntawm pro-inflammatory cytokines thiab txo o-cov ntaub so ntswg puas tsuaj, thaum txhim kho phagocytic clearance muaj nuj nqi thiab chemotactic muaj peev xwm ntawm macrophages thiab neurovenses lub cev tiv thaiv kab mob. Nws tuaj yeem ua kom nrawm kho ntawm mucosal epithelium tom qab chemoradiotherapy, txo lub sijhawm kho ntawm mucositis, thiab tsis tsim cov tshuaj tiv thaiv lossis cuam tshuam nrog lub cev tiv thaiv kab mob homeostasis. Nws yog ib tug sawv cev molecule rau tshiab immunomodulatory peptide kev tshawb fawb. | Chemoradiotherapy mucositis, Mucosal raug mob kho, Innate tiv thaiv kab mob, kev tshawb fawb tiv thaiv kab mob, kab mob inflammatory, Immunomodulatory peptide kev loj hlob | Myeloid cell qauv paub receptors; Innate immune signaling tswj txoj kev; Kev kho mob ntawm mucosal thiab immunomodulatory txoj kev |
Cim npe nrov: Tuam Tshoj dusquetide tfa manufacturers, lwm tus neeg, Hoobkas
